Propranolol hydrochloride

Catalog # Availability Size / Price Qty
Propranolol hydrochloride | CAS No. 318-98-9 | Non-selective Adrenergic beta Receptor Antagonists
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Description: β antagonist

Chemical Name: (RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride

Product Details
Citations (13)
Supplemental Products
Reviews (1)

Biological Activity

Propranolol hydrochloride is an β-adrenergic antagonist.

R-enantiomer, S-enantiomer and Glycol Metabolite also available.

Technical Data

Soluble to 100 mM in water
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Product Datasheets

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for Propranolol hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Propranolol hydrochloride include:

13 Citations: Showing 1 - 10

  1. A ventrolateral medulla-midline thalamic circuit for hypoglycemic feeding
    Authors: Beas Et al.
    Nat Commun  2020;11:6218
  2. Complex Formation between VEGFR2 and the β2-Adrenoceptor.
    Authors: Kilpatrick Et al.
    Cell Chem Biol  2019;26:830
  3. An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes.
    Authors: McKeithan Et al.
    Front Physiol  2017;8:766
  4. Negative cooperativity across β1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 β1-adrenoceptor binding conformation.
    Authors: Gherbi Et al.
    FASEB J  2015;29:2859
  5. Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of β-Adrenergic Receptors.
    Authors: Hansen and Manahan-Vaughan
    Mol Cancer  2015;25:1889
  6. Burn Induces Browning of the Subcutaneous White Adipose Tissue in Mice and Humans.
    Authors: Patsouris Et al.
    Cereb Cortex  2015;13:1538
  7. Application of BRET to monitor ligand binding to GPCRs.
    Authors: Stoddart Et al.
    Nat Methods  2015;12:661
  8. Chronic treatment with pra. or dulox. lessens concurrent anxiety-like behavior and alcohol intake: evidence of disrupted noradrenergic signaling in anxiety-related alcohol use.
    Authors: Skelly and Weiner
    Brain Behav  2014;4:468
  9. Medullary NE neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis.
    Authors: Bucher Et al.
    J Cereb Blood Flow Metab  2014;34:1128
  10. Detection of the secondary, low-affinity β1 -adrenoceptor site in living cells using the fluorescent CGP 12177 derivative BODIPY-TMR-CGP.
    Authors: Gherbi Et al.
    Br J Pharmacol  2014;171:5431


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Propranolol hydrochroride treated postnatal mice decreased PI3K activity in heart
By YANCHUN XU on 01/05/2018
Application: Species: Mouse

We used Propranolol hydrochroride (cat#0624) to treat postnatal mice to investigate the PI3K activity change

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