Polycystin 2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-80944

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Polycystin 2 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: REDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQISH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Polycystin 2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Polycystin 2 Antibody [NBP1-80944]

Immunocytochemistry/ Immunofluorescence: Polycystin 2 Antibody [NBP1-80944]

Immunocytochemistry/Immunofluorescence: Polycystin 2 Antibody [NBP1-80944] - Staining of human cell line BJ shows localization to endoplasmic reticulum. Antibody staining is shown in green.
Polycystin 2 Antibody - BSA Free

Polycystin 2 Antibody [NBP1-80944] -

Staining of human hippocampus shows strong cytoplasmic granular positivity in neurons.
Polycystin 2 Antibody - BSA Free

Polycystin 2 Antibody [NBP1-80944] -

Staining of human fallopian tube shows strong cytoplasmic positivity in glandular cells.
Polycystin 2 Antibody - BSA Free

Polycystin 2 Antibody [NBP1-80944] -

Staining of human testis shows strong cytoplasmic positivity in Leydig cells.
Polycystin 2 Antibody - BSA Free

Polycystin 2 Antibody [NBP1-80944] -

Staining of human cerebral cortex shows strong cytoplasmic granular positivity in neurons.
Polycystin 2 Antibody - BSA Free

Polycystin 2 Antibody [NBP1-80944] -

Staining of human skeletal muscle shows no cytoplasmic positivity in myocytes as expected.

Applications for Polycystin 2 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Polycystin 2

Polycystin 2 is encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN.

Alternate Names

APKD2, Autosomal dominant polycystic kidney disease type II protein, MGC138466, MGC138468, PC2, Pc-2, PKD4, polycystic kidney disease 2 (autosomal dominant), Polycystic kidney disease 2 protein, polycystin-2, Polycystwin, R48321, transient receptor potential cation channel, subfamily P, member 2, TRPP2

Entrez Gene IDs

5311 (Human)

Gene Symbol

PKD2

UniProt

Q13563 (Human)

Additional Polycystin 2 Products

Product Documents for Polycystin 2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Polycystin 2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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