p66 beta Antibody

Novus Biologicals | Catalog # NB100-60645

Novus Biologicals
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human, Mouse

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all p66 beta Primary Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human transcription repressor p66 beta component of the MeCP1 complex (GATA zinc finger domain containing 2B ) using the numbering given in entry NP_065750.1 (GeneID 57

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for p66 beta Antibody

Western Blot: p66 beta Antibody [NB100-60645]

Western Blot: p66 beta Antibody [NB100-60645]

Western Blot: p66 beta Antibody [NB100-60645] - Detection of Mouse p66beta/GATAD2B by Western Blot. Samples: Whole cell lysate (50 ug) from NIH3T3, TCMK-1, and CT26.WT cells. Antibodies: Affinity purified rabbit anti-p66beta/GATAD2B antibody NB100-60645 used for WB at 0.5 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Western Blot: p66 beta Antibody [NB100-60645]

Western Blot: p66 beta Antibody [NB100-60645]

Western Blot: p66 beta Antibody [NB100-60645] - Detection of Human p66beta/GATAD2B on HeLa whole cell lysate using NB100-60645. p66beta/GATAD2B was also immunoprecipitated by rabbit anti-p66beta/GATAD2B antibodies NB100-60646 and NB100-60647.

Applications for p66 beta Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: p66 beta

P66beta/GATAD2B interacts with MBD2 (methyl-CpG-binding domain 2) and MBD3 (methyl-CpG-binding domain 3) and participates in transcriptional repression in association with the MBD2/NuRD and MBD3/NuRD histone deacetylase complexes. P66beta/GATAD2B is SUMOylated in vivo and its repressive activity has been shown to be enhanced by SUMOylation. Alternate names for P66beta/GATAD2B include transcriptional repressor p66 beta, p66/p68, GATA zinc-finger domain-containing protein 2B, FLJ37346, and KIAA1150.

Alternate Names

FLJ37346, GATA zinc finger domain containing 2B, GATA zinc finger domain-containing protein 2B, KIAA1150, MGC138257, MGC138285, p66/p68, P66beta, RP11-216N14.6, transcription repressor p66 beta component of the MeCP1 complex, transcriptional repressor p66-beta

Entrez Gene IDs

57459 (Human)

Gene Symbol

GATAD2B

UniProt

Q8WXI9 (Human)

Additional p66 beta Products

Product Documents for p66 beta Antibody

Certificate of Analysis

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Product Specific Notices for p66 beta Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for p66 beta Antibody

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