Recombinant Human/Mouse/Rat Activin A Protein

GMP Version Available: 338-GMP
GMP
CHO derived

Carrier Free

Catalog # Availability Size / Price Qty
338-AC-010/CF
338-AC-050/CF
338-AC-01M/CF
338-AC-500/CF

With Carrier

Catalog # Availability Size / Price Qty
338-AC-010
338-AC-050
338-AC-01M
338-AC-500
Recombinant Human/Mouse/Rat Activin A Protein Bioactivity
3 Images
Product Details
Citations (441)
FAQs
Supplemental Products
Reviews (12)

Recombinant Human/Mouse/Rat Activin A Protein Summary

Product Specifications

Purity
>95%, by SDS-PAGE with silver staining.
Endotoxin Level
<0.01 EU per 1 μg of the protein by the LAL method.
Activity
Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340. The ED50 for this effect is 0.2‑1.2 ng/mL.
The specific activity of Recombinant Human/Mouse/Rat Activin A is approximately 2.5 x 103 units/mg, which is calibrated against human Activin A WHO International Standard (NIBSC code: 91/626).   Specific activity is for reference purposes only and is not routinely tested.  
Source
Chinese Hamster Ovary cell line, CHO-derived Activin A protein
Gly311-Ser426
Accession #
N-terminal Sequence
Analysis
Gly311
Structure / Form
Disulfide-linked homodimer
Predicted Molecular Mass
13 kDa (monomer)
SDS-PAGE
14 kDa, reducing conditions
24 kDa, non-reducing conditions

Product Datasheets

338-AC (with carrier)

338-AC/CF (carrier free)

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

338-AC

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Reconstitution Reconstitute at 100-500 μg/mL in sterile 4 mM HCl.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

338-AC/CF

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Reconstitution Reconstitute at 100-500 µg/mL in sterile 4 mM HCl.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Data Images

Bioactivity Recombinant Human/Mouse/Rat Activin A Protein Bioactivity View Larger

Recombinant Human/Mouse/Rat Activin A (Catalog # 338-AC) induces hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50 is 0.2‑1.2 ng/mL.

SDS-PAGE Recombinant Human/Mouse/Rat Activin A Protein SDS-PAGE View Larger

1 μg/lane of Recombinant Human/Mouse/Rat Activin A was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing single bands at 14 kDa and 24 kDa, respectively.

Bioactivity Recombinant Human/Mouse/Rat Activin A Promotes the Differentiation of Pluripotent Stem Cells into Endoderm. View Larger

BG01V human embryonic stem cells were differentiated into endoderm using media supplemented with Recombinant Human/Mouse/Rat Activin A (Catalog # 338-AC). Control cells were cultured in medium without recombinant Activin A. Differentiation into endoderm was confirmed by positive-staining for Claudin-6 (red) and Sox17 (green) using the Mouse Anti-Human Claudin-6 Monoclonal Antibody (Catalog # MAB3656) and the Goat Anti-Human Sox17 Polyclonal Antibody (Catalog # AF1924), respectively. BG01V human embryonic stem cells are licensed from ViaCyte, Inc.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Activin A

Activin and Inhibin are members of the TGF-beta superfamily of cytokines and are involved in a wide range of biological processes including tissue morphogenesis and repair, fibrosis, inflammation, neural development, hematopoiesis, reproductive system function, and carcinogenesis (1‑7). Activin and Inhibin are produced as precursor proteins. Their amino terminal propeptides are proteolytically cleaved and facilitate formation of disulfide-linked dimers of the bioactive proteins (8, 9). Activins are nonglycosylated homodimers or heterodimers of various beta subunits ( beta A, beta B, beta C, and beta E in mammals), while Inhibins are heterodimers of a unique alpha subunit and one of the beta subunits. Activin A is a widely expressed homodimer of two beta A chains. The beta A subunit can also heterodimerize with a beta B or beta C subunit to form Activin AB and Activin AC, respectively (10). The 14 kDa mature human beta A chain shares 100% amino acid sequence identity with bovine, feline, mouse, porcine, and rat beta A. Activin A exerts its biological activities by binding to the type 2 serine/threonine kinase Activin RIIA which then noncovalently associates with the type 1 serine/threonine kinase Activin RIB/ALK-4 (7, 11). Signaling through this receptor complex leads to Smad activation and regulation of activin-responsive gene transcription (7, 11). The bioactivity of Activin A is regulated by a variety of mechanisms (11). BAMBI, Betaglycan, and Cripto are cell‑associated molecules that function as decoy receptors or limit the ability of Activin A to induce receptor complex assembly (12‑14). The intracellular formation of Activin A can be prevented by the incorporation of the beta A subunit into Activin AC or Inhibin A (3, 10). And the bioavailability of Activin A is restricted by its incorporation into inactive complexes with alpha 2-Macroglobulin, Follistatin, and FLRG (15, 16).

References
  1. Kumanov, P. et al. (2005) Reprod. Biomed. Online 10:786.
  2. Maeshima, A. et al. (2008) Endocr. J. 55:1.
  3. Rodgarkia-Dara, C. et al. (2006) Mutat. Res. 613:123.
  4. Werner, S. and C. Alzheimer (2006) Cytokine Growth Factor Rev. 17:157.
  5. Xu, P. and A.K. Hall (2006) Dev. Biol. 299:303.
  6. Shav-Tal, Y. and D. Zipori (2002) Stem Cells 20:493.
  7. Chen, Y.G. et al. (2006) Exp. Biol. Med. 231:534.
  8. Gray, A.M. and A.J. Mason (1990) Science 247:1328.
  9. Mason, A.J. et al. (1996) Mol. Endocrinol. 10:1055.
  10. Thompson, T.B. et al. (2004) Mol. Cell. Endocrinol. 225:9.
  11. Harrison, C.A. et al. (2005) Trends Endocrinol. Metab. 16:73.
  12. Onichtchouk, D. et al. (1999) Nature 401:480.
  13. Gray, P.C. et al. (2002) Mol. Cell. Endocrinol. 188:254.
  14. Kelber, J.A. et al. (2008) J. Biol. Chem. 283:4490.
  15. Phillips, D.J. et al. (1997) J. Endocrinol. 155:65.
  16. Schneyer, A. et al. (2003) Endocrinology 144:1671.
Entrez Gene IDs
3624 (Human); 16323 (Mouse); 29200 (Rat)
Alternate Names
Activin A; activin AB alpha polypeptide; Activin beta-A chain; erythroid differentiation factor; Erythroid differentiation protein; follicle-stimulating hormone-releasing protein; FSH-releasing protein; inhibin beta A chain; inhibin beta A subunit; Inhibin, beta-1

Citations for Recombinant Human/Mouse/Rat Activin A Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

