Catalog Number: 4333
Chemical Name: 4-Thiouridine-5'-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt
Biological Activity
Potent, selective P2Y2 agonist (EC50 = 0.134 μM). Displays >60-fold selectivity versus P2Y4 and P2Y6 receptors.
Technical Data
  • M.Wt:
    622.14
  • Formula:
    C10H11F2N2Na4O13P3S
  • Solubility:
    Soluble in water (supplied pre-dissolved at a concentration of 10mM)
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    1657025-60-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors.
    El-Tayeb et al.
    J.Med.Chem., 2011;54:2878
Citations:

The citations listed below are publications that use Tocris products. Selected citations for PSB 1114 include:

1 Citations: Showing 1 - 1

  1. ATP acting through P2Y receptors causes activation of podocyte TRPC6 channels: role of podocin and reactive oxygen species.
    Authors: Roshanravan and Dryer
    Neuropsychopharmacology 2014;306:F1088

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