Rat CXCR3 PE-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB8109P
Detection of CXCR3 in Rat Splenocytes by Flow Cytometry.
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Rat CXCR3 PE-conjugated Antibody Summary

Species Reactivity
Rat
Specificity
Detects rat CXCR3 in direct ELISAs. Stains rat CXCR3 transfected cells but not irrelevant transfectants.
Source
Monoclonal Mouse IgG2B Clone # 868013
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
NS0 mouse myeloma cell line transfected with rat CXCR3
Accession # Q9J119
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Phycoerythrin

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Flow Cytometry Detection of CXCR3 in Rat Splenocytes by Flow Cytometry. View Larger

Detection of CXCR3 in Rat Splenocytes by Flow Cytometry. Rat splenocytes were stained with anti-rat CD4 APC‑conjugated antibody and either (A) Mouse Anti-Rat CXCR3 PE‑conjugated Monoclonal Antibody (Catalog # FAB8109P) or (B) Mouse IgG2B Phycoerythrin Isotype Control (Catalog # IC0041P). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CXCR3

CXCR3, also known as CD183, is an approximately 41 kDa (predicted) 7-transmembrane spanning receptor for the chemokines CXCL9, CXCL10, and CXCL11. It is expressed on activated T cells, B cells, and NK cells during inflammation. It is additionally upregulated on solid tumor cells, tumor endothelium, and cancer stem cells. CXCR3 plays a role in leukocyte recruitment to sites of inflammation. It also contributes to Th1 biased responses during autoimune diseases rheumatoid arthritis, systemic erythematosis, and type 1 diabetes. Rat CXCR3 shares 86% and 96% amino acid sequence identity with human and mouse CXCR3, respectively.

Entrez Gene IDs
2833 (Human); 12766 (Mouse); 84475 (Rat)
Alternate Names
CD183 antigen; CD183; chemokine (C-X-C motif) receptor 3; chemokine (C-X-C) receptor 3; CKR-L2IP-10 receptor; CMKAR3; C-X-C chemokine receptor type 3; CXCR3; CXC-R3; CXCR-3; G protein-coupled receptor 9CD182; GPR9; GPR9Mig-R; Interferon-inducible protein 10 receptor; IP10 receptor; IP10-R; Mig receptor; MigR

Product Datasheets

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