Recombinant Human VEGF 165 Protein, CF

(224 citations)   
  • Purity
    >97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Endotoxin Level
    <0.01 EU per 1 μg of the protein by the LAL method.
  • Activity
    Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. Conn, G. et al. (1990) Proc. Natl. Acad. Sci. USA 87:1323. The ED50 for this effect is 1-6 ng/mL.
    The specific activity of recombinant human VEGF165 is approximately 1.7 x 103 U/μg, which is calibrated against recombinant human VEGF165 WHO Standard (NIBSC code: 02/286).
  • Source
    Spodoptera frugiperda, Sf 21 (baculovirus)-derived Ala27-Arg191
  • Accession #
  • N-terminal Sequence
    Analysis
    Ala27
  • Structure / Form
    Disulfide-linked homodimer
  • Predicted Molecular Mass
    19.2 kDa (monomer)
  • SDS-PAGE
    20-22 kDa, reducing conditions
    39-42 kDa, non-reducing conditions
Carrier Free
What does CF mean?
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
What formulation is right for me?
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
293-VE/CF
 
293-VE
Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with trehalose.
Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS. Alternatively, reconstitute at 500 μg/mL in sterile 4 mM HCl.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. Alternatively, reconstitute at 500 μg/mL in sterile 4 mM HCl containing 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Data Images
Recombinant Human VEGF165 (Catalog # 293-VE/CF) stimulates proliferation in HUVEC human umbilical vein endothelial cells. The ED50 is 1-6 ng/mL.
1 μg/lane of Recombinant Human VEGF165 was resolved by SDS-PAGE with silver staining, under reducing (R) and non-reducing (NR) conditions, showing major bands at 20-22 kDa and 39-42 kDa, respectively. Multiple bands in gel are due to glycosylation.
Background: VEGF

Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult (1-3). It is a member of the PDGF family that is characterized by the presence of eight conserved cysteine residues and a cystine knot structure (4). Humans express alternately spliced isoforms of 121, 145, 165, 183, 189, and 206 amino acids (aa) in length (4). VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189 (3, 4). Isoforms other than VEGF121 contain basic heparin-binding regions and are not freely diffusible (4). Human VEGF165 shares 88% aa sequence identity with corresponding regions of mouse and rat, 96% with porcine, 95% with canine, and 93% with feline, equine and bovine VEGF, respectively. VEGF binds the type I transmembrane receptor tyrosine kinases VEGF R1 (also called Flt-1) and VEGF R2 (Flk-1/KDR) on endothelial cells (4). Although VEGF affinity is highest for binding to VEGF R1, VEGF R2 appears to be the primary mediator of VEGF angiogenic activity (3, 4). VEGF165 binds the semaphorin receptor, Neuropilin-1 and promotes complex formation with VEGF R2 (5). VEGF is required during embryogenesis to regulate the proliferation, migration, and survival of endothelial cells (3, 4). In adults, VEGF functions mainly in wound healing and the female reproductive cycle (3). Pathologically, it is involved in tumor angiogenesis and vascular leakage (6, 7). Circulating VEGF levels correlate with disease activity in autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (8). VEGF is induced by hypoxia and cytokines such as IL-1, IL-6, IL-8, oncostatin M and TNF-alpha (3, 4, 9).

  • References:
