Biological Activity Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Displays higher cytotoxicity and lower nephrotoxicity than analog cisplatin (Cat. No. 2251) and shows antitumor activity in cell lines with acquired cisplatin resistance.
Soluble to 5 mM in water with gentle warming
Store at +4°C
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For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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