IFN-beta (Interferon-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.
Recombinant Human IFN-beta 1a (Mammalian) Protein
R&D Systems | Catalog # 11415-1
New Version Available:
8499-IF
NEW
A New rh IFN-beta is Available! It has lower endotoxin specifications, is made in-house, and is priced competitively!
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Key Product Details
- R&D Systems CHO-derived Recombinant Human IFN-beta 1a (Mammalian) Protein (11415-1)
- Quality control testing to verify active proteins with lot specific assays by in-house scientists
- All R&D Systems proteins are covered with a 100% guarantee
Source
CHO
Accession Number
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Formulation, Preparation, and Storage
11415-1
| Shipping | The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
Background: IFN-beta
Long Name
Interferon beta
Alternate Names
IFB, IFF, IFNB, IFNB1, IFNbeta
Gene Symbol
IFNB1
UniProt
Additional IFN-beta Products
Product Documents for Recombinant Human IFN-beta 1a (Mammalian) Protein
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Recombinant Human IFN-beta 1a (Mammalian) Protein
For research use only
Citations for Recombinant Human IFN-beta 1a (Mammalian) Protein
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FAQs for Recombinant Human IFN-beta 1a (Mammalian) Protein
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Q: Why is recombinant Human Interferon-beta 1a (Catalog #'s 11415-1 and 11410-2) formulated with acetic acid?
A: Acetic acid was added to prevent aggregation.