441 Citations: Showing 1 - 10
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  1. Kinase inhibitor-induced cardiotoxicity assessed in vitro with human pluripotent stem cell derived cardiomyocytes
    Authors: HQ Xian, C Blanco, K Bonham, HR Snodgrass
    Toxicology and Applied Pharmacology, 2022;437(0):115886.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Transplantation of a human induced pluripotent stem cell-derived airway epithelial cell sheet into the middle ear of rats
    Authors: T Tada, H Ohnishi, N Yamamoto, F Kuwata, Y Hayashi, H Okuyama, T Morino, Y Kasai, H Kojima, K Omori
    Regenerative Therapy, 2022;19(0):77-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Orally-active, clinically-translatable senolytics restore alpha-Klotho in mice and humans
    Authors: Y Zhu, LGPL Prata, EOW Gerdes, JME Netto, T Pirtskhala, N Giorgadze, U Tripathi, CL Inman, KO Johnson, A Xue, AK Palmer, T Chen, K Schaefer, JN Justice, AM Nambiar, N Musi, SB Kritchevsk, J Chen, S Khosla, D Jurk, MJ Schafer, T Tchkonia, JL Kirkland
    EBioMedicine, 2022;0(0):103912.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  4. 3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T�cells
    Authors: Z Wang, HP McWilliams, H Reza, JR Ostberg, W Chen, X Wang, C Huynh, V Vyas, WC Chang, R Starr, JR Wagner, B Aguilar, X Yang, X Wu, J Wang, W Chen, E Koelker-Wo, CS Seet, A Montel-Hag, GM Crooks, SJ Forman, CE Brown
    Cell Stem Cell, 2022;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Cardiac fibrosis models using human induced pluripotent stem cell-derived cardiac tissues allow anti-fibrotic drug screening in vitro
    Authors: H Iseoka, S Miyagawa, Y Sakai, Y Sawa
    Stem Cell Research, 2021;54(0):102420.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Effects of selected hormones and their combination on progesterone and estradiol production and proliferation of feline granulosa cells cultured in�vitro
    Authors: M Chiara Per, N Bellitto, ERS Maylem, F Caloni, LJ Spicer
    Theriogenology, 2021;168(0):1-12.
    Species: Feline
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Derivation of Mouse Parthenogenetic Advanced Stem Cells
    Authors: M Wei, J Zhang, J Liu, C Zhao, S Cao, X Yan, B Wu, S Bao
    International Journal of Molecular Sciences, 2021;22(16):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Improving In Vitro Culture of Human Male Fetal Germ Cells
    Authors: M Martin-Ina, M Ferreira, J Taelman, C Eguizabal, SM Chuva De S
    Cells, 2021;10(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Role of stromal activin A in human pancreatic cancer and metastasis in mice
    Authors: G Mancinelli, C Torres, N Krett, J Bauer, K Castellano, R McKinney, D Dawson, G Guzman, R Hwang, S Grimaldo, P Grippo, B Jung
    Scientific Reports, 2021;11(1):7986.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Generation of insulin-producing pancreatic beta cells from multiple human stem cell lines
    Authors: NJ Hogrebe, KG Maxwell, P Augsornwor, JR Millman
    Nature Protocols, 2021;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes
    Authors: T Grancharov, KA Gerbin, AB Rosenberg, CM Roco, JE Arakaki, CM DeLizo, SQ Dinh, RM Donovan-Ma, M Hirano, AM Nelson, J Tang, JA Theriot, C Yan, V Menon, SP Palecek, G Seelig, RN Gunawardan
    Scientific Reports, 2021;11(1):15845.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes
    Authors: K Sattler, I El-Battraw, L Cyganek, S Lang, H Lan, X Li, Z Zhao, J Utikal, T Wieland, M Borggrefe, X Zhou, I Akin
    Scientific Reports, 2021;11(1):14689.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  13. miR-27b antagonizes BMP signaling in early differentiation of human induced pluripotent stem cells
    Authors: J Lim, E Sakai, F Sakurai, H Mizuguchi
    Scientific Reports, 2021;11(1):19820.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Development of a quantitative prediction algorithm for target organ-specific similarity of human pluripotent stem cell-derived organoids and cells
    Authors: MO Lee, SG Lee, CR Jung, YS Son, JW Ryu, KB Jung, JH Ahn, JH Oh, HA Lee, JH Lim, J Kim, I Jang, J Choi, J Jung, K Park, B Lee, DS Kim, MY Son, HS Cho
    Nature Communications, 2021;12(1):4492.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Capturing human trophoblast development with naive pluripotent stem cells in�vitro
    Authors: S Io, M Kabata, Y Iemura, K Semi, N Morone, A Minagawa, B Wang, I Okamoto, T Nakamura, Y Kojima, C Iwatani, H Tsuchiya, B Kaswandy, E Kondoh, S Kaneko, K Woltjen, M Saitou, T Yamamoto, M Mandai, Y Takashima
    Cell Stem Cell, 2021;28(6):1023-1039.e13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  16. The development of a functional human small intestinal epithelium model for drug absorption
    Authors: O Kwon, KB Jung, KR Lee, YS Son, H Lee, JJ Kim, K Kim, S Lee, YK Song, J Jung, K Park, DS Kim, MJ Son, MO Lee, TS Han, HS Cho, SJ Oh, H Chung, SH Kim, KS Chung, J Kim, CR Jung, MY Son
    Science Advances, 2021;7(23):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Oxygen Is an Ambivalent Factor for the Differentiation of Human Pluripotent Stem Cells in Cardiac 2D Monolayer and 3D Cardiac Spheroids
    Authors: M Souidi, Y Sleiman, I Acimovic, J Pribyl, A Charrabi, V Baecker, V Scheuerman, M Pesl, S Jelinkova, P Skladal, P Dvorak, A Lacampagne, V Rotrekl, AC Meli
    International Journal of Molecular Sciences, 2021;22(2):.
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  18. Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
    Authors: S Funakoshi, I Fernandes, O Mastikhina, D Wilkinson, T Tran, W Dhahri, A Mazine, D Yang, B Burnett, J Lee, S Protze, GD Bader, SS Nunes, M Laflamme, G Keller
    Nature Communications, 2021;12(1):3155.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  19. Adhesion GPCR Latrophilin-2 Specifies Cardiac Lineage Commitment through CDK5, Src, and P38MAPK
    Authors: CS Lee, HJ Cho, JW Lee, H Son, J Chai, HS Kim
    Stem Cell Reports, 2021;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Two distinct trophectoderm lineage stem cells from human pluripotent stem cells
    Authors: A Mischler, V Karakis, J Mahinthaku, CK Carberry, A San Miguel, JE Rager, RC Fry, BM Rao
    The Journal of Biological Chemistry, 2021;0(0):100386.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Sex-Specific Isolation and Propagation of Human Premeiotic Fetal Germ Cells and Germ Cell-Like Cells
    Authors: S Mishra, J Taelman, YW Chang, A Boel, P De Sutter, B Heindryckx, SM Chuva De S
    Cells, 2021;10(5):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  22. The in vitro multilineage differentiation and maturation of lung and airway cells from human pluripotent stem cell-derived lung progenitors in 3D
    Authors: AL Rodrigues, HY Liu, YW Chen, M Porotto, A Moscona, HW Snoeck
    Nature Protocols, 2021;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Reduced gonadotroph stimulation by ethanolamine plasmalogens in old bovine brains
    Authors: H Kadokawa, M Kotaniguch, O Kereilwe, S Kitamura
    Scientific Reports, 2021;11(1):4757.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Heterozygous APC germline mutations impart predisposition to colorectal cancer
    Authors: L Preisler, A Habib, G Shapira, L Kuznitsov-, Y Mayshar, I Carmel-Gro, M Malcov, F Azem, N Shomron, R Kariv, D Hershkovit, D Ben-Yosef
    Scientific Reports, 2021;11(1):5113.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Retinoic acid regulates erythropoietin production cooperatively with hypoxia-inducible factors in human iPSC-derived erythropoietin-producing cells
    Authors: N Katagiri, H Hitomi, SI Mae, M Kotaka, L Lei, T Yamamoto, A Nishiyama, K Osafune
    Scientific Reports, 2021;11(1):3936.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models
    Authors: Y Aghazadeh, F Poon, F Sarangi, FTM Wong, ST Khan, X Sun, R Hatkar, BJ Cox, SS Nunes, MC Nostro
    Cell Stem Cell, 2021;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
    Authors: AV Parent, G Faleo, J Chavez, M Saxton, DI Berrios, NR Kerper, Q Tang, M Hebrok
    Cell Reports, 2021;36(7):109538.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Modulating mesendoderm competence during human germ layer differentiation
    Authors: JR Valcourt, RE Huang, S Kundu, D Venkatasub, RE Kingston, S Ramanathan
    Cell Reports, 2021;37(6):109990.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Chemically Defined Conditions Mediate an Efficient Induction of Dental Pulp Pluripotent-Like Stem Cells into Hepatocyte-Like Cells
    Authors: C Gil-Recio, S Montori, S Al Demour, MA Ababneh, E Ferrés-Pad, C Marti, E Ferrés-Ama, M Barajas, A Al Madhoun, M Atari
    Stem Cells International, 2021;2021(0):5212852.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes
    Authors: PP Shah, W Lv, JH Rhoades, A Poleshko, D Abbey, MA Caporizzo, R Linares-Sa, JG Heffler, N Sayed, D Thomas, Q Wang, LJ Stanton, K Bedi, MP Morley, TP Cappola, AT Owens, KB Margulies, DB Frank, JC Wu, DJ Rader, W Yang, BL Prosser, K Musunuru, R Jain
    Cell Stem Cell, 2021;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis
    Authors: CL Wu, A Dicks, N Steward, R Tang, DB Katz, YR Choi, F Guilak
    Nature Communications, 2021;12(1):362.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  32. PGC7 promotes tumor oncogenic dedifferentiation through remodeling DNA methylation pattern for key developmental transcription factors
    Authors: Q Yan, Y Zhang, X Fang, B Liu, TL Wong, L Gong, S Liu, D Yu, M Liu, L Jiang, X Wang, T Wei, Y Jia, L Li, L Sun, Y Tang, N Zhou, YF Yuan, Y Li, S Ma, XY Guan
    Cell Death and Differentiation, 2021;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients
    Authors: AF de Souza, FF Bressan, NCG Pieri, RC Botigelli, T Revay, SK Haddad, DT Covas, ES Ramos, WA King, FV Meirelles
    Cells, 2021;10(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage
    Authors: V Chesnokova, S Zonis, A Apostolou, HQ Estrada, S Knott, K Wawrowsky, K Michelsen, A Ben-Shlomo, R Barrett, V Gorbunova, K Karalis, S Melmed
    Cell Reports, 2021;37(11):110068.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals
    Authors: C Schaniel, P Dhanan, B Hu, Y Xiong, T Raghunanda, DM Gonzalez, R Dariolli, SL D'Souza, AS Yadaw, J Hansen, G Jayaraman, B Mathew, M Machado, SI Berger, J Tripodig, V Najfeld, J Garg, M Miller, CS Surlyn, KC Michelis, NC Tangirala, H Weerahandi, DC Thomas, KG Beaumont, R Sebra, M Mahajan, E Schadt, D Vidovic, SC Schürer, J Goldfarb, EU Azeloglu, MR Birtwistle, EA Sobie, JC Kovacic, NC Dubois, R Iyengar
    Stem Cell Reports, 2021;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells
    Authors: F Xu, C Deng, Z Ren, L Sun, Y Meng, W Liu, J Wan, G Chen
    Cell Reports, 2021;37(9):110063.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. An airway organoid-based screen identifies a role for the HIF1alpha-glycolysis axis in SARS-CoV-2 infection
    Authors: X Duan, X Tang, MS Nair, T Zhang, Y Qiu, W Zhang, P Wang, Y Huang, J Xiang, H Wang, RE Schwartz, DD Ho, T Evans, S Chen
    Cell Reports, 2021;37(6):109920.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells
    Authors: H Fang, S Geng, M Hao, Q Chen, M Liu, C Liu, Z Tian, C Wang, T Takebe, JL Guan, Y Chen, Z Guo, W He, J Diao
    Nature Communications, 2021;12(1):109.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo
    Authors: JOR Hernandez, X Wang, M Vazquez-Se, M Lopez-Marf, MF Sobral-Rey, A Moran-Horo, M Sundberg, DO Lopez-Cant, CK Probst, GU Ruiz-Espar, K Giannikou, R Abdi, EP Henske, DJ Kwiatkowsk, M Sahin, DR Lemos
    Nature Communications, 2021;12(1):6496.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors
    Authors: RJ Geusz, A Wang, DK Lam, NK Vinckier, KD Alysandrat, DA Roberts, J Wang, S Kefalopoul, A Ramirez, Y Qiu, J Chiou, KJ Gaulton, B Ren, DN Kotton, M Sander
    Nature Communications, 2021;12(1):6636.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis
    Authors: R Ungricht, L Guibbal, MC Lasbennes, V Orsini, M Beibel, A Waldt, R Cuttat, W Carbone, A Basler, G Roma, F Nigsch, JS Tchorz, D Hoepfner, PS Hoppe
    Cell Stem Cell, 2021;0(0):.
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  42. Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation
    Authors: Y Lan, KM Banks, H Pan, N Verma, GR Dixon, T Zhou, B Ding, O Elemento, S Chen, D Huangfu, T Evans
    Cell Reports, 2021;37(10):110095.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids
    Authors: S Xia, Z Bozóky, M Di Paola, O Laselva, S Ahmadi, JX Jiang, AL Pitstick, C Jiang, D Rotin, CN Mayhew, NL Jones, CE Bear
    Cells, 2021;10(12):.
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  44. Auto/paracrine factors and early Wnt inhibition promote cardiomyocyte differentiation from human induced pluripotent stem cells at initial low cell density
    Authors: MNT Le, M Takahi, K Ohnuma
    Scientific Reports, 2021;11(1):21426.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model
    Authors: R Sharma, A George, M Nimmagadda, D Ortolan, BS Karla, Z Qureshy, D Bose, R Dejene, G Liang, Q Wan, J Chang, BS Jha, O Memon, KJ Miyagishim, A Rising, M Lal, E Hanson, R King, MM Campos, M Ferrer, J Amaral, D McGaughey, K Bharti
    Nature Communications, 2021;12(1):7293.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. TGFBR3L is an inhibin B co-receptor that regulates female fertility
    Authors: E Brûlé, Y Wang, Y Li, YF Lin, X Zhou, L Ongaro, CAI Alonso, ERS Buddle, AL Schneyer, CH Byeon, CS Hinck, N Mendelev, JP Russell, M Cowan, U Boehm, F Ruf-Zamojs, M Zamojski, CL Andoniadou, SC Sealfon, CA Harrison, KL Walton, AP Hinck, DJ Bernard
    Science Advances, 2021;7(51):eabl4391.
    Species: Hamster
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation
    Authors: M Grosch, S Ittermann, E Rusha, T Greisle, C Ori, DJ Truong, AC O'Neill, A Pertek, GG Westmeyer, M Drukker
    BMC Biol., 2020;18(1):42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  48. LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development
    Authors: NK Vinckier, NA Patel, RJ Geusz, A Wang, J Wang, I Matta, AR Harrington, M Wortham, N Wetton, J Wang, US Jhala, MG Rosenfeld, CW Benner, HP Shih, M Sander
    Nat Commun, 2020;11(1):2082.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells
    Authors: A Plaza Reye, S Petrus-Reu, S Padrell Sá, P Kumar, I Douagi, H Bartuma, M Aronsson, S Westman, E Lardner, H André, A Falk, EF Nandrot, A Kvanta, F Lanner
    Nat Commun, 2020;11(1):1609.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  50. A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem Cells
    Authors: H Tsujimoto, T Kasahara, SI Sueta, T Araoka, S Sakamoto, C Okada, SI Mae, T Nakajima, N Okamoto, D Taura, M Nasu, T Shimizu, M Ryosaka, Z Li, M Sone, M Ikeya, A Watanabe, K Osafune
    Cell Rep, 2020;31(1):107476.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Modeling Type 1 Diabetes In�Vitro Using Human Pluripotent Stem Cells
    Authors: NC Leite, E Sintov, TB Meissner, MA Brehm, DL Greiner, DM Harlan, DA Melton
    Cell Rep, 2020;32(2):107894.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  52. The translational landscape of ground state pluripotency
    Authors: Y Atlasi, SM Jafarnejad, CG Gkogkas, M Vermeulen, N Sonenberg, HG Stunnenber
    Nat Commun, 2020;11(1):1617.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Targeting all transforming growth factor-&beta isoforms with a Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer
    Authors: K Takahashi, Y Akatsu, KA Podyma-Ino, T Matsumoto, H Takahashi, Y Yoshimatsu, D Koinuma, M Shirouzu, K Miyazono, T Watabe
    J. Biol. Chem., 2020;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  54. Programmed Cell Death-1: Programmed Cell Death-Ligand 1 Interaction Protects Human Cardiomyocytes Against T-Cell Mediated Inflammation and Apoptosis Response In Vitro
    Authors: WT Tay, YH Fang, ST Beh, YW Liu, LW Hsu, CJ Yen, PY Liu
    Int J Mol Sci, 2020;21(7):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Expansion of Human iPSC-Derived Ureteric Bud Organoids with Repeated Branching Potential
    Authors: SI Mae, M Ryosaka, S Sakamoto, K Matsuse, A Nozaki, M Igami, R Kabai, A Watanabe, K Osafune
    Cell Rep, 2020;32(4):107963.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Comparison of commercially available media for hepatic differentiation and hepatocyte maintenance
    Authors: Y Toba, S Deguchi, N Mimura, A Sakamoto, K Harada, K Hirata, K Takayama, H Mizuguchi
    PLoS ONE, 2020;15(2):e0229654.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  57. The Transcription Factor OVOL2 Represses ID2 and Drives Differentiation of Trophoblast Stem Cells and Placental Development in Mice
    Authors: MJ Jeyarajah, G Jaju Bhatt, DM Hillier, SJ Renaud
    Cells, 2020;9(4):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Increased stiffness of the tumor microenvironment in colon cancer stimulates cancer associated fibroblast-mediated prometastatic activin A signaling
    Authors: J Bauer, MAB Emon, JJ Staudacher, AL Thomas, J Zessner-Sp, G Mancinelli, N Krett, MT Saif, B Jung
    Sci Rep, 2020;10(1):50.
    Species: Human
    Sample Types: cell culture
    Applications: Cell Culture
  59. Generation of intestinal organoids derived from human pluripotent stem cells for drug testing
    Authors: S Yoshida, H Miwa, T Kawachi, S Kume, K Takahashi
    Sci Rep, 2020;10(1):5989.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells
    Authors: M Nafria, P Keane, ES Ng, EG Stanley, AG Elefanty, C Bonifer
    Cell Rep, 2020;31(8):107691.
    Species: Human
    Sample Types:
    Applications: Bioassay
  61. Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells
    Authors: K Takeishi, A Collin de, Y Wang, K Handa, J Guzman-Lep, K Matsubara, K Morita, S Jang, N Haep, RM Florentino, F Yuan, K Fukumitsu, K Tobita, W Sun, J Franks, ER Delgado, EM Shapiro, NA Fraunhoffe, AW Duncan, H Yagi, T Mashimo, IJ Fox, A Soto-Gutie
    Cell Rep, 2020;31(9):107711.
    Species: Human
    Sample Types: cell culture
  62. BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
    Authors: LSW Loo, AAP Soetedjo, HH Lau, NHJ Ng, S Ghosh, L Nguyen, VG Krishnan, H Choi, X Roca, S Hoon, AKK Teo
    Cell Death Dis, 2020;11(5):378.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  63. iPSC-Derived Intestinal Organoids from Cystic Fibrosis Patients Acquire CFTR Activity upon TALEN-Mediated Repair of the p.F508del Mutation
    Authors: A Fleischer, S Vallejo-Dí, JM Martín-Fer, A Sánchez-Gi, M Castresana, A Del Pozo, A Esquisabel, S Ávila, JL Castrillo, E Gaínza, JL Pedraz, M Viñas, D Bachiller
    Mol Ther Methods Clin Dev, 2020;17(0):858-870.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  64. Establishment of SLC15A1/PEPT1-Knockout Human-Induced Pluripotent Stem Cell Line for Intestinal Drug Absorption Studies
    Authors: K Kawai, R Negoro, M Ichikawa, T Yamashita, S Deguchi, K Harada, K Hirata, K Takayama, H Mizuguchi
    Mol Ther Methods Clin Dev, 2020;17(0):49-57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  65. Sonic Hedgehog upregulation does not enhance the survival and engraftment of stem cell-derived cardiomyocytes in infarcted hearts
    Authors: JJ Weyers, JJ Gunaje, B Van Biber, A Martinson, H Reinecke, WM Mahoney, SM Schwartz, TC Cox, CE Murry
    PLoS ONE, 2020;15(1):e0227780.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  66. Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids
    Authors: A Motazedian, FF Bruveris, SV Kumar, JV Schiesser, T Chen, ES Ng, AP Chidgey, CA Wells, AG Elefanty, EG Stanley
    Nat. Cell Biol., 2020;22(1):60-73.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Cell Culture
  67. Activin A Modulates Inflammation in Acute Pancreatitis and Strongly Predicts Severe Disease Independent of Body Mass Index
    Authors: AL Thomas, K Castellano, G Mancinelli, Y Xia, J Bauer, C Yazici, G Fantuzzi, RF Hwang, NL Krett, GI Papachrist, DC Whitcomb, B Jung
    Clin Transl Gastroenterol, 2020;11(5):e00152.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  68. Involvement of activin signal pathway in cyclic apoptosis of the oviductal isthmic epithelium in cows
    Authors: Y Yamamoto, S Ito, K Okuda, K Kimura
    Theriogenology, 2020;153(0):143-150.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Cell Culture
  69. A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation
    Authors: N Chanthra, T Abe, M Miyamoto, K Sekiguchi, C Kwon, Y Hanazono, H Uosaki
    Sci Rep, 2020;10(1):4249.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Vascularized cardiac tissue construction with orientation by layer-by-layer method and 3D printer
