p53: Products

p53 is well known for its key role as a tumor suppressor protein. It is 393 amino acids (aa) in length with a predicted molecular weight of 44 kDa. It belongs to the p53 family that also includes p63 and p73.

"p53" has 76 results in Products.
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Proteome Profiler Human Phospho-Kinase Array Kit 

Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins

Human/Mouse/Rat p53 Antibody 

5 Images
ChIP, ICC/IF, IP, KO, Simple Western, WB

Human Phospho-p53 (S15) Antibody 

4 Images
ICC/IF, IHC, IP, WB

Human/Mouse/Rat p53 Antibody 

2 Images
ICC/IF, IP, WB

Human Phospho-p53 (S46) Antibody 

4 Images
IHC, Simple Western, WB

Proteome Profiler Human Apoptosis Array Kit 

Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies

Human Phospho-p53 (S15) Antibody 

2 Images
CyTOF-reported, Flow, WB

Recombinant Human p53 Protein, CF 

Bioactivity

Recombinant Human His6-p53 Protein, CF 

Enzyme Activity

Pifithrin-α hydrobromide 

p53 inhibitor. Also aryl hydrocarbon receptor agonist

Human Phospho-p53 (S392) Antibody 

2 Images
Simple Western, WB

Human Phospho-p53 (S392) Antibody 

2 Images
ICC/IF, WB

Human Phospho-p53 (S46) Antibody 

Recombinant Monoclonal Antibody.

Human Phospho-p53 (S15) Antibody 

1 Image
CyTOF-ready, Flow, ICC/IF

Pifithrin-μ 

Inhibitor of p53-mitochondrial binding

PRIMA-1MET 

Restores mutant p53 activity

Cyclic Pifithrin-α hydrobromide 

p53 inhibitor

Nutlin-3 

MDM2 antagonist; inhibits MDM2-p53 interaction

Human p53 Antibody 

CyTOF-ready, Flow

PRIMA-1 

Restores mutant p53 activity; induces apoptosis

NSC 146109 hydrochloride 

Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription

RITA 

MDM2-p53 interaction inhibitor

NSC 66811 

MDM2 antagonist. Disrupts MDM2-p53 interaction

CP 31398 dihydrochloride 

p53-stabilizing agent

RETRA hydrochloride 

Antitumor agent; suppresses mutant p53-bearing cancer cells

WR 1065 dihydrochloride 

p53 activator. Also ROS scavenger

MG 101 

Calpain inhibitor; activates p53-dependent apoptosis

MIRA-1 

Restores mutant p53 activity; proapoptotic

Tenovin-1 

Protects against MDM2-mediated p53 degradation

HLI 373 

Hdm2 inhibitor; activates p53-dependent transcription

SJ 172550 

MDMX inhibitor. Disrupts MDMX-p53 interaction

SCH 529074 

Restores mutant p53 activity

PhiKan 083 

p53 stabilizing agent

Piperlongumine 

Induces apoptosis; increases p53 and ROS levels in cancer cells

SP 141 

High affinity MDM2 inhibitor

BMH 21 

RNA polymerase 1 inhibitor; also p53 pathway activator

Idasanutlin 

Potent MDM2 inhibitor; inhibits MDM2-p53 interaction
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