PSMB7 (proteasome subunit, beta-type 7), also called proteasome subunit Z, is a widely expressed, non-catalytic component of the 20S proteasome core within the 26S proteasome that stabilizes late stages of proteasome assembly. Human PSMB7 is synthesized as a 277 amino acid (aa) protein with a 43 aa propeptide and a 234 active protein that contains one potential tyrosine phosphorylation site. Total PSMB7 expression is positively correlated with chemotherapy resistance in human breast cancer.
PSMB7 Antibody (787807) [Biotin]
Novus Biologicals | Catalog # FAB7590B
Key Product Details
Species Reactivity
Human, Mouse
Applications
Western Blot
Label
Biotin
Antibody Source
Monoclonal Mouse IgG1 Clone # 787807
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Product Specifications
Immunogen
E. coli-derived recombinant human PSMB7
Thr44-Ser277
Accession # Q99436
Thr44-Ser277
Accession # Q99436
Specificity
Detects human PSMB7 in direct ELISAs.
In direct ELISAs, no cross-reactivity
with recombinant human PSMB10 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for PSMB7 Antibody (787807) [Biotin]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: PSMB7
Long Name
Proteasome (Prosome, Macropain) Subunit, beta Type, 7
Alternate Names
Macropain Chain Z, Proteasome Subunit Z
Gene Symbol
PSMB7
Additional PSMB7 Products
Product Documents for PSMB7 Antibody (787807) [Biotin]
Product Specific Notices for PSMB7 Antibody (787807) [Biotin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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