Rat CCL26-like/Eotaxin-3-like Alexa Fluor® 488-conjugated Antibody

Catalog #: AF3878G Datasheet / COA / SDS

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AF3878G-100UG

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Rat CCL26-like/Eotaxin-3-like Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Rat

Specificity

Detects rat CCL26-like/Eotaxin‑3-like in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse CCL26-like is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant rat CCL26-like/Eotaxinâ€‘3-like
Thr24-Trp94
Accession # NP_001102958

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CCL26-like/Eotaxin-3-like

Chemokine (CC motif) ligand 26, also known as Eotaxin 3, is a human CC chemokine ligand that binds and signals via the chemokine receptor CCR3. Rat CCL26‑like/Eotaxin 3-like is an 8.5 kDa orthologue of the human CCL26/eotaxin 3. It is a 94 amino acid (aa) residue protein with a 23 aa signal sequence and a 71 aa mature segment. It is presumed that rat CCL26-like/Eotaxin 3-like will bind CCR3 to induce eosinophil chemotaxis and transendothelial migration. Mature rat CCL26 shares 48%, 63%, and 48% aa sequence identity with the human, mouse and canine CCL26/Eotaxin 3, respectively.

Alternate Names

CCL26 like; CCL26-like; Eotaxin-3-like; GPRC1A;GRM1;Metabotropic glutamate receptor 1;MGLU1;MGLUR1;PPP1R85;SCA44;SCAR13