O-1602

  ( 6 citations )    
Product Datasheet
Catalog Number:2797
Chemical Name:5-Methyl-4-[(1R,6R)-3-methyl-6-(1-cyclohexen-1-yl]-1,3-benzenediol
Product Details
Citations (6)
Supplemental Products
Reviews
Biological Activity
Analog of cannabidiol that is a potent agonist at the GPR55 cannabinoid receptor (EC50 values are 13, > 30000 and > 30000 nM for GPR55, CB1 and CB2 receptors respectively). Induces activation of RhoA, cdc42 and rac1.
Technical Data
  • M.Wt:
    258.36
  • Formula:
    C17H22O2
  • Solubility:
    Soluble in methyl acetate (supplied pre-dissolved -10mg/ml)
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    317321-41-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for O-1602 include:

6 Citations: Showing 1 - 6
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  1. The novel cannabinoid receptor GPR55 mediates anxiolytic-like effects in the medial orbital cortex of mice with acute stress.
    Authors: Shi
    Mol Brain  2017;10(1):38
  2. Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding
    Authors: Ailte Et al.
    Scientific Reports  2016;6:30336
  3. △(9)-Tetrahydrocannabinol treatment during human monocyte differentiation reduces macrophage susceptibility to HIV-1 infection.
    Authors: Williams Et al.
    Immunol Cell Biol  2014;9:369
  4. A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans.
    Authors: Romero-Zerbo Et al.
    J Endocrinol  2011;211:177
  5. The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment.
    Authors: Schicho Et al.
    Inflamm Bowel Dis  2011;17:1651
  6. Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries.
    Authors: Daly Et al.
    Br J Pharmacol  2010;159:787

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