RCGD 423

Key Product Details

Product Description

RCGD 423 is a gp130 modulator. Binds gp130, promotes Myc expression, increases lactate production and activates downstream JAK/STAT signaling pathways in hair follicle stem cells. Also increases articular chondrocyte activation and facilitates joint repair by regulating cartilage growth and differentiation.

Product Specifications for RCGD 423

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for RCGD 423

The following data is based on the product molecular weight 331.23.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.02 mL	15.10 mL	30.19 mL
5 mM	0.60 mL	3.02 mL	6.04 mL
10 mM	0.30 mL	1.51 mL	3.02 mL
50 mM	0.06 mL	0.30 mL	0.60 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Alam A small molecule mimetic of the humanin peptide as a candidate for modulating NMDA-induced neurotoxicity. ACS.Chem.Neurosci. 2018 PMID: 29161500
• Flores Lactate dehydrogenase activity drives hair follicle stem cell activation. Nat.Cell Biol. 2017 PMID: 28812580

Product Documents for RCGD 423