    1. Leung, D.W. et al. (1989) Science 246:1306. 
    2. Keck, P.J. et al. (1989) Science 246:1309. 
    3. Byrne, A.M. et al. (2005) J. Cell. Mol. Med. 9:777. 
    4. Robinson, C.J. and S.E. Stringer (2001) J. Cell. Sci. 114:853.
    5. Pan, Q. et al. (2007) J. Biol. Chem. 282:24049.
    6. Weis, S.M. and D.A. Cheresh (2005) Nature 437:497.
    7. Thurston, G. (2002) J. Anat. 200:575.
    8. Carvalho, J.F. et al. (2007) J. Clin. Immunol. 27:246.
    9. Angelo, L.S. and R. Kurzrock (2007) Clin. Cancer Res. 13:2825.
  • Long Name:
    Vascular Endothelial Growth Factor
  • Entrez Gene IDs:
    7422 (Human); 22339 (Mouse); 83785 (Rat); 281572 (Bovine); 403802 (Canine); 493845 (Feline); 30682 (Zebrafish)
  • Alternate Names:
    MVCD1; VAS; vascular endothelial growth factor A; Vascular permeability factor; Vasculotropin; VEGF; VEGFA; VEGF-A; VEGFMGC70609; VPF; VPFvascular endothelial growth factor
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

224 Citations: Showing 1 - 10
Filter your results:

Species
Applications
Sample Type
  1. Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis
    Authors: Z Liu, S Yan, J Wang, Y Xu, Y Wang, S Zhang, X Xu, Q Yang, X Zeng, Y Zhou, X Gu, S Lu, Z Fu, DJ Fulton, NL Weintraub, RB Caldwell, W Zhang, C Wu, XL Liu, JF Chen, A Ahmad, I Kaddour-Dj, M Al-Shabraw, Q Li, X Jiang, Y Sun, A Sodhi, L Smith, M Hong, Y Huo
    Nat Commun, 2017;8(1):584.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  2. In smokers, Sonic hedgehog modulates pulmonary endothelial function through vascular endothelial growth factor
    Authors: P Henno, S Grassin-De, E Belle, M Brollo, E Naline, E Sage, P Devillier, D Israël-Bie
    Respir. Res., 2017;18(1):102.
    Species: Human
    Sample Type: Whole Tissue
    Application: Bioassay
  3. Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3
    Authors: H He, AE Kuriyan, CW Su, M Mahabole, Y Zhang, YT Zhu, HW Flynn, JM Parel, SC Tseng
    Sci Rep, 2017;7(0):43736.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  4. Gelatin device for the delivery of growth factors involved in endochondral ossification
    Authors: LA Ahrens, D Vonwil, J Christense, VP Shastri
    PLoS ONE, 2017;12(4):e0175095.
    Species: Chicken
    Sample Type: Egg
    Application: Bioassay
  5. Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis
    Authors: LA Murray, DM Habiel, M Hohmann, A Camelo, H Shang, Y Zhou, AL Coelho, X Peng, M Gulati, B Crestani, MA Sleeman, T Mustelin, MW Moore, C Ryu, AD Osafo-Addo, JA Elias, CG Lee, B Hu, JD Herazo-May, DA Knight, CM Hogaboam, EL Herzog
    JCI Insight, 2017;2(16):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  6. Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
    Authors: JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
    Cell Stem Cell, 2017;21(2):179-194.e4.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  7. PM2.5 exposure decreases viability, migration and angiogenesis in human umbilical vein endothelial cells and human microvascular endothelial cells
    Authors: S Chen, X Wu, J Hu, G Dai, A Rong, G Guo
    Mol Med Rep, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  8. Apatinib, an Inhibitor of Vascular Endothelial Growth Factor Receptor 2, Suppresses Pathologic Ocular Neovascularization in Mice
    Authors: KL Kim, W Suh
    Invest. Ophthalmol. Vis. Sci., 2017;58(9):3592-3599.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  9. Inhibition of Single Routes of Intracellular Signaling is Not Sufficient to Neutralize the Biphasic Disturbance of a Retinal Endothelial Cell Barrier Induced by VEGF-A165
    Authors: HL Deissler, GK Lang, GE Lang
    Cell. Physiol. Biochem., 2017;42(4):1493-1513.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  10. TNF?-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels
    Authors: AE van der Wi, IMC Vogels, CJF van Noorde, I Klaassen, RO Schlingema
    Invest. Ophthalmol. Vis. Sci., 2017;58(9):3496-3505.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  11. Dual targeting of vascular endothelial growth factor and bone morphogenetic protein-9/10 impairs tumor growth through inhibition of angiogenesis
    Authors: Y Akatsu, Y Yoshimatsu, T Tomizawa, K Takahashi, A Katsura, K Miyazono, T Watabe
    Cancer Sci, 2017;108(1):151-155.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  12. Tie1 controls angiopoietin function in vascular remodeling and inflammation
    J Clin Invest, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  13. Macrophages Enhance Migration in Inflammatory Breast Cancer Cells via RhoC GTPase Signaling
    Sci Rep, 2016;6(0):39190.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  14. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance
    Authors: C Jang, SF Oh, S Wada, GC Rowe, L Liu, MC Chan, J Rhee, A Hoshino, B Kim, A Ibrahim, LG Baca, E Kim, CC Ghosh, SM Parikh, A Jiang, Q Chu, DE Forman, SH Lecker, S Krishnaiah, JD Rabinowitz, AM Weljie, JA Baur, DL Kasper, Z Arany
    Nat Med, 2016;22(4):421-6.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  15. Miniaturizing VEGF: Peptides mimicking the discontinuous VEGF receptor-binding site modulate the angiogenic response
    Sci Rep, 2016;6(0):31295.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  16. Angiogenic Effects of Collagen/Mesoporous Nanoparticle Composite Scaffold Delivering VEGF165
    Biomed Res Int, 2016;2016(0):9676934.
