Human GPR55 (NP_005674) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC0247
R&D Systems VersaClone cDNA Plasmids
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Human GPR55 (NP_005674) VersaClone cDNA Summary

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

Product Datasheets

Background: GPR55

Members of the G protein-coupled receptor (GPCR) family, such as GPR55, play important roles in signal transduction from the external environment to the inside of the cell. GPR55 is a receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca2+ release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. GPR55 is expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. It is expressed in osteoclasts and osteoblasts. GPR55 may play a role in bone physiology by regulating osteoclast number and function. GPR55 may also be involved in hyperalgesia associated with inflammatory and neuropathic pain.

Long Name
G-Protein-Coupled Receptor 55
Entrez Gene IDs
9290 (Human); 227326 (Mouse); 501177 (Rat)
Alternate Names
G protein-coupled receptor 55; Gm218; GPR55; G-protein coupled receptor 55

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