Presenilin-1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-33611

Novus Biologicals
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Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Presenilin-1 Primary Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Presenilin-1. The exact sequence is proprietary.

Localization

Endoplasmic reticulum membrane, Multi-pass membrane protein, Golgi apparatus membrane, Multi-pass membrane protein, Cell surface

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Presenilin-1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611]

Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611]

Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611] - Paraffin-embedded mouse brain. Presenilin 1 antibody [C1C2], Internal dilution: 1:500.
Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611]

Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611]

Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611] - Paraffin-embedded Cal27 xenograft, using antibody at 1:100 dilution.
Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611]

Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611]

Immunohistochemistry-Paraffin: Presenilin-1 Antibody [NBP1-33611] - Paraffin-embedded U87 xenograft. Presenilin 1 antibody [C1C2], Internal dilution: 1:500.
Presenilin-1 Antibody

Immunocytochemistry/Immunofluorescence: Presenilin-1 Antibody [NBP1-33611] -

Immunocytochemistry/Immunofluorescence: Presenilin-1 Antibody [NBP1-33611] - HeLa cells were fixed in ice-cold MeOH for 5 min. Green: Presenilin 1 stained by Presenilin 1 antibody [C1C2], Internal diluted at 1:500.Blue: Hoechst 33342 staining. Scale bar= 10 um.
Presenilin-1 Antibody

Western Blot: Presenilin-1 Antibody [NBP1-33611] -

Western Blot: Presenilin-1 Antibody [NBP1-33611] - Wild-type (WT) and Presenilin 1 knockout (KO) HeLa cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Presenilin 1 antibody [C1C2], Internal diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Applications for Presenilin-1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris, 0.1M Glycine, 10% Glycerol

Format

BSA Free

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Presenilin-1

PSDR1 is a novel prostate short-chain dehydrogenase/reductase that exhibits increased expression on exposure to androgens in the LNCaP prostate cancer cell line. PSDR1 is expressed in normal and neoplastic prostate epithelium and is implicated in the pathogenesis of prostate carcinoma.

Alternate Names

Presenilin1, PSEN1, S182

Gene Symbol

PSEN1

Additional Presenilin-1 Products

Product Documents for Presenilin-1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Presenilin-1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Citations for Presenilin-1 Antibody - BSA Free

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Protocols

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FAQs

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