    Species: Rat
    Sample Type: In Vivo
    Application: In Vivo
  17. CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy
    Invest Ophthalmol Vis Sci, 2016;57(10):4017-26.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  18. MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation
    Authors: I Papangeli, J Kim, I Maier, S Park, A Lee, Y Kang, K Tanaka, OF Khan, H Ju, Y Kojima, K Red-Horse, DG Anderson, AF Siekmann, HJ Chun
    Nat Commun, 2016;7(0):11268.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  19. Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer
    Oncotarget, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  20. The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization
    Nat Commun, 2016;7(0):13517.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  21. Proline-rich tyrosine kinase 2 via enhancing signal transducer and activator of transcription 3-dependent cJun expression mediates retinal neovascularization
    Sci Rep, 2016;6(0):26480.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  22. Neuropilin-1 is a receptor for extracellular miRNA and AGO2/miRNA complexes and mediates the internalization of miRNAs that modulate cell function
    Authors: GJ Prud'homme, Y Glinka, Z Lichner, GM Yousef
    Oncotarget, 2016;7(42):68057-68071.
    Species: Human
    Sample Type: RNA
    Application: Bioassay
  23. The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain
    Neurobiol Dis, 2016;96(0):186-200.
    Species: Rat
    Sample Type: In Vivo
    Application: In Vivo
  24. Mesenchymal Stem Cells Reshape and Provoke Proliferation of Articular Chondrocytes by Paracrine Secretion
    Sci Rep, 2016;6(0):32705.
    Species: Rabbit
    Sample Type: Whole Cells
    Application: Bioassay
  25. Insulin-like growth factor 1 (IGF-1) stabilizes nascent blood vessels.
    Authors: Jacobo S, Kazlauskas A
    J Biol Chem, 2015;290(10):6349-60.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  26. Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.
    Authors: Rama N, Dubrac A, Mathivet T, Ni Charthaigh R, Genet G, Cristofaro B, Pibouin-Fragner L, Ma L, Eichmann A, Chedotal A
    Nat Med, 2015;21(5):483-91.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  27. IL-25 induces airways angiogenesis and expression of multiple angiogenic factors in a murine asthma model.
    Authors: Yao, Xiujuan, Wang, Wei, Li, Yan, Huang, Ping, Zhang, Qian, Wang, Jingjing, Wang, Wen, Lv, Zhe, An, Yunqing, Qin, Jianguo, Corrigan, Chris J, Huang, Kewu, Sun, Yongchan, Ying, Sun
    Respir Res, 2015;16(0):39.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  28. The effect of vascular endothelial growth factor on osteoclastogenesis in rheumatoid arthritis.
    Authors: Kim H, Kim K, Kim B, Cho M, Lee S
    PLoS ONE, 2015;10(4):e0124909.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  29. GSK3beta inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells.
    Authors: Kitajima K, Nakajima M, Kanokoda M, Kyba M, Dandapat A, Tolar J, Saito M, Toyoda M, Umezawa A, Hara T
    Exp Hematol, 2015;44(1):68-74.e10.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  30. BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth.
    Authors: Wang T, Xiao M, Ge Y, Krepler C, Belser E, Lopez-Coral A, Xu X, Zhang G, Azuma R, Liu Q, Liu R, Li L, Amaravadi R, Xu W, Karakousis G, Gangadhar T, Schuchter L, Lieu M, Khare S, Halloran M, Herlyn M, Kaufman R
    Clin Cancer Res, 2015;21(7):1652-64.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  31. R-Ras protein inhibits autophosphorylation of vascular endothelial growth factor receptor 2 in endothelial cells and suppresses receptor activation in tumor vasculature.
    Authors: Sawada J, Li F, Komatsu M
    J Biol Chem, 2015;290(13):8133-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  32. Ecto-5'-nucleotidase/CD73 enhances endothelial barrier function and sprouting in blood but not lymphatic vasculature.
