Oxaliplatin

Catalog # Availability Size / Price Qty
2623/50
Oxaliplatin | CAS No. 61825-94-3 | Apoptosis Inducer Compounds
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Description: DNA cross-linking antitumor agent
Alternative Names: Eloxatin

Chemical Name: Oxalato[(1R-trans)-1,2-cyclohexanediamine]platinum(II)

Purity: ≥99%

Product Details
Citations (7)
Reviews (1)

Biological Activity

Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Displays higher cytotoxicity and lower nephrotoxicity than analog cisplatin (Cat. No. 2251) and shows antitumor activity in cell lines with acquired cisplatin resistance.

Technical Data

M.Wt:
397.29
Formula:
C8H14N2O4Pt
Solubility:
Soluble to 5 mM in water with gentle warming
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
61825-94-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Oxaliplatin

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Oxaliplatin effectively kills melanoma cell growth in vitro
By Anonymous on 02/14/2019
Species: Human

Oxaliplatin was used at a 20 uM concentration for in vitro culture with SK-MEL-28 and cell viability was monitored over time with live imaging. Arrow indicates when compound was added to media.


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