Catalog Number: 0624
Chemical Name: (RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride
Biological Activity
β-adrenergic antagonist.

R-enantiomer, S-enantiomer and Glycol Metabolite also available.

Technical Data
  • M.Wt:
    295.81
  • Formula:
    C16H21NO2.HCl
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Store at RT
  • CAS No:
    3506-09-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References

  1. Kishimoto T et al.
    Leucocyte Typing VI. Garland Publishing Inc. London.
  2. Effects of propranolol treatment on left ventricular function and intracellular calcium regulation in rats with postinfarction heart failure.
    Litwin et al.
    Br.J.Pharmacol., 1999;127:1671
  3. The inhibitory effect of propranolol on ATP-sensitive potassium channels in neonatal rat heart.
    Xie et al.
    Br.J.Pharmacol., 1998;123:599
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Propranolol hydrochloride include:

9 Citations: Showing 1 - 9
Filter your results:

  1. Negative cooperativity across β1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 β1-adrenoceptor binding conformation.
    Authors: Gherbi Et al.
    FASEB J 2015;29:2859
  2. Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of β-Adrenergic Receptors.
    Authors: Hansen and Manahan-Vaughan
    Mol Cancer 2015;25:1889
  3. Burn Induces Browning of the Subcutaneous White Adipose Tissue in Mice and Humans.
    Authors: Patsouris Et al.
    Cereb Cortex 2015;13:1538
  4. Application of BRET to monitor ligand binding to GPCRs.
    Authors: Stoddart Et al.
    Nat Methods 2015;12:661
  5. Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis.
    Authors: Bucher Et al.
    J Cereb Blood Flow Metab 2014;34:1128
  6. Detection of the secondary, low-affinity β1 -adrenoceptor site in living cells using the fluorescent CGP 12177 derivative BODIPY-TMR-CGP.
    Authors: Gherbi Et al.
    Br J Pharmacol 2014;171:5431
  7. Modulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neurons.
    Authors: Rankovic Et al.
    PLoS One 2011;6:e27474
  8. β1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons.
    Authors: Meitzen Et al.
    J Neurochem 2011;116:984
  9. Catecholamine up-regulates MMP-7 expression by activating AP-1 and STAT3 in gastric cancer.
    Authors: Shi Et al.
    Purinergic Signal 2010;9:269
Tocris Small Molecules
Description Application Cat# Citations Images  

(S)-(-)-Propranolol hydrochloride

0834 1  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

(R)-(+)-Propranolol hydrochloride

0835  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Propranolol glycol

0851  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Have you used Propranolol hydrochloride?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Feedback

Customer Information