    Authors: Yegutkin G, Auvinen K, Rantakari P, Hollmen M, Karikoski M, Grenman R, Elima K, Jalkanen S, Salmi M
    Eur J Immunol, 2015;45(2):562-73.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  33. Inhibition of IGF-1-Mediated Cellular Migration and Invasion by Migracin A in Ovarian Clear Cell Carcinoma Cells.
    Authors: Ukaji T, Lin Y, Banno K, Okada S, Umezawa K
    PLoS ONE, 2015;10(9):e0137663.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  34. VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2.
    Authors: Zhao D, Pan C, Sun J, Gilbert C, Drews-Elger K, Azzam D, Picon-Ruiz M, Kim M, Ullmer W, El-Ashry D, Creighton C, Slingerland J
    Oncogene, 2015;34(24):3107-19.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  35. Synergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity.
    Authors: Teran M, Nugent M
    J Biol Chem, 2015;290(26):16451-62.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  36. The bipartite rac1 Guanine nucleotide exchange factor engulfment and cell motility 1/dedicator of cytokinesis 180 (elmo1/dock180) protects endothelial cells from apoptosis in blood vessel development.
    Authors: Schaker K, Bartsch S, Patry C, Stoll S, Hillebrands J, Wieland T, Kroll J
    J Biol Chem, 2015;290(10):6408-18.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  37. JSI-124 suppresses invasion and angiogenesis of glioblastoma cells in vitro.
    Authors: Yuan G, Yan S, Xue H, Zhang P, Sun J, Li G
    PLoS ONE, 2015;10(3):e0118894.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  38. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling.
    Authors: Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, Segarra M, Eberhart C, Acker-Palmer A, Tosato G
    Nat Commun, 2015;6(0):6576.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  39. Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P).
    Authors: Williams P, Stilhano R, To V, Tran L, Wong K, Silva E
    PLoS ONE, 2015;10(4):e0123437.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  40. The proangiogenic effect of iroquois homeobox transcription factor Irx3 in human microvascular endothelial cells.
    Authors: Scarlett K, Pattabiraman V, Barnett P, Liu D, Anderson L
    J Biol Chem, 2015;290(10):6303-15.
  41. Improved hematopoietic differentiation efficiency of gene-corrected beta-thalassemia induced pluripotent stem cells by CRISPR/Cas9 system.
    Authors: Song B, Fan Y, He W, Zhu D, Niu X, Wang D, Ou Z, Luo M, Sun X
    Stem Cells Dev, 2015;24(9):1053-65.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  42. Simultaneous targeting of two ligand-binding sites on VEGFR2 using biparatopic Affibody molecules results in dramatically improved affinity.
    Authors: Fleetwood F, Klint S, Hanze M, Gunneriusson E, Frejd F, Stahl S, Lofblom J
    Sci Rep, 2014;4(0):7518.
  43. Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells.
    Authors: Orlova, Valeria, van den Hil, Francijn, Petrus-Reurer, Sandra, Drabsch, Yvette, Ten Dijke, Peter, Mummery, Christin
    Nat Protoc, 2014;9(6):1514-31.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  44. Effects of sFlt-1 and alpha 2-macroglobulin on vascular endothelial growth factor-induced endothelin-1 upregulation in human microvascular endothelial cells.
    Authors: Yi K, Jung S, Cho G, Seol H, Hong S, Oh M, Kim H
    Placenta, 2014;35(1):64-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  45. miR-27a regulates endothelial differentiation of breast cancer stem like cells.
    Authors: Tang, W, Yu, F, Yao, H, Cui, X, Jiao, Y, Lin, L, Chen, J, Yin, D, Song, E, Liu, Q
    Oncogene, 2014;33(20):2629-38.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  46. Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis.
    Authors: Morishima, Tatsuya, Watanabe, Ken-ichi, Niwa, Akira, Hirai, Hideyo, Saida, Satoshi, Tanaka, Takayuki, Kato, Itaru, Umeda, Katsutsu, Hiramatsu, Hidefumi, Saito, Megumu K, Matsubara, Kousaku, Adachi, Souichi, Kobayashi, Masao, Nakahata, Tatsutos, Heike, Toshio
    Haematologica, 2014;99(1):19-27.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  47. Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential.
    Authors: Cubbon R, Yuldasheva N, Viswambharan H, Mercer B, Baliga V, Stephen S, Askham J, Sukumar P, Skromna A, Mughal R, Walker A, Bruns A, Bailey M, Galloway S, Imrie H, Gage M, Rakobowchuk M, Li J, Porter K, Ponnambalam S, Wheatcroft S, Beech D, Kearney M
    Stem Cells, 2014;32(10):2714-23.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  48. Conformational remodeling of the fibronectin matrix selectively regulates VEGF signaling.