    Authors: Y Tsukamoto, T Akagi, M Akashi
    Sci Rep, 2020;10(1):5484.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  71. TATA box-binding protein-related factor 3 drives the mesendoderm specification of human embryonic stem cells by globally interacting with the TATA box of key mesendodermal genes
    Authors: H Liang, P Zhang, HJ Bai, J Huang, HT Yang
    Stem Cell Res Ther, 2020;11(1):196.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  72. Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells
    Authors: NJ Hogrebe, P Augsornwor, KG Maxwell, L Velazco-Cr, JR Millman
    Nat. Biotechnol., 2020;0(0):.
    Species: Human
    Sample Types: Cells
    Applications: Cell Culture
  73. Machine learning identifies abnormal Ca2+ transients in human induced pluripotent stem cell-derived cardiomyocytes
    Authors: H Hwang, R Liu, JT Maxwell, J Yang, C Xu
    Sci Rep, 2020;10(1):16977.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation
    Authors: LTP Khoa, YC Tsan, F Mao, DM Kremer, P Sajjakulnu, L Zhang, B Zhou, X Tong, NV Bhanu, C Choudhary, BA Garcia, L Yin, GD Smith, TL Saunders, SL Bielas, CA Lyssiotis, Y Dou
    Cell Stem Cell, 2020;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development
    Authors: M Yagi, M Kabata, A Tanaka, T Ukai, S Ohta, K Nakabayash, M Shimizu, K Hata, A Meissner, T Yamamoto, Y Yamada
    Nat Commun, 2020;11(1):3199.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  76. HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells
    Authors: Y Wang, L Lifshitz, K Gellatly, CL Vinton, K Busman-Sah, S McCauley, P Vangala, K Kim, A Derr, S Jaiswal, A Kucukural, P McDonel, PW Hunt, T Greenough, J Houghton, M Somsouk, JD Estes, JM Brenchley, M Garber, SG Deeks, J Luban
    Nat. Immunol., 2020;21(3):274-286.
    Species: Human
    Sample Types: Cells
  77. Human Pluripotent Stem Cell-Derived Kidney Organoids with Improved Collecting Duct Maturation and Injury Modeling
    Authors: K Uchimura, H Wu, Y Yoshimura, BD Humphreys
    Cell Reports, 2020;33(11):108514.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  78. The Microfluidic Environment Reveals a Hidden Role of Self-Organizing Extracellular Matrix in Hepatic Commitment and Organoid Formation of hiPSCs
    Authors: F Michielin, GG Giobbe, C Luni, Q Hu, I Maroni, MR Orford, A Manfredi, L Di Filippo, AL David, D Cacchiarel, P De Coppi, S Eaton, N Elvassore
    Cell Rep, 2020;33(9):108453.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State
    Authors: L Zhang, J Avery, A Yin, AM Singh, TS Cliff, H Yin, S Dalton
    Cell Stem Cell, 2020;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development
    Authors: EI Crosse, S Gordon-Key, S Rybtsov, A Binagui-Ca, H Felchle, NC Nnadi, K Kirschner, T Chandra, S Tamagno, DJ Webb, F Rossi, RA Anderson, A Medvinsky
    Cell Stem Cell, 2020;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Exosome-Mediated Differentiation of Mouse Embryonic Fibroblasts and Exocrine Cells into &beta-Like Cells and the Identification of Key miRNAs for Differentiation
    Authors: P Mandal, D De, DU Im, SH Um, KK Kim
    Biomedicines, 2020;8(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  82. Duchenne muscular dystrophy (DMD) cardiomyocyte-secreted exosomes promote the pathogenesis of DMD-associated cardiomyopathy
    Authors: M Gartz, CW Lin, MA Sussman, MW Lawlor, JL Strande
    Dis Model Mech, 2020;13(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  83. Antagonistic effects of activin A and TNF-&alpha on the activation of L929 fibroblast cells via Smad3-independent signaling
    Authors: L Jiang, B Liu, Y Qi, L Zhu, X Cui, Z Liu
    Sci Rep, 2020;10(1):20623.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  84. Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells
    Authors: YS Hwang, S Suzuki, Y Seita, J Ito, Y Sakata, H Aso, K Sato, BP Hermann, K Sasaki
    Nat Commun, 2020;11(1):5656.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  85. TMEPAI/PMEPA1 Is a Positive Regulator of Skeletal Muscle Mass
    Authors: A Hagg, S Kharoud, G Goodchild, CA Goodman, JL Chen, RE Thomson, H Qian, P Gregorevic, CA Harrison, KL Walton
    Front Physiol, 2020;11(0):560225.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Drug-Induced Na�ve iPS Cells Exhibit Better Performance than Primed iPS Cells with Respect to the Ability to Differentiate into Pancreatic &beta-Cell Lineage
    Authors: Y Kiyokawa, M Sato, H Noguchi, E Inada, Y Iwase, N Kubota, T Sawami, M Terunuma, T Maeda, H Hayasaki, I Saitoh
    Journal of Clinical Medicine, 2020;9(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
    Authors: RM Samuel, H Majd, MN Richter, Z Ghazizadeh, SM Zekavat, A Navickas, JT Ramirez, H Asgharian, CR Simoneau, LR Bonser, KD Koh, M Garcia-Kni, M Tassetto, S Sunshine, S Farahvashi, A Kalantari, W Liu, R Andino, H Zhao, P Natarajan, DJ Erle, M Ott, H Goodarzi, F Fattahi
    Cell Stem Cell, 2020;27(6):876-889.e12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Generation of a human induced pluripotent stem cell line (iPSC) from peripheral blood mononuclear cells of a patient with a myasthenic syndrome due to mutation in COLQ
    Authors: S Barbeau, R Desprat, B Eymard, C Martinat, JM Lemaitre, C Legay
    Stem Cell Research, 2020;49(0):102106.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Rapid generation of regionally specified CNS neurons by sequential patterning and conversion of human induced pluripotent stem cells
    Authors: M Chen, M Maimaitili, M Habekost, KP Gill, N Mermet-Jor, S Nabavi, F Febbraro, M Denham
    Stem Cell Res, 2020;48(0):101945.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  90. In vitro testicular organogenesis from human fetal gonads produces fertilization-competent spermatids
    Authors: Y Yuan, L Li, Q Cheng, F Diao, Q Zeng, X Yang, Y Wu, H Zhang, M Huang, J Chen, Q Zhou, Y Zhu, R Hua, J Tian, X Wang, Z Zhou, J Hao, J Yu, D Hua, J Liu, X Guo, Q Zhou, J Sha
    Cell Res., 2020;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  91. Nucleoside Diphosphate Kinase B Contributes to Arrhythmogenesis in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Arrhythmogenic Right Ventricular Cardiomyopathy
    Authors: F Buljubasic, I El-Battraw, H Lan, SK Lomada, A Chatterjee, Z Zhao, X Li, R Zhong, Q Xu, M Huang, Z Liao, S Lang, L Cyganek, X Zhou, T Wieland, M Borggrefe, I Akin
    J Clin Med, 2020;9(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  92. Specific induction and long-term maintenance of high purity ventricular cardiomyocytes from human induced pluripotent stem cells
    Authors: H Fukushima, M Yoshioka, M Kawatou, V López-Dávi, M Takeda, Y Kanda, Y Sekino, Y Yoshida, JK Yamashita
    PLoS ONE, 2020;15(11):e0241287.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. ER stress reliever enhances functionalities of in vitro cultured hepatocytes
    Authors: JS Kim, SI Hwang, JL Ryu, HS Hong, JM Lee, SM Lee, X Jin, C Han, JH Kim, J Han, MR Lee, DH Woo
    Stem Cell Res, 2020;43(0):101732.
    Species: Human
    Sample Types: cell culture
    Applications: Bioassay
  94. A paracrine activin A-mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming
    Authors: M Cangkrama, M Wietecha, N Mathis, R Okumura, L Ferrarese, D Al-Nuaimi, M Antsiferov, R Dummer, M Innocenti, S Werner
    EMBO Mol Med, 2020;0(0):e11466.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  95. A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets
    Authors: M Liu, Q Yan, Y Sun, Y Nam, L Hu, JH Loong, Q Ouyang, Y Zhang, HL Li, FE Kong, L Li, Y Li, MM Li, W Cheng, LX Jiang, S Fang, XD Yang, JQ Mo, YF Gong, YQ Tang, Y Li, YF Yuan, NF Ma, G Lin, S Ma, JG Wang, XY Guan
    Proc. Natl. Acad. Sci. U.S.A., 2020;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  96. An in vitro model for studying CNS white matter: functional properties and experimental approaches
    Authors: S Bijland, G Thomson, M Euston, K Michail, K Thümmler, S Mücklisch, CL Crawford, SC Barnett, M McLaughlin, TJ Anderson, C Linington, ER Brown, ER Kalkman, JM Edgar
    F1000Res, 2019;8(0):117.
    Species: Mouse
    Sample Types: Embryonic Spinal Cord Cells
    Applications: Bioassay
  97. User-defined morphogen patterning for directing human cell fate stratification
    Authors: MC Regier, JJ Tokar, JW Warrick, L Pabon, E Berthier, DJ Beebe, KR Stevens
    Sci Rep, 2019;9(1):6433.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Delivery of pancreatic digestive enzymes into the gastrointestinal tract by pancreatic exocrine tissue transplant
    Authors: K Ito, K Matsuura, Y Mihara, Y Sakamoto, K Hasegawa, N Kokudo, T Shimizu
    Sci Rep, 2019;9(1):5922.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
    Authors: RMJ Genga, EM Kernfeld, KM Parsi, TJ Parsons, MJ Ziller, R Maehr
    Cell Rep, 2019;27(3):708-718.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  100. YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing ? cells
    Authors: EA Rosado-Oli, K Anderson, JH Kenty, DA Melton
    Nat Commun, 2019;10(1):1464.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Cell cycle dynamics of human pluripotent stem cells primed for differentiation
    Authors: A Shcherbina, J Li, C Narayanan, W Greenleaf, A Kundaje, S Chetty
    Stem Cells, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  102. Novel hybrid three-dimensional artificial liver using human induced pluripotent stem cells and a rat decellularized liver scaffold
    Authors: T Minami, T Ishii, K Yasuchika, K Fukumitsu, S Ogiso, Y Miyauchi, H Kojima, T Kawai, R Yamaoka, Y Oshima, H Kawamoto, M Kotaka, K Yasuda, K Osafune, S Uemoto
    Regen Ther, 2019;10(0):127-133.
    Species: Human
    Sample Types: Liver hiPSCs
    Applications: Cell Culture
  103. A GDF11/myostatin inhibitor, GDF11 propeptide-Fc, increases skeletal muscle mass and improves muscle strength in dystrophic mdx mice
    Authors: Q Jin, C Qiao, J Li, B Xiao, J Li, X Xiao
    Skelet Muscle, 2019;9(1):16.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Bioassay
  104. Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development
    Authors: N Sharon, J Vanderhoof, J Straubhaar, J Mueller, R Chawla, Q Zhou, EN Engquist, C Trapnell, DK Gifford, DA Melton
    Cell Rep, 2019;27(8):2281-2291.e5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
    Authors: B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat
    Cell Rep, 2019;27(2):599-615.e12.
    Species: Human
    Sample Types: cell culture
    Applications: Differentiation
  106. An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos
    Authors: L Liu, L Leng, C Liu, C Lu, Y Yuan, L Wu, F Gong, S Zhang, X Wei, M Wang, L Zhao, L Hu, J Wang, H Yang, S Zhu, F Chen, G Lu, Z Shang, G Lin
    Nat Commun, 2019;10(1):364.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. Identification of the minimum region of flatfish myostatin propeptide (Pep45-65) for myostatin inhibition and its potential to enhance muscle growth and performance in animals
    Authors: JH Kim, JH Kim, LA Sutikno, SB Lee, DH Jin, YK Hong, YS Kim, HJ Jin
    PLoS ONE, 2019;14(4):e0215298.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Establishing Liposome-Immobilized Dexamethasone-Releasing PDMS Membrane for the Cultivation of Retinal Pigment Epithelial Cells and Suppression of Neovascularization
    Authors: TW Lin, Y Chien, YY Lin, ML Wang, AA Yarmishyn, YP Yang, DK Hwang, CH Peng, CC Hsu, SJ Chen, KH Chien
    Int J Mol Sci, 2019;20(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Generation of lung organoids from human pluripotent stem cells in vitro
    Authors: AJ Miller, BR Dye, D Ferrer-Tor, DR Hill, AW Overeem, LD Shea, JR Spence
    Nat Protoc, 2019;14(2):518-540.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells
    Authors: A Montel-Hag, CS Seet, S Li, B Chick, Y Zhu, P Chang, S Tsai, V Sun, S Lopez, HC Chen, C He, CJ Chin, D Casero, GM Crooks
    Cell Stem Cell, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair
    Authors: T Colunga, M Hayworth, S Kre beta, DM Reynolds, L Chen, KL Nazor, J Baur, AM Singh, JF Loring, M Metzger, S Dalton
    Cell Rep, 2019;26(10):2566-2579.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
    Authors: H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta
    Cell Stem Cell, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Point mutations in the PDX1 transactivation domain impair human ?-cell development and function
    Authors: X Wang, M Sterr, Ansarullah, I Burtscher, A Böttcher, J Beckenbaue, J Siehler, T Meitinger, HU Häring, H Staiger, FM Cernilogar, G Schotta, M Irmler, J Beckers, CVE Wright, M Bakhti, H Lickert
    Mol Metab, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Differentiation
  114. FGF signal is not required for hepatoblast differentiation of human iPS cells
    Authors: Y Toba, A Kiso, S Nakamae, F Sakurai, K Takayama, H Mizuguchi
    Sci Rep, 2019;9(1):3713.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  115. Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application
    Authors: E Ito, S Miyagawa, M Takeda, A Kawamura, A Harada, H Iseoka, S Yajima, N Sougawa, N Mochizuki-, S Yasuda, Y Sato, Y Sawa
    Sci Rep, 2019;9(1):1881.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Cell population balance of cardiovascular spheroids derived from human induced pluripotent stem cells
    Authors: Y Yan, J Bejoy, J Xia, K Griffin, J Guan, Y Li
    Sci Rep, 2019;9(1):1295.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  117. Differentiation and isolation of iPSC-derived remodeling ductal plate-like cells by use of an AQP1-GFP reporter human iPSC line
    Authors: S Matsui, M Ochiai, K Yasuda, SI Mae, M Kotaka, T Toyoda, T Yamamoto, K Osafune
    Stem Cell Res, 2019;35(0):101400.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Induction of Expandable Tissue-Specific Progenitor Cells from Human Pancreatic Tissue through Transient Expression of Defined Factors
    Authors: H Noguchi, C Miyagi-Shi, Y Nakashima, T Kinjo, N Kobayashi, I Saitoh, M Watanabe, AMJ Shapiro, T Kin
    Mol Ther Methods Clin Dev, 2019;13(0):243-252.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Time dependent degeneration of the nigrostriatal tract in mice with 6-OHDA lesioned medial forebrain bundle and the effect of activin A on L-Dopa induced dyskinesia
    Authors: P Rentsch, S Stayte, GP Morris, B Vissel
    BMC Neurosci, 2019;20(1):5.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  120. Excess growth hormone suppresses DNA damage repair in epithelial cells
    Authors: V Chesnokova, S Zonis, R Barrett, H Kameda, K Wawrowsky, A Ben-Shlomo, M Yamamoto, J Gleeson, C Bresee, V Gorbunova, S Melmed
    JCI Insight, 2019;4(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  121. Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency
    Authors: Y Atlasi, W Megchelenb, T Peng, E Habibi, O Joshi, SY Wang, C Wang, C Logie, I Poser, H Marks, HG Stunnenber
    Nat. Cell Biol., 2019;21(5):568-578.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation
  122. Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells
    Authors: C Song, F Xu, Z Ren, Y Zhang, Y Meng, Y Yang, S Lingadahal, E Cheung, G Li, W Liu, J Wan, Y Zhao, G Chen
    Stem Cell Reports, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  123. Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals
    Authors: T Yung, F Poon, M Liang, S Coquenlorg, EC McGaugh, CC Hui, MD Wilson, MC Nostro, TH Kim
    Nat Commun, 2019;10(1):4647.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2
    Authors: FM Cernilogar, S Hasenöder, Z Wang, K Scheibner, I Burtscher, M Sterr, P Smialowski, S Groh, IM Evenroed, GD Gilfillan, H Lickert, G Schotta
    Nucleic Acids Res., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  125. Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells
    Authors: W Liang, P Han, EH Kim, J Mak, R Zhang, AG Torrente, JI Goldhaber, E Marbán, HC Cho
    Stem Cells, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Involvement of CHOP in activin A?induced myeloma NS?1 cell apoptosis
    Authors: J Ge, H Sun, J Li, Y Shan, Y Zhao, F Liao, Y Yang, X Cui, Z Liu
    Oncol. Rep., 2019;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  127. Adequate taylor couette flow-mediated shear stress is useful for dissociating human iPS cell-derived cell aggregates
    Authors: K Matsuura, M Wada, K Sakaguchi, Y Matsuhashi, T Shimizu
    Regen Ther, 2019;12(0):6-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Endodermal differentiation of human induced pluripotent stem cells using simple dialysis culture system in suspension culture
    Authors: M Shinohara, H Choi, M Ibuki, SG Yabe, H Okochi, A Miyajima, Y Sakai
    Regen Ther, 2019;12(0):14-19.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Controlled modelling of human epiblast and amnion development using stem cells
    Authors: Y Zheng, X Xue, Y Shao, S Wang, SN Esfahani, Z Li, JM Muncie, JN Lakins, VM Weaver, DL Gumucio, J Fu
    Nature, 2019;573(7774):421-425.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Synergistic modulation of signaling pathways to expand and maintain the bipotency of human hepatoblasts
    Authors: T Pan, Y Chen, Y Zhuang, F Yang, Y Xu, J Tao, K You, N Wang, Y Wu, X Lin, F Wu, Y Liu, Y Li, G Wang, YX Li
    Stem Cell Res Ther, 2019;10(1):364.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells
    Authors: KB Jung, O Kwon, MO Lee, H Lee, YS Son, O Habib, JH Oh, HS Cho, CR Jung, J Kim, MY Son
    J Clin Med, 2019;8(7):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Manipulating energy migration within single lanthanide activator for switchable upconversion emissions towards bidirectional photoactivation
    Authors: Q Mei, A Bansal, MKG Jayakumar, Z Zhang, J Zhang, H Huang, D Yu, CJA Ramachandr, DJ Hausenloy, TW Soong, Y Zhang
    Nat Commun, 2019;10(1):4416.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals
    Authors: GE Gentsch, T Spruce, NDL Owens, JC Smith
    Nat Commun, 2019;10(1):4269.
    Species: Xenopus
    Sample Types: Tissue Explant
    Applications: Bioassay
  134. H3K18ac Primes Mesendodermal Differentiation upon Nodal Signaling
    Authors: M Luo, J Bai, B Liu, P Yan, F Zuo, H Sun, Y Sun, X Xu, Z Song, Y Yang, J Massagué, X Lan, Z Lu, YG Chen, H Deng, W Xie, Q Xi
    Stem Cell Reports, 2019;13(4):642-656.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  135. A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
    Authors: M Prajapati-, A Benito-Gon, EJ Golden, S Zhang, A Doetzlhofe
    Elife, 2019;8(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  136. Engineering transferrable microvascular meshes for subcutaneous islet transplantation
    Authors: W Song, A Chiu, LH Wang, RE Schwartz, B Li, N Bouklas, DT Bowers, D An, SH Cheong, JA Flanders, Y Pardo, Q Liu, X Wang, VK Lee, G Dai, M Ma
    Nat Commun, 2019;10(1):4602.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  137. SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells through Mediating the Transcriptional Activation of Key Mesendodermal Genes
    Authors: HJ Bai, P Zhang, L Ma, H Liang, G Wei, HT Yang
    Stem Cells, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model
    Authors: S Pecha, K Yorgan, M Röhl, B Geertz, A Hansen, F Weinberger, S Sehner, H Ehmke, H Reichenspu, T Eschenhage, AP Schwoerer
    Sci Rep, 2019;9(1):9831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  139. Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells
    Authors: KB Jung, O Kwon, MO Lee, H Lee, YS Son, O Habib, JH Oh, HS Cho, CR Jung, J Kim, MY Son
    J Clin Med, 2019;8(7):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Generation of eight human induced pluripotent stem cell lines from Parkinson's disease patients carrying familial mutations
    Authors: M Chen, M Maimaitili, SH Buchholdt, UB Jensen, F Febbraro, M Denham
    Stem Cell Res, 2019;42(0):101657.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  141. Dynamic proteome profiling of human pluripotent stem cell-derived pancreatic progenitors
    Authors: LSW Loo, H Vethe, AAP Soetedjo, JA Paulo, J Jasmen, N Jackson, Y Bjørlykke, IA Valdez, M Vaudel, H Barsnes, SP Gygi, H Raeder, AKK Teo, RN Kulkarni
    Stem Cells, 2019;0(0):.
    Species: Human
    Sample Types:
    Applications: Bioassay
  142. BMPR2 acts as a�gatekeeper to protect endothelial cells from increased TGF&beta�responses and altered cell mechanics
    Authors: C Hiepen, J Jatzlau, S Hildebrand, B Kampfrath, M Goktas, A Murgai, JL Cuellar Ca, R Haag, C Ruppert, G Sengle, EA Cavalcanti, KG Blank, P Knaus
