PHLDA3 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-80683

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (100%), Rat (99%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Western Blot, Flow Cytometry, IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all PHLDA3 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LWKRKRCVLTERGLQLFEAKGTGGRPKELSFARIKAVECVESTGRHIYFTLVTEGGGEIDFRCPLEDPGWNAQITLGLVKFKNQQAIQTVR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PHLDA3 Antibody - BSA Free

PHLDA3 Antibody

Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -

Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -Staining of human colon shows moderate cytoplasmic positivity in glandular cells.
PHLDA3 Antibody

Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -

Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.
PHLDA3 Antibody

Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -

Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -Staining of human urinary bladder shows moderate cytoplasmic positivity in urothelial cells.
PHLDA3 Antibody

Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -

Immunohistochemistry-Paraffin: PHLDA3 Antibody [NBP1-80683] -Staining of human tonsil shows very weak positivity in germinal center cells as expected.

Applications for PHLDA3 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PHLDA3

p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor

Alternate Names

family A, member 2, pleckstrin homology-like domain, family A, member 3, TIH1TDAG51/Ipl homolog 1

Entrez Gene IDs

23612 (Human)

Gene Symbol

PHLDA3

UniProt

Q9Y5J5 (Human)

Additional PHLDA3 Products

Product Documents for PHLDA3 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for PHLDA3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for PHLDA3 Antibody - BSA Free

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Protocols

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FAQs

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