Oct 4 activator; enhances iPSC reprogramming four-fold and accelerates the appearance of iPSC colonies in combination with 4F (Oct4, Sox2, c-Myc and Klf4). Also induces cardiomyocyte-like cells from human fibroblasts, as part of the 9C cocktail (CHIR99021
, AS83541, SC1, Y27632
, SU 16f
, JNJ10198409 and OAC-2)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Identification of Oct4-activating compounds that enhance reprogramming efficiency.
Li et al.
Proc.Natl.Acad.Sci.U S A, 2012;109:20853
Conversion of human fibroblasts into functional cardiomyocytes by small molecules.
Cao et al.