PSMB7 Antibody

Novus Biologicals | Catalog # NBP1-52081

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all PSMB7 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RNAVLEADFAKR corresponding to internal region according to NP_002790.1.

Epitope

C-RNAVLEADFAKR

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

Novus Biologicals Goat PSMB7 Antibody (NBP1-52081) is a polyclonal antibody validated for use in WB and ELISA. Anti-PSMB7 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for PSMB7 Antibody

Western Blot: PSMB7 Antibody [NBP1-52081]

Western Blot: PSMB7 Antibody [NBP1-52081]

Western Blot: Proteasome 20S beta 7 Antibody [NBP1-52081] - NBP1-52081 (0.3ug/ml) staining of HEK293 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for PSMB7 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 40 kDa band observed in lysates of HEK 293, HeLa and Jurkat and of mouse Fetal brain (calculated MW of 30.0 kDa band according to NP_002790.1). The observed molecular weight corresponds to earlier findings with different antibodies from other sources.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PSMB7

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).

Long Name

Proteasome (Prosome, Macropain) Subunit, beta Type, 7

Alternate Names

Macropain Chain Z, Proteasome Subunit Z

Entrez Gene IDs

5695 (Human); 19177 (Mouse); 85492 (Rat)

Gene Symbol

PSMB7

UniProt

NP_002790.1 (Human)

Additional PSMB7 Products

Product Documents for PSMB7 Antibody

Certificate of Analysis

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Download SDS

Product Specific Notices for PSMB7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Biomarkers

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