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425 results for "gp130" in Products
gp130 Products
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.
| Reactivity: | Human |
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| Reactivity: | Human |
| Sensitivity: | 0.05 ng/mL (Cell Culture Supernates) 0.08 ng/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Assay Range: | 0.125-8 ng/mL (Cell Culture Supernates) 0.25-16 ng/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Applications: | ELISA |
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| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | P40189 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, B/N |
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| Reactivity: | Human |
| Source: | Sf 21 (baculovirus) |
| Accession #: | P40189 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #28126 |
| Applications: | B/N, Flow, CyTOF-ready |
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| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #125623 |
| Applications: | Flow, ICC/IF, CyTOF-ready |
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #28105 |
| Applications: | IHC, ELISA(Cap), B/N |
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| Reactivity: | Mouse |
| Source: | NS0 |
| Accession #: | Q6PDI9 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Assay Range: | 156-10000 pg/mL |
| Applications: | ELISA |
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #29104 |
| Applications: | ELISA |
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| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #125605 |
| Applications: | ELISA(Cap), B/N |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready |
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| Reactivity: | Mouse |
| Assay Range: | 125-8000 pg/mL |
| Applications: | ELISA |
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| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #745314 |
| Applications: | WB, Flow, CyTOF-ready |
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| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: gp130/CD130 Antibody [NBP2-15776]](https://resources.rndsystems.com/images/products/gp130-CD130-Antibody-Western-Blot-NBP2-15776-img0009.jpg "Western Blot: gp130/CD130 Antibody [NBP2-15776]")
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #28126 |
| Applications: | Flow |
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Biotinylated
| Reactivity: | Human |
| Source: | HEK293 |
| Accession #: | AAA59155.1 |
| Applications: | Bioactivity |
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| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #125623 |
| Applications: | Flow |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, B/N |
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| Reactivity: | Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
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gp130 inhibitor; blocks cytokine-triggered gp130 signaling
| Chemical Name: | 2-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl) 2-pyrazinecarboxylic acid hydrazide hydrochloride |
| Purity: | ≥98% |
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| Reactivity: | Human |
| Source: | HEK293 |
| Accession #: | AAA59155.1 |
| Applications: | Bioactivity |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: gp130/CD130 AntibodyAzide and BSA Free [NBP3-03789]](https://resources.rndsystems.com/images/products/gp130-CD130%20Antibody-Western%20Blot-NBP3-03789-img0004.jpg "Western Blot: gp130/CD130 AntibodyAzide and BSA Free [NBP3-03789]")
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| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #125604 |
| Applications: | WB |
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