    PLoS Biol., 2019;17(12):e3000557.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Exploring the Molecular Crosstalk between Pancreatic Bud and Mesenchyme in Embryogenesis: Novel Signals Involved
    Authors: I Guerriero, MT De Angelis, F D'Angelo, R Leveque, E Savignano, L Roberto, V Lucci, P Mazzone, S Laurino, G Storto, A Nardelli, A Sgambato, M Ceccarelli, M De Felice, E Amendola, G Falco
    Int J Mol Sci, 2019;20(19):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  144. Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation
    Authors: A Subramania, EH Sidhom, M Emani, K Vernon, N Sahakian, Y Zhou, M Kost-Alimo, M Slyper, J Waldman, D Dionne, LT Nguyen, A Weins, JL Marshall, O Rosenblatt, A Regev, A Greka
    Nat Commun, 2019;10(1):5462.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  145. Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva
    Authors: JB Lees-Shepa, M Yamamoto, AA Biswas, SJ Stoessel, SE Nicholas, CA Cogswell, PM Devarakond, MJ Schneider, SM Cummins, NP Legendre, S Yamamoto, V Kaartinen, JW Hunter, DJ Goldhamer
    Nat Commun, 2018;9(1):471.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  146. A transient DMSO treatment increases the differentiation potential of human pluripotent stem cells through the Rb family
    Authors: J Li, C Narayanan, J Bian, D Sambo, T Brickler, W Zhang, S Chetty
    PLoS ONE, 2018;13(12):e0208110.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  147. Development of a Graphene Oxide-Incorporated Polydimethylsiloxane Membrane with Hexagonal Micropillars
    Authors: YY Lin, Y Chien, JH Chuang, CC Chang, YP Yang, YH Lai, WL Lo, KH Chien, TI Huo, CY Wang
    Int J Mol Sci, 2018;19(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Analyzing bovine OCT4 and NANOG enhancer activity in pluripotent stem cells using fluorescent protein reporters
    Authors: D Huang, L Wang, NC Talbot, C Huang, L Pu, X Zhao, X Tian, M Zhang, Y Tang
    PLoS ONE, 2018;13(10):e0203923.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Preparation of iPS cell-derived CD31+ endothelial cells using three-dimensional suspension culture
    Authors: S Masuda, K Matsuura, T Shimizu
    Regen Ther, 2018;9(0):1-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  150. Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors
    Authors: H Ida, T Akiyama, K Ishiguro, SK Goparaju, Y Nakatake, N Chikazawa-, S Sato, H Kimura, Y Yokoyama, M Nagino, MSH Ko, SBH Ko
    Stem Cell Res Ther, 2018;9(1):277.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  151. 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
    Authors: Y Zhang, Y Yang, M Jiang, SX Huang, W Zhang, D Al Alam, S Danopoulos, M Mori, YW Chen, R Balasubram, SM Chuva de S, C Serra, M Bialecka, E Kim, S Lin, ALR Toste de C, PN Riccio, WV Cardoso, X Zhang, HW Snoeck, J Que
    Cell Stem Cell, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Tributyltin Inhibits Neural Induction of Human Induced Pluripotent Stem Cells
    Authors: S Yamada, Y Kubo, D Yamazaki, Y Sekino, Y Nomura, S Yoshida, Y Kanda
    Sci Rep, 2018;8(1):12155.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Functional 3D Human Liver Bud Assembled from MSC-Derived Multiple Liver Cell Lineages
    Authors: J Li, F Xing, F Chen, L He, KF So, Y Liu, J Xiao
    Cell Transplant, 2018;0(0):9636897187803.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Klf5 suppresses ERK signaling in mouse pluripotent stem cells
    Authors: T Azami, K Matsumoto, H Jeon, T Waku, M Muratani, H Niwa, S Takahashi, M Ema
    PLoS ONE, 2018;13(11):e0207321.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery
    Authors: Y Jin, Y Liu, Z Li, K Santostefa, J Shi, X Zhang, D Wu, Z Cheng, W Wu, N Terada, S Jin, F Bai
    PLoS ONE, 2018;13(3):e0194895.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Precardiac organoids form two heart fields via Bmp/Wnt signaling
    Authors: P Andersen, E Tampakakis, DV Jimenez, S Kannan, M Miyamoto, HK Shin, A Saberi, S Murphy, E Sulistio, SP Chelko, C Kwon
    Nat Commun, 2018;9(1):3140.
    Species: Mouse
    Sample Types: Spheroids
    Applications: Bioassay
  157. Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis
    Authors: MA Scavuzzo, MC Hill, J Chmielowie, D Yang, J Teaw, K Sheng, Y Kong, M Bettini, C Zong, JF Martin, M Borowiak
    Nat Commun, 2018;9(1):3356.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Different murine-derived feeder cells alter the definitive endoderm differentiation of human induced pluripotent stem cells
    Authors: M Shoji, H Minato, S Ogaki, M Seki, Y Suzuki, S Kume, T Kuzuhara
    PLoS ONE, 2018;13(7):e0201239.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Characterization of induced tissue-specific stem cells from pancreas by a synthetic self-replicative RNA
    Authors: C Miyagi-Shi, Y Nakashima, N Kobayashi, I Saitoh, M Watanabe, H Noguchi
    Sci Rep, 2018;8(1):12341.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Cardiomyocytes Derived from Human CardiopoieticAmniotic Fluids
    Authors: A Di Baldass, MA D'Amico, P Izzicupo, G Gaggi, S Guarnieri, MA Mariggiò, I Antonucci, B Corneo, D Sirabella, L Stuppia, B Ghinassi
    Sci Rep, 2018;8(1):12028.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Analysis of differentially expressed genes among human hair follicle-derived iPSCs, induced hepatocyte-like cells, and primary hepatocytes
    Authors: Z Xu, X He, X Shi, Y Xia, X Liu, H Wu, P Li, H Zhang, W Yin, X Du, L Li, Y Li
    Stem Cell Res Ther, 2018;9(1):211.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA
    Authors: MA Scavuzzo, J Chmielowie, D Yang, K Wamble, LS Chaboub, L Duraine, B Tepe, SM Glasgow, BR Arenkiel, C Brou, B Deneen, M Borowiak
    Cell Rep, 2018;25(13):3811-3827.e7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  163. Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice
    Authors: YY Sin, LL Ballantyne, CR Richmond, CD Funk
    Mol Ther Nucleic Acids, 2018;10(0):122-130.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  164. The plant alkaloid conophylline inhibits matrix formation of fibroblasts
    Authors: T Tezuka, A Ota, S Karnan, K Matsuura, K Yokoo, Y Hosokawa, D Vigetti, A Passi, S Hatano, K Umezawa, H Watanabe
    J. Biol. Chem., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Stimulation
  165. The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin
    Authors: L Galvan, L Francelle, MC Gaillard, L de Longpre, MA Carrillo-d, G Liot, K Cambon, L Stimmer, S Luccantoni, J Flament, J Valette, M de Chaldée, G Auregan, M Guillermie, C Joséphine, F Petit, C Jan, M Jarrige, N Dufour, G Bonvento, S Humbert, F Saudou, P Hantraye, K Merienne, AP Bemelmans, AL Perrier, N Déglon, E Brouillet
    Brain, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
    Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
    Sci Rep, 2018;8(1):1561.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  167. Functional comparison of distinct Brachyury+ states in a renal differentiation assay
    Authors: J Zhou, A Plagge, P Murray
    Biol Open, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions
    Authors: A Yachie-Kin, K Onishi, J Ostblom, MA Langley, E Posfai, J Rossant, PW Zandstra
    Mol. Syst. Biol., 2018;14(1):e7952.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  169. TGF? signaling hyperactivation-induced tumorigenicity during the derivation of neural progenitors from mouse ESCs
    Authors: X Yang, R Wang, X Wang, G Cai, Y Qian, S Feng, F Tan, K Chen, K Tang, X Huang, N Jing, Y Qiao
    J Mol Cell Biol, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Beta-Catenin maintains lung epithelial progenitors after lung specification
    Authors: EJ Ostrin, DR Little, KN Gerner-Mau, EA Sumner, R Ríos-Corzo, E Ambrosio, SE Holt, NR Forcioli-C, H Akiyama, SM Hanash, S Kimura, SXL Huang, J Chen
    Development, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Activin receptors regulate the oligodendrocyte lineage in health and disease
    Authors: A Dillenburg, G Ireland, RK Holloway, CL Davies, FL Evans, M Swire, ME Bechler, D Soong, TJ Yuen, GH Su, JC Becher, C Smith, A Williams, VE Miron
    Acta Neuropathol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs
    Authors: M Chen, SH Laursen, M Habekost, CH Knudsen, SH Buchholdt, J Huang, F Xu, X Liu, L Bolund, Y Luo, P Nissen, F Febbraro, M Denham
    Front Cell Dev Biol, 2018;6(0):5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  173. Billion-scale production of hepatocyte-like cells from human induced pluripotent stem cells
    Authors: T Yamashita, K Takayama, F Sakurai, H Mizuguchi
    Biochem. Biophys. Res. Commun., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Differentiation
  174. Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies
    Authors: R Negoro, K Takayama, K Kawai, K Harada, F Sakurai, K Hirata, H Mizuguchi
    Stem Cell Reports, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  175. Reactivation of the Nkx2.5 cardiac enhancer after myocardial infarction does not presage myogenesis
    Authors: MA Deutsch, SA Doppler, X Li, H Lahm, G Santamaria, G Cuda, S Eichhorn, T Ratschille, E Dzilic, M Dre beta en, A Eckart, K Stark, S Massberg, A Bartels, C Rischpler, R Gilsbach, L Hein, BK Fleischman, SM Wu, R Lange, M Krane
    Cardiovasc. Res., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  176. In vitro platform of allogeneic stem cell-derived cardiomyocyte transplantation for cardiac conduction defects
    Authors: A Yoshida, JK Lee, S Tomoyama, K Miwa, K Shirakawa, S Hamanaka, T Yamaguchi, H Nakauchi, S Miyagawa, Y Sawa, I Komuro, Y Sakata
    Europace, 2018;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  177. WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
    Authors: A Yoney, F Etoc, A Ruzo, T Carroll, JJ Metzger, I Martyn, S Li, C Kirst, ED Siggia, AH Brivanlou
    Elife, 2018;7(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.
    Authors: Michael J Workman, John P Gleeson, Elissa J Troisi, Hannah Q Estrada, S Jordan Kerns, Christopher D Hinojosa, Geraldine A Hamilton, Stephan R Targan, Clive N Svendsen, Robert J Barrett
    Cellular and Molecular Gastroenterology and Hepatology, 2018;0(0):2352-345X.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  179. A single cell transcriptional portrait of embryoid body differentiation and comparison to progenitors of the developing embryo
    Authors: A Spangler, EY Su, AM Craft, P Cahan
    Stem Cell Res, 2018;31(0):201-215.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Noncoding RNA Transcripts during Differentiation of Induced Pluripotent Stem Cells into Hepatocytes
    Authors: A Skrzypczyk, S Kehr, I Krystel, SH Bernhart, S Giri, A Bader, PF Stadler
    Stem Cells Int, 2018;2018(0):5692840.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics
    Authors: H Wu, K Uchimura, EL Donnelly, Y Kirita, SA Morris, BD Humphreys
    Cell Stem Cell, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis
    Authors: A Jørgensen, J Macdonald, JE Nielsen, KR Kilcoyne, S Perlman, L Lundvall, L Langhoff T, K Juul Hare, H Frederikse, AM Andersson, NE Skakkebæk, A Juul, RM Sharpe, E Rajpert-De, RT Mitchell
    Cell Rep, 2018;25(7):1924-1937.e4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem�Cells
    Authors: F Zambelli, J Mertens, D Dziedzicka, J Sterckx, C Markouli, A Keller, P Tropel, L Jung, S Viville, H Van de Vel, M Geens, S Seneca, K Sermon, C Spits
    Stem Cell Reports, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Effects of lung and airway epithelial maturation cocktail on the structure of lung bud organoids
    Authors: E Magro-Lope, C Palmer, J Manso, I Liste, A Zambrano
    Stem Cell Res Ther, 2018;9(1):186.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage
    Authors: RP Russell, Y Fu, Y Liu, P Maye
    Stem Cell Res, 2018;30(0):85-95.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Functional innate immunity restricts Hepatitis C Virus infection in induced pluripotent stem cell-derived hepatocytes
    Authors: A Schöbel, K Rösch, E Herker
    Sci Rep, 2018;8(1):3893.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing
    Authors: C Long, H Li, M Tiburcy, C Rodriguez-, V Kyrychenko, H Zhou, Y Zhang, YL Min, JM Shelton, PPA Mammen, NY Liaw, WH Zimmermann, R Bassel-Dub, JW Schneider, EN Olson
    Sci Adv, 2018;4(1):eaap9004.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC
    Authors: J Li, X Wu, Y Zhou, M Lee, L Guo, W Han, W Mo, WM Cao, D Sun, R Xie, Y Huang
    Nucleic Acids Res., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids
    Authors: RR Zhang, M Koido, T Tadokoro, R Ouchi, T Matsuno, Y Ueno, K Sekine, T Takebe, H Taniguchi
    Stem Cell Reports, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells
    Authors: J Tu, G Tian, HH Cheung, W Wei, TL Lee
    Stem Cell Res Ther, 2018;9(1):71.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  191. Identification of direct negative crosstalk between the SLIT2 and Bone Morphogenetic Protein-Gremlin signaling pathways
    Authors: KE Tumelty, N Higginson-, X Fan, P Bajaj, KM Knowlton, M Shamashkin, AJ Coyle, W Lu, SP Berasi
    J. Biol. Chem., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  192. Human iPS Cell-based Liver-like Tissue Engineering at Extrahepatic Sites in Mice as a New Cell Therapy for Hemophilia B
    Authors: R Okamoto, K Takayama, N Akita, Y Nagamoto, D Hosokawa, S Iizuka, F Sakurai, H Suemizu, K Ohashi, H Mizuguchi
    Cell Transplant, 2018;27(2):299-309.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips
    Authors: MJ Workman, JP Gleeson, EJ Troisi, HQ Estrada, SJ Kerns, CD Hinojosa, GA Hamilton, SR Targan, CN Svendsen, RJ Barrett
    Cell Mol Gastroenterol Hepatol, 2018;5(4):669-677.e2.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors
    Authors: X Wang, M Sterr, I Burtscher, S Chen, A Hieronimus, F Machicao, H Staiger, HU Häring, G Lederer, T Meitinger, FM Cernilogar, G Schotta, M Irmler, J Beckers, M Hrab? de A, M Ray, CVE Wright, M Bakhti, H Lickert
    Mol Metab, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  195. The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development
    Authors: K Koefoed, J Skat-Rørda, P Andersen, CB Warzecha, M Pye, TA Andersen, KD Ajbro, E Bendsen, M Narimatsu, F Vilhardt, LB Pedersen, JL Wrana, RH Anderson, K Møllgård, ST Christense, LA Larsen
    Sci Rep, 2018;8(1):9542.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  196. A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis
    Authors: X Guo, Y Xu, Z Wang, Y Wu, J Chen, G Wang, C Lu, W Jia, J Xi, S Zhu, Z Jiapaer, X Wan, Z Liu, S Gao, J Kang
    Cell Stem Cell, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Conserved miR-10 family represses proliferation and induces apoptosis in ovarian granulosa cells
    Authors: T Jiajie, Y Yanzhou, AC Hoi-Hung, C Zi-Jiang, C Wai-Yee
    Sci Rep, 2017;7(0):41304.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  198. Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo
    Authors: CS Simon, DJ Downes, ME Gosden, J Telenius, DR Higgs, JR Hughes, I Costello, EK Bikoff, EJ Robertson
    Development, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells
    Nat Protoc, 2017;12(1):195-207.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity
    Authors: Y Choudhury, YC Toh, J Xing, Y Qu, J Poh, L Huan, HS Tan, R Kanesvaran, H Yu, MH Tan
    Sci Rep, 2017;7(0):41238.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  201. BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-? receptor type I ALK5
    Authors: LK Bollum, K Huse, MP Oksvold, B Bai, VI Hilden, L Forfang, SO Yoon, S Wälchli, EB Smeland, JH Myklebust
    PLoS ONE, 2017;12(5):e0177188.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  202. Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells
    Nat Protoc, 2017;12(1):15-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Derivation of hypermethylated pluripotent embryonic stem cells with high potency
    Authors: S Bao, WW Tang, B Wu, S Kim, J Li, L Li, T Kobayashi, C Lee, Y Chen, M Wei, S Li, S Dietmann, F Tang, X Li, MA Surani
    Cell Res., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  204. Effects of Aminoglycoside Antibiotics on Human Embryonic Stem Cell Viability during Differentiation In Vitro
    Authors: DS Varghese, S Parween, MT Ardah, BS Emerald, SA Ansari
    Stem Cells Int, 2017;2017(0):2451927.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  205. Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics
    Authors: NG Kooreman, PE de Almeida, JP Stack, RV Nelakanti, S Diecke, NY Shao, RJ Swijnenbur, V Sanchez-Fr, E Matsa, C Liu, AJ Connolly, JF Hamming, PHA Quax, MA Brehm, DL Greiner, LD Shultz, JC Wu
    Cell Rep, 2017;20(8):1978-1990.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  206. The syndrome of central hypothyroidism and macroorchidism: IGSF1 controls TRHR and FSHB expression by differential modulation of pituitary TGF? and Activin pathways
    Authors: M García, R Barrio, M García-Lav, AR Garcia-Ren, A Escudero, E Díaz-Rodrí, D Gorbenko D, A Fernández, YB de Rijke, E Vallespín, J Nevado, P Lapunzina, V Matre, PM Hinkle, AC Hokken-Koe, MP de Miguel, JM Cameselle-, M Nistal, CV Alvarez, JC Moreno
    Sci Rep, 2017;7(0):42937.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  207. Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells
    Authors: MG Perino, S Yamanaka, DR Riordon, Y Tarasova, KR Boheler
    PLoS ONE, 2017;12(12):e0188569.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  208. Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2
    Authors: N Cerdá-Este, H Naumann, S Ruzittu, N Mah, IM Pongrac, C Cozzitorto, A Hommel, MA Andrade-Na, E Bonifacio, FM Spagnoli
    Nat Commun, 2017;8(0):14127.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  209. Activin A more prominently regulates muscle mass in primates than does GDF8
    Authors: E Latres, J Mastaitis, W Fury, L Miloscio, J Trejos, J Pangilinan, H Okamoto, K Cavino, E Na, A Papatheodo, T Willer, Y Bai, J Hae Kim, A Rafique, S Jaspers, T Stitt, AJ Murphy, GD Yancopoulo, J Gromada
    Nat Commun, 2017;8(0):15153.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Surface Plasmon Resonance
  210. Insulin-producing cells derived from 'induced pluripotent stem cells' of patients with fulminant type 1 diabetes: vulnerability to cytokine insults and increased expression of apoptosis-related genes
    Authors: Y Hosokawa, T Toyoda, K Fukui, MY Baden, M Funato, Y Kondo, T Sudo, H Iwahashi, M Kishida, C Okada, A Watanabe, I Asaka, K Osafune, A Imagawa, I Shimomura
    J Diabetes Investig, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  211. Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration
    Authors: JS Saini, B Corneo, JD Miller, TR Kiehl, Q Wang, NC Boles, TA Blenkinsop, JH Stern, S Temple
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Development of a human cardiac organoid injury model reveals innate regenerative potential
    Authors: HK Voges, RJ Mills, DA Elliott, RG Parton, ER Porrello, JE Hudson
    Development, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  213. Rapid DNA replication origin licensing protects stem cell pluripotency
    Authors: JP Matson, R Dumitru, P Coryell, RM Baxley, W Chen, K Twaroski, BR Webber, J Tolar, AK Bielinsky, JE Purvis, JG Cook
    Elife, 2017;6(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Functional Thyroid Follicular Cells Differentiation from Human-Induced Pluripotent Stem Cells in Suspension Culture
    Authors: A Arauchi, K Matsuura, T Shimizu, T Okano
    Front Endocrinol (Lausanne), 2017;8(0):103.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  215. A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse
    Authors: B Ulmer, M Tingler, S Kurz, M Maerker, P Andre, D Mönch, M Campione, K Dei beta ler, M Lewandoski, T Thumberger, A Schweicker, A Fainsod, H Steinbei beta e, M Blum
    Sci Rep, 2017;7(0):43010.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  216. Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair
    Authors: M Tiburcy, JE Hudson, P Balfanz, S Schlick, T Meyer, ML Chang Liao, E Levent, F Raad, S Zeidler, E Wingender, J Riegler, M Wang, JD Gold, I Kehat, E Wettwer, U Ravens, P Dierickx, LW van Laake, MJ Goumans, S Khadjeh, K Toischer, G Hasenfuss, LA Couture, A Unger, WA Linke, T Araki, B Neel, G Keller, L Gepstein, JC Wu, WH Zimmermann
    Circulation, 2017;135(19):1832-1847.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Follistatin is a metastasis suppressor in a mouse model of HER2-positive breast cancer
