Recombinant Human CD79A Protein, CF

R&D Systems | Catalog # 9685-CD

R&D Systems
100% Guarantee

Key Product Details

  • R&D Systems NS0-derived Recombinant Human CD79A Protein (9685-CD)
  • Quality control testing to verify active proteins with lot specific assays by in-house scientists
  • All R&D Systems proteins are covered with a 100% guarantee

Source

NS0

Accession Number

P11912-1
View all CD79A Proteins and Enzymes »

Product Specifications

Source

Mouse myeloma cell line, NS0-derived human CD79A protein
Leu33-Arg143, with a C-terminal 6-His tag

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

Endotoxin Level

<0.10 EU per 1 μg of the protein by the LAL method.

N-terminal Sequence Analysis

Leu33

Predicted Molecular Mass

13 kDa

SDS-PAGE

38-43 kDa, reducing conditions

Activity

Bioassay data are not available.

Scientific Data Images for Recombinant Human CD79A Protein, CF

Recombinant Human CD79A Protein SDS-PAGE

Recombinant Human CD79A Protein SDS-PAGE

2 μg/lane of Recombinant Human CD79A was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® blue staining, showing bands at 38 - 43 kDa.

Formulation, Preparation, and Storage

9685-CD
Formulation Lyophilized from a 0.2 μm filtered solution in PBS and EDTA.
Reconstitution

Reconstitute at 250 μg/mL in PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background: CD79A

CD79A (also known as Mb-1, Ig alpha and B cell antigen receptor complex-associated protein alpha-chain) is a 30-40 kDa member of the Ig-Superfamily. It is expressed on B cells, and forms a covalent heterodimer with CD79B. Heterodimers of CD79A and CD79B interacts noncovalently with membrane Ig, forming the B cell antigen receptor (BCR) (1). Within this complex, membrane Ig detects antigen while CD79AB initiates signaling (1). CD79A is essential for the differentiation of pre-B cells, and the pre-BCR regulates the surface expression of IL-7R (2). Mature human CD79A is a type I transmembrane glycoprotein. It contains an extracellular region (aa 33-143) with one C2-type Ig-like domain (aa 33-116), and an ITAM-containing cytoplasmic domain (aa 177-205) (3). Within the ECD, human CD79A shares 57% amino acid sequence identity with mouse and rat CD79A.

References

  1. Tseng, J. et al. (1997) Blood, 89:1513.
  2. Kurosaki, T. (2000) Current opinion in immunology, 12:276.
  3. Radaev, Sergei et al. (2010) Structure 18:934.

Alternate Names

CD79A, MB-1

Entrez Gene IDs

973 (Human); 12518 (Mouse); 681236 (Rat); 722190 (Rhesus Macaque)

Gene Symbol

CD79A

UniProt

P11912-1

Additional CD79A Products

Product Documents for Recombinant Human CD79A Protein, CF

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Recombinant Human CD79A Protein, CF

For research use only

Related Research Areas

B Cell Activation

Customer Reviews for Recombinant Human CD79A Protein, CF

There are currently no reviews for this product. Be the first to review Recombinant Human CD79A Protein, CF and earn rewards!

Have you used Recombinant Human CD79A Protein, CF?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

FAQs

No product specific FAQs exist for this product.

View all FAQs for Proteins and Enzymes