Presenilin-1: Products

Presenilin-1 (PS-1) and Presenilin-2 (PS-2) are integral membrane proteins that contain multiple transmembrane domains. Both are predominantly located within the endoplasmic reticulum (ER) and early Golgi apparatus.

"Presenilin-1" has 18 results in Products.
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DAPT 

Gamma γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

DBZ 

γ-secretase inhibitor; inhibits Notch pathway

DAPT 

DAPT synthesized to Ancillary Material Grade

BMS 299897 

Potent γ-secretase inhibitor

MRK 560 

γ-secretase inhibitor; attenuates amyloid plaque deposition

TC-E 5006 

γ-secretase modulator; reduces Aβ42 levels

PF 3084014 hydrobromide 

Potent γ-secretase inhibitor

Avagacestat 

Highly potent γ-secretase inhibitor; orally bioavailable

LY 450139 

γ-secretase pseudo-inhibitor

Proteome Profiler Human Protease Array Kit 

Contains 4 membranes - each spotted in duplicate with 35 different protease antibodies

Proteome Profiler Human Protease/Protease Inhibitor Array 

Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors
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