    Authors: DD Seachrist, ST Sizemore, E Johnson, FW Abdul-Kari, KL Weber Bonk, RA Keri
    Breast Cancer Res., 2017;19(1):66.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  218. Physico-electrochemical Characterization of Pluripotent Stem Cells during Self-Renewal or Differentiation by a Multi-modal Monitoring System
    Authors: K Low, LY Wong, M Maldonado, C Manjunath, CB Horner, M Perez, NV Myung, J Nam
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
    Authors: F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier
    Nat Protoc, 2017;12(4):814-827.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Human ESC/iPSC-Derived Hepatocyte-like Cells Achieve Zone-Specific Hepatic Properties by Modulation of WNT Signaling
    Authors: S Mitani, K Takayama, Y Nagamoto, K Imagawa, F Sakurai, M Tachibana, R Sumazaki, H Mizuguchi
    Mol. Ther., 2017;25(6):1420-1433.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Acellular Mouse Kidney ECM can be Used as a Three-Dimensional Substrate to Test the Differentiation Potential of Embryonic Stem Cell Derived Renal Progenitors
    Authors: M Sambi, T Chow, J Whiteley, M Li, S Chua, V Raileanu, IM Rogers
    Stem Cell Rev, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  222. Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells
    Authors: A Asai, E Aihara, C Watson, R Mourya, T Mizuochi, P Shivakumar, K Phelan, C Mayhew, M Helmrath, T Takebe, J Wells, JA Bezerra
    Development, 2017;144(6):1056-1064.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  223. A pluripotent stem cell-based model for post-implantation human amniotic sac development
    Authors: Y Shao, K Taniguchi, RF Townshend, T Miki, DL Gumucio, J Fu
    Nat Commun, 2017;8(1):208.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  224. Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency
    Authors: YY Sin, PR Price, LL Ballantyne, CD Funk
    Sci Rep, 2017;7(1):2585.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  225. Differentiation and characterization of rhesus monkey atrial and ventricular cardiomyocytes from induced pluripotent stem cells
    Authors: X Zhang, H Cao, S Bai, W Huo, Y Ma
    Stem Cell Res, 2017;20(0):21-29.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  226. Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis
    Authors: NJ Palpant, Y Wang, B Hadland, RJ Zaunbreche, M Redd, D Jones, L Pabon, R Jain, J Epstein, WL Ruzzo, Y Zheng, I Bernstein, A Margolin, CE Murry
    Cell Rep, 2017;20(7):1597-1608.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  227. Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
    Authors: JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
    Cell Stem Cell, 2017;21(2):179-194.e4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  228. Direct comparison of distinct naive pluripotent states in human embryonic stem cells
    Authors: S Warrier, M Van der Je, G Duggal, L Tilleman, E Sutherland, J Taelman, M Popovic, S Lierman, S Chuva De S, A Van Soom, L Peelman, F Van Nieuwe, DIM De Coninck, B Menten, P Mestdagh, J Van de Som, D Deforce, P De Sutter, B Heindryckx
    Nat Commun, 2017;8(0):15055.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  229. Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols
    Authors: D Jeziorowsk, V Fontaine, C Jouve, E Villard, S Dussaud, D Akbar, V Letang, P Cervello, JM Itier, MP Pruniaux, JS Hulot
    Int J Mol Sci, 2017;18(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  230. Closed-channel culture system for efficient and reproducible differentiation of human pluripotent stem cells into islet cells
    Authors: K Hirano, S Konagaya, A Turner, Y Noda, S Kitamura, H Kotera, H Iwata
    Biochem. Biophys. Res. Commun., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  231. Are Adipose-Derived Stem Cells From Liver Falciform Ligaments Another Possible Source of Mesenchymal Stem Cells?
    Authors: SW Lee, JU Chong, SO Min, SY Bak, KS Kim
    Cell Transplant, 2017;26(5):855-866.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  232. Supraphysiological levels of GDF11 induce striated muscle atrophy
    Authors: DW Hammers, M Merscham-B, JY Hsiao, S Engst, JJ Hartman, HL Sweeney
    EMBO Mol Med, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  233. Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci
    Authors: EE Pashos, Y Park, X Wang, A Raghavan, W Yang, D Abbey, DT Peters, J Arbelaez, M Hernandez, N Kuperwasse, W Li, Z Lian, Y Liu, W Lv, SL Lytle-Gabb, DH Marchadier, P Rogov, J Shi, KJ Slovik, IM Stylianou, L Wang, R Yan, X Zhang, S Kathiresan, SA Duncan, TS Mikkelsen, EE Morrisey, DJ Rader, CD Brown, K Musunuru
    Cell Stem Cell, 2017;20(4):558-570.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Activin A Inhibits MPTP and LPS-Induced Increases in Inflammatory Cell Populations and Loss of Dopamine Neurons in the Mouse Midbrain In Vivo
    Authors: S Stayte, P Rentsch, AR Tr”scher, M Bamberger, KM Li, B Vissel
    PLoS ONE, 2017;12(1):e0167211.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  235. Cancer stem cells regulate cancer-associated fibroblasts via activation of Hedgehog signaling in mammary gland tumors
    Authors: G Valenti, HM Quinn, GJ Heynen, L Lan, JD Holland, R Vogel, A Wulf-Golde, W Birchmeier
    Cancer Res, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  236. In�Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling
    Authors: K Yamamizu, M Iwasaki, H Takakubo, T Sakamoto, T Ikuno, M Miyoshi, T Kondo, Y Nakao, M Nakagawa, H Inoue, JK Yamashita
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  237. Differentiation of cardiomyocytes and generation of human engineered heart tissue
    Authors: K Breckwoldt, D Letuffe-Br, I Mannhardt, T Schulze, B Ulmer, T Werner, A Benzin, B Klampe, MC Reinsch, S Laufer, A Shibamiya, M Prondzynsk, G Mearini, D Schade, S Fuchs, C Neuber, E Krämer, U Saleem, ML Schulze, ML Rodriguez, T Eschenhage, A Hansen
    Nat Protoc, 2017;12(6):1177-1197.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  238. Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes
    Authors: G Yücel, Z Zhao, I El-Battraw, H Lan, S Lang, X Li, F Buljubasic, WH Zimmermann, L Cyganek, J Utikal, U Ravens, T Wieland, M Borggrefe, XB Zhou, I Akin
    Sci Rep, 2017;7(1):2935.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  239. Modelling urea-cycle disorder citrullinemia type 1 with disease-specific iPSCs
    Authors: EY Yoshitoshi, T Toyoda, K Yasuda, M Kotaka, K Nomoto, K Okita, K Yasuchika, S Okamoto, N Takubo, T Nishikubo, T Soga, S Uemoto, K Osafune
    Biochem. Biophys. Res. Commun, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Higher-Order Kidney Organogenesis from Pluripotent Stem Cells
    Authors: A Taguchi, R Nishinakam
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  241. Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-wide Genetic Screening
    Authors: ZQ He, BL Xia, YK Wang, J Li, GH Feng, LL Zhang, YH Li, HF Wan, TD Li, K Xu, XW Yuan, YF Li, XX Zhang, Y Zhang, L Wang, W Li, Q Zhou
    Cell Rep, 2017;20(9):2227-2237.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  242. The N-glycome of embryonic stem cells and thereof differentiated hepatic cells
    Authors: H Montacir, N Freyer, F Knoespel, T Urbaniak, T Dedova, M Berger, G Damm, R Tauber, K Zeilinger, V Blanchard
    Chembiochem, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  243. Thrombospondin-1 (TSP-1), a new bone morphogenetic protein-2 and -4 (BMP-2/4) antagonist identified in pituitary cells
    Authors: C Sallon, I Callebaut, I Boulay, J Fontaine, D Logeart-Av, C Henriquet, M Pugnière, X Cayla, P Monget, G Harichaux, V Labas, S Canepa, C Taragnat
    J. Biol. Chem., 2017;0(0):.
    Species: Ovine
    Sample Types: Whole Cells
    Applications: Bioassay
  244. Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva
    Authors: K Hino, K Horigome, M Nishio, S Komura, S Nagata, C Zhao, Y Jin, K Kawakami, Y Yamada, A Ohta, J Toguchida, M Ikeya
    J. Clin. Invest., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  245. Accreditation of Biosafe Clinical-Grade Human Embryonic Stem Cells According to Chinese Regulations
    Authors: Q Gu, J Wang, L Wang, ZX Liu, WW Zhu, YQ Tan, WF Han, J Wu, CJ Feng, JH Fang, L Liu, L Wang, W Li, XY Zhao, BY Hu, J Hao, Q Zhou
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  246. Nutritional modulation of mouse and human liver bud growth through a branched-amino acid metabolism
    Authors: H Koike, RR Zhang, Y Ueno, K Sekine, YW Zheng, T Takebe, H Taniguchi
    Development, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  247. Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
    Authors: KF Cogger, A Sinha, F Sarangi, EC McGaugh, D Saunders, C Dorrell, S Mejia-Guer, Y Aghazadeh, JL Rourke, RA Screaton, M Grompe, PR Streeter, AC Powers, M Brissova, T Kislinger, MC Nostro
    Nat Commun, 2017;8(1):331.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  248. Activin signaling is an essential component of the TGF-? induced pro-metastatic phenotype in colorectal cancer
    Authors: JJ Staudacher, J Bauer, A Jana, J Tian, T Carroll, G Mancinelli, Ö Özden, N Krett, G Guzman, D Kerr, P Grippo, B Jung
    Sci Rep, 2017;7(1):5569.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  249. In Vitro Micropatterned Human Pluripotent Stem Cell Test (�P-hPST) for Morphometric-Based Teratogen Screening
    Authors: J Xing, Y Cao, Y Yu, H Li, Z Song, H Yu
    Sci Rep, 2017;7(1):8491.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  250. Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency
    Authors: M Sone, N Morone, T Nakamura, A Tanaka, K Okita, K Woltjen, M Nakagawa, JE Heuser, Y Yamada, S Yamanaka, T Yamamoto
    Cell Metab., 2017;25(5):1103-1117.e6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Identification of ligand-selective peptidic ActRIIB-antagonists using phage display technology
    Authors: K Sakamoto, Y Kanematsu-, Y Kamada, M Oka, T Ohnishi, M Miwa, T Asami, H Inooka
    Biochem Biophys Rep, 2017;11(0):33-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  252. Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate
    Authors: AG Freire, A Waghray, F Soares-da-, TP Resende, DF Lee, CF Pereira, DS Nascimento, IR Lemischka, P Pinto-do-Ó
    Stem Cell Reports, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  253. Development of hepatoma-derived, bidirectional oval-like cells as a model to study host interactions with hepatitis C virus during differentiation
    Authors: M Ito, S Sun, T Fukuhara, R Suzuki, M Tamai, T Yamauchi, K Nakashima, YI Tagawa, S Okazaki, Y Matsuura, T Wakita, T Suzuki
    Oncotarget, 2017;8(33):53899-53915.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  254. Activin Receptor Type IIA (ACVR2A) Functions Directly in Osteoblasts as a Negative Regulator of Bone Mass
    Authors: BC Goh, V Singhal, AJ Herrera, RE Tomlinson, S Kim, MC Faugere, EL Germain-Le, TL Clemens, SJ Lee, DJ DiGirolamo
    J. Biol. Chem., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  255. Transplantation of multipotent Isl1+ cardiac progenitor cells preserves infarcted heart function in mice
    Authors: Y Li, S Tian, I Lei, L Liu, P Ma, Z Wang
    Am J Transl Res, 2017;9(3):1530-1542.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  256. The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes
    Authors: N Merienne, G Vachey, L de Longpre, C Meunier, V Zimmer, G Perriard, M Canales, A Mathias, L Herrgott, T Beltramine, A Maulet, T Dequesne, C Pythoud, M Rey, L Pellerin, E Brouillet, AL Perrier, R du Pasquie, N Déglon
    Cell Rep, 2017;20(12):2980-2991.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  257. Hypoxia-induced activin A diminishes endothelial cell vasculogenic activity
    Authors: S Merfeld-Cl, H Lu, X Wu, KL March, DO Traktuev
    J. Cell. Mol. Med., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  258. Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells
    Authors: JA Heslop, R Kia, CS Pridgeon, RL Sison-Youn, T Liloglou, M Elmasry, SW Fenwick, JS Mills, NR Kitteringh, CE Goldring, BK Park
    Stem Cells Transl Med, 2017;6(5):1321-1331.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  259. Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses
    Authors: S Tousa, M Semitekolo, I Morianos, A Banos, AI Trochoutso, TM Brodie, N Poulos, K Samitas, M Kapasa, D Konstantop, G Paraskevop, M Gaga, CM Hawrylowic, F Sallusto, G Xanthou
    Proc. Natl. Acad. Sci. U.S.A, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  260. Magnetic Targeting of Stem Cell Derivatives Enhances Hepatic Engraftment into Structurally Normal Liver
    Authors: WS Fagg, N Liu, MJ Yang, K Cheng, E Chung, JS Kim, G Wu, J Fair
    Cell Transplant, 2017;26(12):1868-1877.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  261. Adrenergic receptor agonists induce the differentiation of pluripotent stem cell-derived hepatoblasts into hepatocyte-like cells
    Authors: M Kotaka, T Toyoda, K Yasuda, Y Kitano, C Okada, A Ohta, A Watanabe, M Uesugi, K Osafune
    Sci Rep, 2017;7(1):16734.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  262. Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
    Authors: M Crespo, E Vilar, SY Tsai, K Chang, S Amin, T Srinivasan, T Zhang, NH Pipalia, HJ Chen, M Witherspoo, M Gordillo, JZ Xiang, FR Maxfield, S Lipkin, T Evans, S Chen
    Nat. Med., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Activin A/Smads signaling pathway negatively regulates Oxygen Glucose Deprivation-induced autophagy via suppression of JNK and p38 MAPK pathways in neuronal PC12 cells
    Authors: Long-Xing Xue
    Biochem. Biophys. Res. Commun, 2016;480(3):355-361.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  264. Fscn1 is required for the trafficking of TGF-? family type I receptors during endoderm formation
    Nat Commun, 2016;7(0):12603.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  265. Nemo-like kinase 1 (Nlk1) and paraxial protocadherin (PAPC) cooperatively control Xenopus gastrulation through regulation of Wnt/planar cell polarity (PCP) signaling
    Authors: Lilian T Kaufmann
    Differentiation, 2016;93(0):27-38.
    Applications: Bioassay
  266. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
    Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
    Nat. Med., 2016;22(12):1421-1427.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  267. Automated image analysis with the potential for process quality control applications in stem cell maintenance and differentiation
    Authors: Robert Thomas
    Biotechnol. Prog., 2016;32(1):215-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  268. The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells
    Authors: Joan Massagué
    Cell Stem Cell, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  269. Transplantation of Donor-Origin Mouse Embryonic Stem Cell-Derived Thymic Epithelial Progenitors Prevents the Development of Chronic Graft-Versus-Host Disease in Mice
    Stem Cells Transl Med, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  270. In�Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts
    Authors: S Kadota, L Pabon, H Reinecke, CE Murry
    Stem Cell Reports, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  271. Repressed SIRT1/PGC-1? pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration
    J Transl Med, 2016;14(1):344.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  272. Heparin Promotes Cardiac Differentiation of Human Pluripotent Stem Cells in Chemically Defined Albumin-Free Medium, Enabling Consistent Manufacture of Cardiomyocytes
    Stem Cells Transl Med, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  273. Transient RUNX1 Expression during Early Mesendodermal Differentiation of�hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling
    Stem Cell Reports, 2016;7(5):884-896.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  274. TAZ induction directs differentiation of thyroid follicular cells from human embryonic stem cells
    Authors: Terry F Davies
    Thyroid, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
  275. miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification
    Proc Natl Acad Sci USA, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  276. Activin A programs the differentiation of human TFH cells
    Nat Immunol, 2016;17(8):976-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  277. A strategy to ensure safety of stem cell-derived retinal pigment epithelium cells
    Stem Cell Res Ther, 2016;7(1):127.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  278. Dynamic Heterogeneity of Brachyury in Mouse Epiblast Stem Cells Mediates Distinct Response to Extrinsic Bone Morphogenetic Protein (BMP) Signaling
    Authors: L Song, J Chen, G Peng, K Tang, N Jing
    J. Biol. Chem., 2016;291(29):15212-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  279. Activin promotes skin carcinogenesis by attraction and reprogramming of macrophages
    EMBO Mol Med, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  280. SMAD3 Regulates Follicle-Stimulating Hormone Synthesis by Pituitary Gonadotrope Cells In Vivo
    Authors: Yining Li
    J. Biol. Chem, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  281. Growth hormone is permissive for neoplastic colon growth
    Proc Natl Acad Sci USA, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  282. Lin28 is induced in primed embryonic stem cells and regulates let-7-independent events
    Authors: Silvia Parisi
    FASEB J, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  283. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling
    Stem Cell Res Ther, 2016;7(1):115.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells
    PLoS ONE, 2016;11(7):e0159246.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  285. Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose
    PLoS ONE, 2016;11(9):e0163580.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  286. Small C-terminal Domain Phosphatase 3 Dephosphorylates the Linker Sites of Receptor-regulated Smads (R-Smads) to Ensure Transforming Growth Factor beta (TGFbeta)-mediated Germ Layer Induction in Xenopus Embryos.
    Authors: Sun G, Hu Z, Min Z, Yan X, Guan Z, Su H, Fu Y, Ma X, Chen Y, Zhang M, Tao Q, Wu W
    J Biol Chem, 2015;290(28):17239-49.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  287. The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells.
    Authors: Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D'Souza S, Snoeck H
    Nat Protoc, 2015;10(3):413-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  288. Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure.
    Authors: Calderon-Gierszal E, Prins G
    PLoS ONE, 2015;10(7):e0133238.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  289. Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells.
    Authors: Yang W, Liu Y, Slovik K, Wu J, Duncan S, Rader D, Morrisey E
    PLoS ONE, 2015;10(8):e0134995.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  290. DNA methylation directs functional maturation of pancreatic beta cells.
    Authors: Dhawan S, Tschen S, Zeng C, Guo T, Hebrok M, Matveyenko A, Bhushan A
    J Clin Invest, 2015;125(7):2851-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells.
    Authors: Iyer D, Gambardella L, Bernard W, Serrano F, Mascetti V, Pedersen R, Talasila A, Sinha S
    Development, 2015;142(8):1528-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  292. Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile.
    Authors: Sugawa F, Arauzo-Bravo M, Yoon J, Kim K, Aramaki S, Wu G, Stehling M, Psathaki O, Hubner K, Scholer H
    EMBO J, 2015;34(8):1009-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  293. Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells.
    Authors: Nagaoka M, Kobayashi M, Kawai C, Mallanna S, Duncan S
    PLoS ONE, 2015;10(8):e0136350.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  294. Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice.
    Authors: Latres E, Pangilinan J, Miloscio L, Bauerlein R, Na E, Potocky T, Huang Y, Eckersdorff M, Rafique A, Mastaitis J, Lin C, Murphy A, Yancopoulos G, Gromada J, Stitt T
    Skelet Muscle, 2015;5(0):34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  295. Forced expression of Nanog or Esrrb preserves the ESC status in the absence of nucleostemin expression.
    Authors: Katano M, Ema M, Nakachi Y, Mizuno Y, Hirasaki M, Suzuki A, Ueda A, Nishimoto M, Takahashi S, Okazaki Y, Okuda A
