Key Product Details

Species Reactivity

Human

Applications

Knockout Validated, Western Blot

Label

Biotin

Antibody Source

Monoclonal Rat IgG2A Clone # 421015
View all Park7/DJ-1 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human Park7
Met1-Asp189
Accession # Q99497

Specificity

Detects endogenous human Park7 in Western blots.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Park7/DJ-1 Antibody (421015) [Biotin]

Application
Recommended Usage

Knockout Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Park7/DJ-1

PARK7, also known as DJ-1, is a member of the peptidase C56 protein family. The PARK-7 protein is a positive regulator of androgen receptor-dependent transcription. It has also been reported to be a potential sensor for oxidative stress, a redox-sensitive chaperone, and a key protein for preventing neuronal oxidative stress and cell death.

PARK7 is highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, and is detected at slightly lower levels in placenta and brain. The protein is also detected in astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa.

Defects in this gene cause the autosomal recessive neurodegenerative disorder early-onset Parkinson's disease 7.

Long Name

Parkinson Disease 7

Alternate Names

DJ-1, DJ1

Gene Symbol

PARK7

Additional Park7/DJ-1 Products

Product Documents for Park7/DJ-1 Antibody (421015) [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Park7/DJ-1 Antibody (421015) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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