p53 Antibody (197643) [Janelia Fluor® 646]

Name: p53 Antibody (197643) [Janelia Fluor® 646]
Brand: Novus Biologicals
SKU: FAB1746J
Price: 549 USD
Availability: InStock

Novus Biologicals | Catalog # FAB1746J

Submit a review

Product Documents

View Available Conjugates

100% Guarantee

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas
Related Blogs

Key Product Details

Species Reactivity

Mouse

Applications

Immunoprecipitation

Label

Janelia Fluor 646

Antibody Source

Monoclonal Rat IgG_2B Clone # 197643

View all p53 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse p53
Leu28-Phe325
Accession # NP_035770

Specificity

Detects mouse p53 in Western blots.

Clonality

Monoclonal

Host

Rat

Isotype

IgG_2B

Applications for p53 Antibody (197643) [Janelia Fluor® 646]

Application

Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: p53

p53 is a stress-regulated transcription factor that was first identified as an SV40 large T antigen-binding protein. It plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. This antibody can be used for the specific detection of human p53 that is synthesized in the presence of p53 from other species.

Alternate Names

BCC7, LFS1, TP53, TRP53

Gene Symbol

TP53

Additional p53 Products

Product Documents for p53 Antibody (197643) [Janelia Fluor® 646]

Download Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for p53 Antibody (197643) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.