    Stem Cells, 2015;33(4):1089-101.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  296. Activin Regulates Self-renewal and Differentiation of Trophoblast Stem Cells by Down-regulating the X Chromosome Gene Bcor.
    Authors: Zhu G, Fei T, Li Z, Yan X, Chen Y
    J Biol Chem, 2015;290(36):22019-29.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  297. Nephron organoids derived from human pluripotent stem cells model kidney development and injury.
    Authors: Morizane R, Lam A, Freedman B, Kishi S, Valerius M, Bonventre J
    Nat Biotechnol, 2015;33(11):1193-200.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  298. Transcription factor binding dynamics during human ES cell differentiation.
    Authors: Tsankov, Alexande, Gu, Hongcang, Akopian, Veronika, Ziller, Michael, Donaghey, Julie, Amit, Ido, Gnirke, Andreas, Meissner, Alexande
    Nature, 2015;518(7539):344-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  299. Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes.
    Authors: Galvagni F, Lentucci C, Neri F, Dettori D, De Clemente C, Orlandini M, Anselmi F, Rapelli S, Grillo M, Borghi S, Oliviero S
    Stem Cells, 2015;33(3):742-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  300. Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1.
    Authors: Majumder A, Syed K, Joseph S, Scambler P, Dutta D
    J Biol Chem, 2015;290(21):13053-63.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  301. Adipose Stromal Cell Contact with Endothelial Cells Results in Loss of Complementary Vasculogenic Activity Mediated by Induction of Activin A.
    Authors: Merfeld-Clauss S, Lupov I, Lu H, March K, Traktuev D
    Stem Cells, 2015;33(10):3039-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  302. Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis.
    Authors: Kim M, Horst A, Blinka S, Stamm K, Mahnke D, Schuman J, Gundry R, Tomita-Mitchell A, Lough J
    PLoS ONE, 2015;10(2):e0118670.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  303. Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo.
    Authors: Krawchuk D, Anani S, Honma-Yamanaka N, Polito S, Shafik M, Yamanaka Y
    J Cell Sci, 2015;128(5):1011-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  304. Reprogramming of HUVECs into induced pluripotent stem cells (HiPSCs), generation and characterization of HiPSC-derived neurons and astrocytes.
    Authors: Haile, Yohannes, Nakhaei-Nejad, Maryam, Boakye, Paul A, Baker, Glen, Smith, Peter A, Murray, Allan G, Giuliani, Fabrizio, Jahroudi, Nadia
    PLoS ONE, 2015;10(3):e0119617.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  305. Induction of tissue-specific stem cells by reprogramming factors, and tissue-specific selection.
    Authors: Noguchi, H, Saitoh, I, Tsugata, T, Kataoka, H, Watanabe, M, Noguchi, Y
    Cell Death Differ, 2015;22(1):145-55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  306. Increased culture density is linked to decelerated proliferation, prolonged G1 phase, and enhanced propensity for differentiation of self-renewing human pluripotent stem cells.
    Authors: Wu J, Fan Y, Tzanakakis E
    Stem Cells Dev, 2015;24(7):892-903.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  307. Follistatin288 Regulates Germ Cell Cyst Breakdown and Primordial Follicle Assembly in the Mouse Ovary.
    Authors: Wang Z, Niu W, Wang Y, Teng Z, Wen J, Xia G, Wang C
    PLoS ONE, 2015;10(6):e0129643.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  308. DMSO efficiently down regulates pluripotency genes in human embryonic stem cells during definitive endoderm derivation and increases the proficiency of hepatic differentiation.
    Authors: Czysz, Katherin, Minger, Stephen, Thomas, Nick
    PLoS ONE, 2015;10(2):e0117689.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  309. Activin A inhibits RANKL-mediated osteoclast formation, movement and function in murine bone marrow macrophage cultures.
    Authors: Fowler T, Kamalakar A, Akel N, Kurten R, Suva L, Gaddy D
    J Cell Sci, 2015;128(4):683-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  310. Resveratrol ameliorates the maturation process of beta-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells.
    Authors: Pezzolla D, Lopez-Beas J, Lachaud C, Dominguez-Rodriguez A, Smani T, Hmadcha A, Soria B
    PLoS ONE, 2015;10(3):e0119904.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  311. Generation of articular chondrocytes from human pluripotent stem cells.
    Authors: Craft A, Rockel J, Nartiss Y, Kandel R, Alman B, Keller G
    Nat Biotechnol, 2015;33(6):638-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  312. Enhanced Electrical Integration of Engineered Human Myocardium via Intramyocardial versus Epicardial Delivery in Infarcted Rat Hearts.
    Authors: Gerbin K, Yang X, Murry C, Coulombe K
    PLoS ONE, 2015;10(7):e0131446.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis.
    Authors: Bufalino A, Cervigne N, de Oliveira C, Fonseca F, Rodrigues P, Macedo C, Sobral L, Miguel M, Lopes M, Paes Leme A, Lambert D, Salo T, Kowalski L, Graner E, Coletta R
    PLoS ONE, 2015;10(8):e0136599.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  314. Overexpression of activin-A and -B in malignant mesothelioma - attenuated Smad3 signaling responses and ERK activation promote cell migration and invasive growth.
    Authors: Tamminen J, Yin M, Ronty M, Sutinen E, Pasternack A, Ritvos O, Myllarniemi M, Koli K
    Exp Cell Res, 2015;332(1):102-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  315. Signalling Through Retinoic Acid Receptors is Required for Reprogramming of Both Mouse Embryonic Fibroblast Cells and Epiblast Stem Cells to Induced Pluripotent Stem Cells.
    Authors: Yang J, Wang W, Ooi J, Campos L, Lu L, Liu P
    Stem Cells, 2015;33(5):1390-404.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  316. The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy.
    Authors: Ohsawa Y, Takayama K, Nishimatsu S, Okada T, Fujino M, Fukai Y, Murakami T, Hagiwara H, Itoh F, Tsuchida K, Hayashi Y, Sunada Y
    PLoS ONE, 2015;10(7):e0133713.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  317. HEB associates with PRC2 and SMAD2/3 to regulate developmental fates.
    Authors: Yoon, Se-Jin, Foley, Joseph W, Baker, Julie C
    Nat Commun, 2015;6(0):6546.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  318. Activin receptor signaling regulates cocaine-primed behavioral and morphological plasticity.
    Authors: Gancarz A, Wang Z, Schroeder G, Damez-Werno D, Braunscheidel K, Mueller L, Humby M, Caccamise A, Martin J, Dietz K, Neve R, Dietz D
    Nat Neurosci, 2015;18(7):959-61.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  319. The differential anti-tumour effects of zoledronic acid in breast cancer - evidence for a role of the activin signaling pathway.
    Authors: Wilson C, Ottewell P, Coleman R, Holen I
    BMC Cancer, 2015;15(0):55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Alternative Routes to Induce Naive Pluripotency in Human Embryonic Stem Cells.
    Authors: Duggal G, Warrier S, Ghimire S, Broekaert D, Van der Jeught M, Lierman S, Deroo T, Peelman L, Van Soom A, Cornelissen R, Menten B, Mestdagh P, Vandesompele J, Roost M, Slieker R, Heijmans B, Deforce D, De Sutter P, de Sousa Lopes S, Heindryckx B
    Stem Cells, 2015;33(9):2686-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  321. In vitro generation of human pluripotent stem cell derived lung organoids.
    Authors: Dye, Briana R, Hill, David R, Ferguson, Michael, Tsai, Yu-Hwai, Nagy, Melinda, Dyal, Rachel, Wells, James M, Mayhew, Christop, Nattiv, Roy, Klein, Ophir D, White, Eric S, Deutsch, Gail H, Spence, Jason R
    Elife, 2015;4(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  322. Activin A protects midbrain neurons in the 6-hydroxydopamine mouse model of Parkinson's disease.
    Authors: Stayte S, Rentsch P, Li K, Vissel B
    PLoS ONE, 2015;10(4):e0124325.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  323. Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells.
    Authors: Liu Y, Kaneda R, Leja T, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz R, Barahona M, Schneider M
    Stem Cells, 2014;32(6):1515-26.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  324. An activin receptor IIA ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobin.
    Authors: Carrancio S, Markovics J, Wong P, Leisten J, Castiglioni P, Groza M, Raymon H, Heise C, Daniel T, Chopra R, Sung V
    Br J Haematol, 2014;165(6):870-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  325. Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer.
    Authors: Togashi, Yosuke, Sakamoto, Hiroki, Hayashi, Hidetosh, Terashima, Masato, de Velasco, Marco A, Fujita, Yoshihik, Kodera, Yasuo, Sakai, Kazuko, Tomida, Shuta, Kitano, Masayuki, Ito, Akihiko, Kudo, Masatosh, Nishio, Kazuto
    Mol Cancer, 2014;13(0):126.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  326. In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity.
    Authors: Gouti, Mina, Tsakiridis, Anestis, Wymeersch, Filip J, Huang, Yali, Kleinjung, Jens, Wilson, Valerie, Briscoe, James
    PLoS Biol, 2014;12(8):e1001937.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  327. A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium.
    Authors: Ferrer M, Corneo B, Davis J, Wan Q, Miyagishima K, King R, Maminishkis A, Marugan J, Sharma R, Shure M, Temple S, Miller S, Bharti K
    Stem Cells Transl Med, 2014;3(8):911-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  328. Prohibitin 2 regulates the proliferation and lineage-specific differentiation of mouse embryonic stem cells in mitochondria.
    Authors: Kowno, Megumi, Watanabe-Susaki, Kanako, Ishimine, Hisako, Komazaki, Shinji, Enomoto, Kei, Seki, Yasuhiro, Wang, Ying Yin, Ishigaki, Yohei, Ninomiya, Naoto, Noguchi, Taka-aki, Kokubu, Yuko, Ohnishi, Keigoh, Nakajima, Yoshiro, Kato, Kaoru, Intoh, Atsushi, Takada, Hitomi, Yamakawa, Norio, Wang, Pi-Chao, Asashima, Makoto, Kurisaki, Akira
    PLoS ONE, 2014;9(4):e81552.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  329. Nodal.Gdf1 heterodimers with bound prodomains enable serum-independent nodal signaling and endoderm differentiation.
    Authors: Fuerer C, Nostro M, Constam D
    J Biol Chem, 2014;289(25):17854-71.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  330. A synthetic peptide-acrylate surface for production of insulin-producing cells from human embryonic stem cells.
    Authors: Lin P, Hung S, Yang Y, Liao L, Hsieh Y, Yen H, Lu H, Lee M, Chu I, Hwang S
    Stem Cells Dev, 2014;23(4):372-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  331. Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant.
    Authors: Takebe, Takanori, Zhang, Ran-Ran, Koike, Hiroyuki, Kimura, Masaki, Yoshizawa, Emi, Enomura, Masahiro, Koike, Naoto, Sekine, Keisuke, Taniguchi, Hideki
    Nat Protoc, 2014;9(2):396-409.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  332. Cobalt protoporphyrin pretreatment protects human embryonic stem cell-derived cardiomyocytes from hypoxia/reoxygenation injury in vitro and increases graft size and vascularization in vivo.
    Authors: Luo J, Weaver M, Cao B, Dennis J, Van Biber B, Laflamme M, Allen M
    Stem Cells Transl Med, 2014;3(6):734-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  333. Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes.
    Authors: Dambrot C, Braam S, Tertoolen L, Birket M, Atsma D, Mummery C
    J Cell Mol Med, 2014;18(8):1509-18.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  334. TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
    Authors: Suresh Babu S, Valdez Y, Xu A, O'Byrne A, Calvo F, Lei V, Conway E
    BMC Cancer, 2014;14(0):113.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  335. Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells.
    Authors: Taguchi A, Kaku Y, Ohmori T, Sharmin S, Ogawa M, Sasaki H, Nishinakamura R
    Cell Stem Cell, 2014;14(1):53-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  336. Pancreatic insulin-producing cells differentiated from human embryonic stem cells correct hyperglycemia in SCID/NOD mice, an animal model of diabetes.
    Authors: Hua X, Wang Y, Tang Y, Yu S, Jin S, Meng X, Li H, Liu F, Sun Q, Wang H, Li J
    PLoS ONE, 2014;9(7):e102198.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  337. Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment.
    Authors: Seth A, Ye J, Yu N, Guez F, Bedford D, Neale G, Cordi S, Brindle P, Lemaigre F, Kaestner K, Sosa-Pineda B
    Development, 2014;141(3):538-47.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  338. Efficient and rapid induction of human iPSCs/ESCs into nephrogenic intermediate mesoderm using small molecule-based differentiation methods.
    Authors: Araoka, Toshikaz, Mae, Shin-ich, Kurose, Yuko, Uesugi, Motonari, Ohta, Akira, Yamanaka, Shinya, Osafune, Kenji
    PLoS ONE, 2014;9(1):e84881.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  339. Polycomb group protein expression during differentiation of human embryonic stem cells into pancreatic lineage in vitro.
    Authors: Pethe, Prasad, Nagvenkar, Punam, Bhartiya, Deepa
    BMC Cell Biol, 2014;15(0):18.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  340. Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency.
    Authors: Onishi K, Tonge P, Nagy A, Zandstra P
    Stem Cell Reports, 2014;3(1):156-68.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  341. Ethanol negatively regulates hepatic differentiation of hESC by inhibition of the MAPK/ERK signaling pathway in vitro.
    Authors: Gao W, Zhou P, Ma X, Tschudy-Seney B, Chen J, Magner N, Revzin A, Nolta J, Zern M, Duan Y
    PLoS ONE, 2014;9(11):e112698.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  342. Hanging drop cultures of human testis and testis cancer samples: a model used to investigate activin treatment effects in a preserved niche.
    Authors: Jorgensen A, Young J, Nielsen J, Joensen U, Toft B, Rajpert-De Meyts E, Loveland K
    Br J Cancer, 2014;110(10):2604-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  343. Follicle-stimulating hormone synthesis and fertility are intact in mice lacking SMAD3 DNA binding activity and SMAD2 in gonadotrope cells.
    Authors: Fortin J, Boehm U, Weinstein M, Graff J, Bernard D
    FASEB J, 2014;28(3):1474-85.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  344. Efficient generation of lung and airway epithelial cells from human pluripotent stem cells.
    Authors: Huang, Sarah X, Islam, Mohammad, O'Neill, John, Hu, Zheng, Yang, Yong-Gua, Chen, Ya-Wen, Mumau, Melanie, Green, Michael, Vunjak-Novakovic, Gordana, Bhattacharya, Jahar, Snoeck, Hans-Wil
    Nat Biotechnol, 2014;32(1):84-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  345. Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium.
    Authors: Turnbull I, Karakikes I, Serrao G, Backeris P, Lee J, Xie C, Senyei G, Gordon R, Li R, Akar F, Hajjar R, Hulot J, Costa K
    FASEB J, 2014;28(2):644-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  346. sRNA-seq analysis of human embryonic stem cells and definitive endoderm reveals differentially expressed microRNAs and novel IsomiRs with distinct targets.
    Authors: Hinton A, Hunter S, Afrikanova I, Jones G, Lopez A, Fogel G, Hayek A, King C
    Stem Cells, 2014;32(9):2360-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  347. A modified EpiSC culture condition containing a GSK3 inhibitor can support germline-competent pluripotency in mice.
    Authors: Tsukiyama, Tomoyuki, Ohinata, Yasuhide
    PLoS ONE, 2014;9(4):e95329.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  348. Signaling by the extracellular matrix protein Reelin promotes granulosa cell proliferation in the chicken follicle.
    Authors: Eresheim, Christin, Leeb, Christia, Buchegger, Patricia, Nimpf, Johannes
    J Biol Chem, 2014;289(14):10182-91.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  349. Molecular beacon-enabled purification of living cells by targeting cell type-specific mRNAs.
    Authors: Wile B, Ban K, Yoon Y, Bao G
    Nat Protoc, 2014;9(10):2411-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  350. Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers.
    Authors: Lam A, Freedman B, Morizane R, Lerou P, Valerius M, Bonventre J
    J Am Soc Nephrol, 2014;25(6):1211-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  351. HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin.
    Authors: Watanabe, Hitoshi, Takayama, Kazuo, Inamura, Mitsuru, Tachibana, Masashi, Mimura, Natsumi, Katayama, Kazufumi, Tashiro, Katsuhis, Nagamoto, Yasuhito, Sakurai, Fuminori, Kawabata, Kenji, Furue, Miho Kus, Mizuguchi, Hiroyuki
    PLoS ONE, 2014;9(3):e90791.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  352. Alteration of skin wound healing in keratinocyte-specific mediator complex subunit 1 null mice.
    Authors: Noguchi F, Nakajima T, Inui S, Reddy J, Itami S
    PLoS ONE, 2014;9(8):e102271.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  353. High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells.
    Authors: Hakim F, Kaitsuka T, Raeed J, Wei F, Shiraki N, Akagi T, Yokota T, Kume S, Tomizawa K
    J Biol Chem, 2014;289(14):9623-38.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  354. Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity.
    Authors: Guo T, Marmol P, Moliner A, Bjornholm M, Zhang C, Shokat K, Ibanez C
    Elife, 2014;3(0):e03245.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  355. CCAAT/enhancer binding protein-mediated regulation of TGFbeta receptor 2 expression determines the hepatoblast fate decision.
    Authors: Takayama K, Kawabata K, Nagamoto Y, Inamura M, Ohashi K, Okuno H, Yamaguchi T, Tashiro K, Sakurai F, Hayakawa T, Okano T, Furue M, Mizuguchi H
    Development, 2014;141(1):91-100.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  356. Enzyme-free passage of human pluripotent stem cells by controlling divalent cations.
    Authors: Ohnuma, Kiyoshi, Fujiki, Ayaka, Yanagihara, Kana, Tachikawa, Saoko, Hayashi, Yohei, Ito, Yuzuru, Onuma, Yasuko, Chan, Techuan, Michiue, Tatsuo, Furue, Miho K, Asashima, Makoto
    Sci Rep, 2014;4(0):4646.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  357. Enabling autologous human liver regeneration with differentiated adipocyte stem cells.
    Authors: Xu, Dan, Nishimura, Toshihik, Zheng, Ming, Wu, Manhong, Su, Hua, Sato, Noboru, Lee, Gordon, Michie, Sara, Glenn, Jeffrey, Peltz, Gary
    Cell Transplant, 2014;23(12):1573-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  358. The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways.
    Authors: Zhu Q, Song L, Peng G, Sun N, Chen J, Zhang T, Sheng N, Tang W, Qian C, Qiao Y, Tang K, Han J, Li J, Jing N
    Elife, 2014;3(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  359. Generation of organized germ layers from a single mouse embryonic stem cell.
    Authors: Poh Y, Chen J, Hong Y, Yi H, Zhang S, Chen J, Wu D, Wang L, Jia Q, Singh R, Yao W, Tan Y, Tajik A, Tanaka T, Wang N
    Nat Commun, 2014;5(0):4000.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  360. Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors.
    Authors: Kaitsuka T, Noguchi H, Shiraki N, Kubo T, Wei F, Hakim F, Kume S, Tomizawa K
    Stem Cells Transl Med, 2014;3(1):114-27.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  361. Defined human pluripotent stem cell culture enables highly efficient neuroepithelium derivation without small molecule inhibitors.
    Authors: Lippmann E, Estevez-Silva M, Ashton R
    Stem Cells, 2014;32(4):1032-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  362. Efficient programming of human eye conjunctiva-derived induced pluripotent stem (ECiPS) cells into definitive endoderm-like cells.
    Authors: Massumi M, Hoveizi E, Baktash P, Hooti A, Ghazizadeh L, Nadri S, Pourasgari F, Hajarizadeh A, Soleimani M, Nabiuni M, Khorramizadeh M
    Exp Cell Res, 2014;322(1):51-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  363. Derivation and expansion of PAX7-positive muscle progenitors from human and mouse embryonic stem cells.
    Authors: Shelton M, Metz J, Liu J, Carpenedo R, Demers S, Stanford W, Skerjanc I
    Stem Cell Reports, 2014;3(3):516-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  364. Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.
    Authors: Chong J, Yang X, Don C, Minami E, Liu Y, Weyers J, Mahoney W, Van Biber B, Cook S, Palpant N, Gantz J, Fugate J, Muskheli V, Gough G, Vogel K, Astley C, Hotchkiss C, Baldessari A, Pabon L, Reinecke H, Gill E, Nelson V, Kiem H, Laflamme M, Murry C
