PEX5 Antibody

Novus Biologicals | Catalog # NBP2-44324

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all PEX5 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-QHTASDFVAKVDDPK, from the internal region of the protein sequence according to NP_001124495.1; NP_000310.2; NP_001124496.1; NP_001124497.1.

Specificity

This antibody is expected to recognize all reported isoforms (NP_001124495.1; NP_000310.2; NP_001124496.1; NP_001124497.1). Reported variants represent identical protein: NP_001124498.1, NP_001124497.1

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for PEX5 Antibody

Western Blot: PEX5 Antibody [NBP2-44324]

Western Blot: PEX5 Antibody [NBP2-44324]

Western Blot: PEX5 Antibody [NBP2-44324] - Analysis of Human Kidney lysate (35ug protein in RIPA buffer).

Applications for PEX5 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:128000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
Western blot: Approx 70+65kDa bands observed in Human Kidney lysates (calculated MW of 72.3kDa according to NP_001124495.1 and 66.8kDa according to NP_001124496.1). Recommended concentration: 0.1-0.3ug/ml.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PEX5

The product of the PEX5 gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)

Alternate Names

FLJ50634, FLJ50721, Peroxin-5, peroxisomal biogenesis factor 5, Peroxisomal C-terminal targeting signal import receptor, peroxisomal targeting signal 1 receptor, peroxisomal targeting signal import receptor, peroxisomal targeting signal receptor 1, Peroxisome receptor 1peroxin-5, PTS1 receptor, PTS1-BP, PTS1RFLJ51948, PXR1peroxisomal targeting signal 1 (SKL type) receptor

Gene Symbol

PEX5

UniProt

NP_001124495.1 (Human), NP_000310.2 (Human), NP_001124496.1 (Human), NP_001124497.1 (Human)

Additional PEX5 Products

Product Documents for PEX5 Antibody

Certificate of Analysis

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Product Specific Notices for PEX5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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