OXTR Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-02410

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (90%), Monkey (95%), Mouse (95%), Primate (100%), Rat (90%), Sheep (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all OXTR Primary Antibodies »

Product Specifications

Immunogen

A 20 aa synthetic peptide within the N-terminus extracellular domain of human OXTR.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Elephant (95%), Panda (90%), Bat (85%), Canine (85%), Marmoset (80%).

Specificity

Human OXTR. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DOK3 (50%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for OXTR Antibody - BSA Free

Immunohistochemistry-Paraffin: OXTR Antibody - BSA Free [NBP1-02410]

Immunohistochemistry-Paraffin: OXTR Antibody - BSA Free [NBP1-02410]

Immunohistochemistry-Paraffin: OXTR Antibody - BSA Free [NBP1-02410] - Human Ganglion

Applications for OXTR Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry-Paraffin

10-20 ug/ml
Application Notes
IHC-P: validated with heat induced antigen retrieval in pH 6.0 citrate buffer..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: OXTR

The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.

Long Name

Oxytocin Receptor

Alternate Names

OT-R

Entrez Gene IDs

5021 (Human)

Gene Symbol

OXTR

UniProt

P30559

Additional OXTR Products

Product Documents for OXTR Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for OXTR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for OXTR Antibody - BSA Free

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  • Q: I need to know the sequence of the immunogen peptide used to make Oxytocin Receptor Antibody (NBP1-02410). I am trying to find an antibody to stain this receptor in ants, and without knowing which sequence was used to raise the antibody, I cannot know whether it might cross react. Here is the sequence: >Cbir_04764 (amino acid sequence): 388 residues MSYDLSSSSLPLSLSLPSSPSSSSSPSSLEVSDDLRDEYLARWEIAVLTSIFLITIIGNGLVLFALYARRCYQRRKFTRMYFFILHLSIADLLTGLLDVLPQLAWDITFRFQGGAVLCKLIKFGQPFGLYLSSYILTVTAMDRYYAICHPFSYCAVTSRRSKMMVYGAWVLAAILCVPQVFVFSYKEISPGVWECWATFYLKYGERAYITWYSVTQFLLPFIVLVYTYTQICRSIWTSGKMSGVVDFKQGNKASFSLRNRDPFISKALINTIKQTIVVVSLYIITSIPFIGCELWATWDPKASTSPFFTGAAFTILSLLNSLTSCVNPWIYFAFNRELRAALTNFFCRKKDYSLTYDIDAHQNASDVPSTTSSFISRISRLASSKIFG

    A: The amino acird range of the immunogen used to generate this peptide falls within amino acids 1-50 of the human protein according to NP_000907.2. Unfortunately these proteins are so divergent that I can not recommend NBP1-02410 for use in ants.

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