    Nature, 2014;510(7504):273-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  365. A single-cell and feeder-free culture system for monkey embryonic stem cells.
    Authors: Ono T, Suzuki Y, Kato Y, Fujita R, Araki T, Yamashita T, Kato H, Torii R, Sato N
    PLoS ONE, 2014;9(2):e88346.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  366. Unsaturated fatty acids disrupt Smad signaling in gonadotrope cells leading to inhibition of FSHbeta gene expression.
    Authors: Garrel G, Simon V, Denoyelle C, Ishaq M, Rouch C, Dairou J, Magnan C, Migrenne S, Cruciani-Guglielmacci C, Cohen-Tannoudji J
    Endocrinology, 2014;155(2):592-604.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  367. Molecular evidence for OCT4-induced plasticity in adult human fibroblasts required for direct cell fate conversion to lineage specific progenitors.
    Authors: Mitchell R, Szabo E, Shapovalova Z, Aslostovar L, Makondo K, Bhatia M
    Stem Cells, 2014;32(8):2178-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  368. KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development.
    Authors: Goldman O, Han S, Sourisseau M, Dziedzic N, Hamou W, Corneo B, D'Souza S, Sato T, Kotton D, Bissig K, Kalir T, Jacobs A, Evans T, Evans M, Gouon-Evans V
    Cell Stem Cell, 2013;12(6):748-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  369. Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.
    Authors: Brafman D, Phung C, Kumar N, Willert K
    Cell Death Differ, 2013;20(3):369-81.
  370. Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential.
    Authors: Duggal G, Heindryckx B, Warrier S, O'Leary T, Van der Jeught M, Lierman S, Vossaert L, Deroo T, Deforce D, Chuva de Sousa Lopes S, De Sutter P
    Stem Cells Dev, 2013;22(23):3141-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  371. Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium.
    Authors: Buchholz, David E, Pennington, Britney, Croze, Roxanne, Hinman, Cassidy, Coffey, Peter J, Clegg, Dennis O
    Stem Cells Transl Med, 2013;2(5):384-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  372. Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells.
    Authors: White M, Rufaihah A, Liu L, Ghebremariam Y, Ivey K, Cooke J, Srivastava D
    Stem Cells, 2013;31(1):92-103.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  373. Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells.
    Authors: Mae, Shin-Ich, Shono, Akemi, Shiota, Fumihiko, Yasuno, Tetsuhik, Kajiwara, Masatosh, Gotoda-Nishimura, Nanaka, Arai, Sayaka, Sato-Otubo, Aiko, Toyoda, Taro, Takahashi, Kazutosh, Nakayama, Naoki, Cowan, Chad A, Aoi, Takashi, Ogawa, Seishi, McMahon, Andrew P, Yamanaka, Shinya, Osafune, Kenji
    Nat Commun, 2013;4(0):1367.
  374. Human embryonic stem cells differentiate into functional renal proximal tubular-like cells.
    Authors: Narayanan, Karthike, Schumacher, Karl M, Tasnim, Farah, Kandasamy, Karthike, Schumacher, Annegret, Ni, Ming, Gao, Shujun, Gopalan, Began, Zink, Daniele, Ying, Jackie Y
    Kidney Int, 2013;83(4):593-603.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  375. Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification.
    Authors: Hoffman J, Wu C, Merrill B
    Development, 2013;140(8):1665-75.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  376. Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays.
    Authors: Navarrete E, Liang P, Lan F, Sanchez-Freire V, Simmons C, Gong T, Sharma A, Burridge P, Patlolla B, Lee A, Wu H, Beygui R, Wu S, Robbins R, Bers D, Wu J
    Circulation, 2013;128(11):S3-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  377. Cell-cycle control of developmentally regulated transcription factors accounts for heterogeneity in human pluripotent cells.
    Authors: Singh A, Chappell J, Trost R, Lin L, Wang T, Tang J, Matlock B, Weller K, Wu H, Zhao S, Jin P, Dalton S
    Stem Cell Reports, 2013;1(6):532-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  378. Production of hepatocyte-like cells from human pluripotent stem cells.
    Authors: Hannan, Nicholas, Segeritz, Charis-P, Touboul, Thomas, Vallier, Ludovic
    Nat Protoc, 2013;8(2):430-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  379. Long-term self-renewal of human ES/iPS-derived hepatoblast-like cells on human laminin 111-coated dishes.
    Authors: Takayama K, Nagamoto Y, Mimura N, Tashiro K, Sakurai F, Tachibana M, Hayakawa T, Kawabata K, Mizuguchi H
    Stem Cell Reports, 2013;1(4):322-35.
  380. MicroRNA-181a suppresses mouse granulosa cell proliferation by targeting activin receptor IIA.
    Authors: Zhang Q, Sun H, Jiang Y, Ding L, Wu S, Fang T, Yan G, Hu Y
    PLoS ONE, 2013;8(3):e59667.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  381. The endothelial cell line bEnd.3 maintains human pluripotent stem cells.
    Authors: Joubin, Katherin, Richardson, Amelia, Novoa, Natalia, Tu, Edmund, Tomishima, Mark J
    Stem Cells Dev, 2012;21(12):2312-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  382. FGF signaling via MAPK is required early and improves Activin A-induced definitive endoderm formation from human embryonic stem cells.
    Authors: Sui L, Mfopou J, Geens M, Sermon K, Bouwens L
    Biochem Biophys Res Commun, 2012;426(3):380-5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  383. APELIN promotes hematopoiesis from human embryonic stem cells.
    Blood, 2012;119(26):6243-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  384. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme.
    Authors: Sneddon, Julie B, Borowiak, Malgorza, Melton, Douglas
    Nature, 2012;491(7426):765-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  385. Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15.
    Authors: Mottershead D, Ritter L, Gilchrist R
    Mol Hum Reprod, 2012;18(3):121-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  386. Cellular basis of tissue regeneration by omentum.
    Authors: Shah S, Lowery E, Braun RK
    PLoS ONE, 2012;7(6):e38368.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  387. Generation of glucose-responsive, insulin-producing cells from human umbilical cord blood-derived mesenchymal stem cells.
    Authors: Prabakar K, Dominguez-Bendala J, Molano R, Pileggi A, Villate S, Ricordi C, Inverardi L
    Cell Transplant, 2012;21(6):1321-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  388. A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells.
    Authors: Wang P, McKnight K, Wong D, Rodriguez R, Sugiyama T, Gu X, Ghodasara A, Qu K, Chang H, Kim S
    Stem Cells Dev, 2012;21(12):2273-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  389. Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-beta pathway.
    Authors: Bruce D, Macartney T, Yong W, Shou W, Sapkota G
    Cell Signal, 2012;24(11):1999-2006.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  390. Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion.
    Authors: Pereira P, Dobreva M, Maas E, Cornelis F, Moya I, Umans L, Verfaillie C, Camus A, de Sousa Lopes S, Huylebroeck D, Zwijsen A
    Development, 2012;139(18):3343-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  391. Differentiation and transplantation of functional pancreatic beta cells generated from induced pluripotent stem cells derived from a type 1 diabetes mouse model.
    Authors: Jeon, Kilsoo, Lim, Hyejin, Kim, Jung-Hyu, Thuan, Nguyen V, Park, Seung Hw, Lim, Yu-Mi, Choi, Hye-Yeon, Lee, Eung-Ryo, Kim, Jin-Hoi, Lee, Myung-Sh, Cho, Ssang-Go
    Stem Cells Dev, 2012;21(14):2642-55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  392. Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals.
    Authors: Zhang Q, Jiang J, Han P, Yuan Q, Zhang J, Zhang X, Xu Y, Cao H, Meng Q, Chen L, Tian T, Wang X, Li P, Hescheler J, Ji G, Ma Y
    Cell Res., 2011;21(4):579-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  393. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro.
    Authors: Spence JR, Mayhew CN, Rankin SA
    Nature, 2011;470(7332):105-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  394. Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells.
    Authors: Tsai SY, Bouwman BA, Ang YS, Kim SJ, Lee DF, Lemischka IR, Rendl M
    Stem Cells, 2011;29(6):964-71.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  395. Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth.
    Authors: Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV
    J. Biol. Chem., 2011;286(34):30034-46.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Surface Plasmon Resonance
  396. Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells.
    Authors: Roelandt P, Pauwelyn KA, Sancho-Bru P
    PLoS ONE, 2010;5(8):e12101.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  397. BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) reveals the involvement of the transforming growth factor-beta family in pain modulation.
    Authors: Tramullas M, Lantero A, Diaz A, Morchon N, Merino D, Villar A, Buscher D, Merino R, Hurle JM, Izpisua-Belmonte JC, Hurle MA
    J. Neurosci., 2010;30(4):1502-11.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  398. A defined glycosaminoglycan-binding substratum for human pluripotent stem cells.
    Authors: Klim JR, Li L, Wrighton PJ
    Nat. Methods, 2010;7(12):989-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  399. Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm.
    Authors: Chayosumrit M, Tuch B, Sidhu K
    Biomaterials, 2010;31(3):505-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  400. SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.
    Authors: Chng Z, Teo A, Pedersen RA, Vallier L
    Cell Stem Cell, 2010;6(1):59-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  401. The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers.
    Authors: Emre N, Vidal JG, Elia J
    PLoS ONE, 2010;5(8):e12148.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  402. Scaffold-free human cardiac tissue patch created from embryonic stem cells.
    Authors: Stevens KR, Pabon L, Muskheli V
    Tissue Eng Part A, 2009;15(6):1211-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  403. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells.
    Authors: Borowiak M, Maehr R, Chen S, Chen AE, Tang W, Fox JL, Schreiber SL, Melton DA
    Cell Stem Cell, 2009;4(4):348-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  404. A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells.
    Authors: Hansson M, Olesen DR, Peterslund JM, Engberg N, Kahn M, Winzi M, Klein T, Maddox-Hyttel P, Serup P
    Dev. Biol., 2009;330(2):286-304.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  405. Differential expression and functional characterization of luteinizing hormone receptor splice variants in human luteal cells: implications for luteolysis.
    Authors: Dickinson RE, Stewart AJ, Myers M, Millar RP, Duncan WC
    Endocrinology, 2009;150(6):2873-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  406. Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.
    Authors: Bernardo AS, Cho CH, Mason S, Docherty HM, Pedersen RA, Vallier L, Docherty K
    Stem Cells, 2009;27(2):341-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  407. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
    Authors: Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L
    Cell Stem Cell, 2008;2(6):602-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  408. BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling.
    Authors: Jeanpierre S, Nicolini FE, Kaniewski B, Dumontet C, Rimokh R, Puisieux A, Maguer-Satta V
    Blood, 2008;112(8):3154-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  409. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population.
    Authors: Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM
    Nature, 2008;453(7194):524-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  410. Combinatorial signals of activin/nodal and bone morphogenic protein regulate the early lineage segregation of human embryonic stem cells.
    Authors: Wu Z, Zhang W, Chen G, Cheng L, Liao J, Jia N, Gao Y, Dai H, Yuan J, Cheng L, Xiao L
    J. Biol. Chem., 2008;283(36):24991-5002.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  411. Guided differentiation of embryonic stem cells into Pdx1-expressing regional-specific definitive endoderm.
    Authors: Shiraki N, Yoshida T, Araki K, Umezawa A, Higuchi Y, Goto H, Kume K, Kume S
    Stem Cells, 2008;26(4):874-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  412. Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo.
    Authors: Oki S, Hashimoto R, Okui Y, Shen MM, Mekada E, Otani H, Saijoh Y, Hamada H
    Development, 2007;134(21):3893-904.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  413. Conditional gene expression in human embryonic stem cells.
    Authors: Vallier L, Alexander M, Pedersen R
    Stem Cells, 2007;25(6):1490-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  414. Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
    Authors: Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S
    Cell, 2007;131(5):861-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  415. Stem cells derived from human fetal membranes display multilineage differentiation potential.
    Authors: Ilancheran S, Michalska A, Peh G, Wallace EM, Pera M, Manuelpillai U
    Biol. Reprod., 2007;77(3):577-88.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  416. Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed.
    Authors: McLean AB, D&amp;amp;apos;Amour KA, Jones KL, Krishnamoorthy M, Kulik MJ, Reynolds DM, Sheppard AM, Liu H, Xu Y, Baetge EE, Dalton S
    Stem Cells, 2007;25(1):29-38.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  417. The neuroprotective effect of Activin A and B: implication for neurodegenerative diseases.
    Authors: Kupershmidt L, Amit T, Bar-Am O, Youdim MB, Blumenfeld Z
    J. Neurochem., 2007;103(3):962-71.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  418. Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling.
    Authors: Wang L, Schulz TC, Sherrer ES, Dauphin DS, Shin S, Nelson AM, Ware CB, Zhan M, Song CZ, Chen X, Brimble SN, McLean A, Galeano MJ, Uhl EW, D'Amour KA, Chesnut JD, Rao MS, Blau CA, Robins AJ
    Blood, 2007;110(12):4111-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  419. Effect of insulin-like growth factor-binding protein 7 on steroidogenesis in granulosa cells derived from equine chorionic gonadotropin-primed immature rat ovaries.
    Authors: Tamura K, Matsushita M, Endo A, Kutsukake M, Kogo H
    Biol. Reprod., 2007;77(3):485-91.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  420. Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB.
    Authors: Alexander S, Watt F, Sawaji Y, Hermansson M, Saklatvala J
    Arthritis Rheum., 2007;56(11):3715-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  421. Predicting evolutionary patterns of mammalian teeth from development.
    Authors: Kavanagh KD, Evans AR, Jernvall J
    Nature, 2007;449(7161):427-32.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  422. Lrp6 is required for convergent extension during Xenopus gastrulation.
    Authors: Tahinci E, Thorne CA, Franklin JL, Salic A, Christian KM, Lee LA, Coffey RJ, Lee E
    Development, 2007;134(22):4095-106.
    Species: Xenopus
    Sample Types: Whole Tissue
    Applications: Bioassay
  423. Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
    Authors: Sherwood RI, Jitianu C, Cleaver O, Shaywitz DA, Lamenzo JO, Chen AE, Golub TR, Melton DA
    Dev. Biol., 2007;304(2):541-55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  424. The activin A-follistatin system: potent regulator of human extracellular matrix mineralization.
    Authors: Eijken M, Swagemakers S, Koedam M, Steenbergen C, Derkx P, Uitterlinden AG, van der Spek PJ, Visser JA, de Jong FH, Pols HA, van Leeuwen JP
    FASEB J., 2007;21(11):2949-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  425. New cell lines from mouse epiblast share defining features with human embryonic stem cells.
    Authors: Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD
    Nature, 2007;448(7150):196-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  426. Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cells.
    Authors: Cho YM, Lim JM, Yoo DH, Kim JH, Chung SS, Park SG, Kim TH, Oh SK, Choi YM, Moon SY, Park KS, Lee HK
    Biochem. Biophys. Res. Commun., 2007;366(1):129-34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  427. A large-scale proteomic analysis of human embryonic stem cells.
    Authors: Schulz TC, Swistowska AM, Liu Y
    BMC Genomics, 2007;8(0):478.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  428. Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells.
    Authors: Kurita R, Sasaki E, Yokoo T, Hiroyama T, Takasugi K, Imoto H, Izawa K, Dong Y, Hashiguchi T, Soda Y, Maeda T, Suehiro Y, Tanioka Y, Nakazaki Y, Tani K
    Stem Cells, 2006;24(9):2014-22.
    Species: Primate - Callitrix jacchus (Common Marmoset)
    Sample Types: Whole Cells
    Applications: Bioassay
  429. Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions.
    Authors: Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, Ding S
    Proc. Natl. Acad. Sci. U.S.A., 2006;103(18):6907-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  430. Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct.
    Authors: Maeshima A, Vaughn DA, Choi Y, Nigam SK
    Dev. Biol., 2006;295(2):473-85.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Bioassay
  431. The role of the activin system in keloid pathogenesis.
    Authors: Mukhopadhyay A, Chan SY, Lim IJ, Phillips DJ, Phan TT
    Am. J. Physiol., Cell Physiol., 2006;292(4):C1331-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  432. Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal.
    Authors: Greber B, Lehrach H, Adjaye J
    Stem Cells, 2006;25(2):455-64.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  433. The activin-follistatin system and in vitro early follicle development in goats.
    Authors: Silva JR, Tharasanit T, Taverne MA, van der Weijden GC, Santos RR, Figueiredo JR, van den Hurk R
    J. Endocrinol., 2006;189(1):113-25.
    Species: Goat
    Sample Types: Whole Tissue
    Applications: Bioassay
  434. Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer.
    Authors: Ng RK, Gurdon JB
    Proc. Natl. Acad. Sci. U.S.A., 2005;102(6):1957-62.
    Species: Xenopus
    Sample Types: Whole Cells
    Applications: Bioassay
  435. Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts.
    Authors: Tardif G, Hum D, Pelletier JP, Boileau C, Ranger P, Martel-Pelletier J
    Arthritis Rheum., 2004;50(8):2521-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  436. Immunoneutralization of growth differentiation factor 9 reveals it partially accounts for mouse oocyte mitogenic activity.
    Authors: Gilchrist RB, Ritter LJ, Cranfield M, Jeffery LA, Amato F, Scott SJ, Myllymaa S, Kaivo-Oja N, Lankinen H, Mottershead DG, Groome NP, Ritvos O
    Biol. Reprod., 2004;71(3):732-9.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  437. hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation.
    Authors: Oren A, Toporik A, Biton S, Almogy N, Eshel D, Bernstein J, Savitsky K, Rotman G
    Gene, 2004;331(0):17-31.
    Species: Human
    Sample Types:
    Applications: Bioassay
  438. Paracrine regulation of FSH by follistatin in folliculostellate cell-enriched primate pituitary cell cultures.
    Authors: Kawakami S, 2019, Fujii Y, Okada Y, Winters SJ
    101203, 2002;143(6):2250-8.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  439. Nuclear exclusion of Smad2 is a mechanism leading to loss of competence.
    Authors: Grimm OH, Gurdon JB
    Nat. Cell Biol., 2002;4(7):519-22.
    Species: Xenopus
    Sample Types: Whole Cells
    Applications: Bioassay
  440. Asynchronous mixing of kidney progenitor cells potentiates nephrogenesis in organoids.
    Authors: Kumar Gupta A, Sarkar P, Wertheim J, Pan X, Carroll T, Oxburgh L
    Commun Biol, 0;3(1):231.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  441. Human Pluripotent Stem Cell-Derived Kidney Model for Nephrotoxicity Studies.
    Authors: Bajaj P, Rodrigues A, Steppan C, Engle S, Mathialagan S, Schroeter T
    Drug Metab Dispos, 0;46(11):1703-1711.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. Can Recombinant Human/Mouse/Rat Activin A Protein (Catalog # 338-AC or 338-AC/CF) be reconstituted in PBS or water?

    • Recombinant human Activin A needs to be reconstituted to 100 - 500 μg/mL in sterile 4 mM HCl. This protein is hydrophobic by nature, and requires reconstitution in acidic buffer for optimal recovery. Stability testing has been evaluated on the protein with these reconstitution conditions; we can guarantee performance under these reconstitution conditions. When the protein is diluted with the cell culture media or buffers to the working concentration, the concentration of the acid should be buffered or negligible.

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Animal Component Free Recombinant Proteins

Reviews for Recombinant Human/Mouse/Rat Activin A Protein

Average Rating: 4.7 (Based on 12 Reviews)

5 Star
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Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 07/09/2020
Application: SDS-PAGE Control

Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 02/10/2019
Application: Stem/Immune cell maintenance or differentiation

induction of mesoderm for differentiation of primordial germ cell like cells from human pluripotent stem cells (Fig. Nanos3 expression in human primordial germ cell like cells)


Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 08/20/2018
Application: In vitro bioactivity in cell culture

Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 12/21/2017
Application: In vitro bioactivity in cell culture

Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 12/01/2017
Application: Stem/Immune cell maintenance or differentiation
Reason for Rating: Upon titration with BMP-4, we found the ideal concentrations for producing cardiomyocytes positive for both cTnT and MLC-2V which we then use in drug toxicity and electrophysiological assays.

Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 05/17/2017
Application: In vitro bioactivity in cell culture

Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 04/21/2017
Application:

Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 12/06/2016
Application: Stem/Immune cell maintenance or differentiation

Routinely used in our lab for growth-factor guided differentiation protocol for cardiomyocyte differentiation from human pluripotent stem cells


Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 12/06/2016
Application: Stem/Immune cell maintenance or differentiation

To differentiate human induced pluripotent stem cells (derived from patients) towards hepatocytes, to differentiate mouse embryonic stem cells into epiblast like stem cells,, and to culture mouse epiblast like stem cells.


Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 12/06/2016
Application: Stem/Immune cell maintenance or differentiation

We are using Activin A from R&D for generating definitive endoderm from human pluripotent stem cells.


Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 01/19/2016
Application: Stem/Immune cell maintenance or differentiation
Reason for Rating: This reagent worked perfectly for the maintenance of trophoblast stem cells.

Trophoblast stem cells are maintained in the presence of growth factors and other substances such as Activin (cat# 338-AC/CF). When the substances are removed, the cells differentiate into giant cells (see image).


Recombinant Human/Mouse/Rat Activin A Protein
By Anonymous on 01/13/2016
Application: We used it for cardic differentiation and it works fine.