    Authors: Ambesi A, McKeown-Longo P
    J Cell Sci, 2014;127(0):3805-16.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  49. Gas6 stimulates angiogenesis of human retinal endothelial cells and of zebrafish embryos via ERK1/2 signaling.
    Authors: Kim, Young So, Jung, Seung-Hy, Jung, Dong Ho, Choi, So-Jin, Lee, Yu-Ri, Kim, Jin Sook
    PLoS ONE, 2014;9(1):e83901.
    Species: Zebrafish
    Sample Type: Whole Organism
    Application: In Vivo
  50. Angiogenic sprouting is regulated by endothelial cell expression of Slug.
    Authors: Welch-Reardon K, Ehsan S, Wang K, Wu N, Newman A, Romero-Lopez M, Fong A, George S, Edwards R, Hughes C
    J Cell Sci, 2014;127(0):2017-28.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  51. Glutathione adducts on sarcoplasmic/endoplasmic reticulum Ca2+ ATPase Cys-674 regulate endothelial cell calcium stores and angiogenic function as well as promote ischemic blood flow recovery.
    Authors: Thompson M, Mei Y, Weisbrod R, Silver M, Shukla P, Bolotina V, Cohen R, Tong X
    J Biol Chem, 2014;289(29):19907-16.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  52. Intraocular pharmacokinetics of ranibizumab in vitrectomized versus nonvitrectomized eyes.
    Authors: Ahn S, Ahn J, Park S, Kim H, Hwang D, Park J, Park J, Chung J, Park K, Woo S
    Invest Ophthalmol Vis Sci, 2014;55(1):567-73.
    Species: Human
    Sample Type: Whole Tissue
    Application: Bioassay
  53. Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling.
    Authors: Nakamura I, Zakharia K, Banini B, Mikhail D, Kim T, Yang J, Moser C, Shaleh H, Thornburgh S, Walters I, Roberts L
    PLoS ONE, 2014;9(4):e92273.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  54. Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.
    Authors: Seano G, Chiaverina G, Gagliardi P, di Blasio L, Puliafito A, Bouvard C, Sessa R, Tarone G, Sorokin L, Helley D, Jain R, Serini G, Bussolino F, Primo L
    Nat Cell Biol, 2014;16(10):931-41, 1-8.
    Species: Human
    Sample Type: Whole Cells
    Application: cell culture
  55. Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.
    Authors: Adini, Irit, Ghosh, Kaustabh, Adini, Avner, Chi, Zai-Long, Yoshimura, Takeru, Benny, Ofra, Connor, Kip M, Rogers, Michael, Bazinet, Lauren, Birsner, Amy E, Bielenberg, Diane R, D'Amato, Robert J
    J Clin Invest, 2014;124(1):425-36.
    Species: Human
    Sample Type: Whole Cells
    Application: cell culture
  56. An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors.
    Authors: Falcon B, Swearingen M, Gough W, Lee L, Foreman R, Uhlik M, Hanson J, Lee J, McClure D, Chintharlapalli S
    PLoS ONE, 2014;9(9):e106901.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  57. Sox7 is regulated by ETV2 during cardiovascular development.
    Authors: Behrens, Ann N, Zierold, Claudia, Shi, Xiaozhon, Ren, Yi, Koyano-Nakagawa, Naoko, Garry, Daniel J, Martin, Cindy M
    Stem Cells Dev, 2014;23(17):2004-13.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  58. Peroxisome proliferator-activated receptor gamma ligands inhibit VEGF-mediated vasculogenic mimicry of prostate cancer through the AKT signaling pathway.
    Authors: Qin L, Ren Y, Chen A, Guo F, Xu F, Gong C, Cheng P, Du Y, Liao H
    Mol Med Rep, 2014;10(1):276-82.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  59. The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development.
    Authors: Miura S, Kondo J, Takimoto A, Sano-Takai H, Guo L, Shukunami C, Tanaka H, Hiraki Y
    PLoS ONE, 2014;9(4):e94239.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  60. Memo has a novel role in S1P signaling and is [corrected] crucial for vascular development.
    Authors: Kondo, Shunya, Bottos, Alessia, Allegood, Jeremy C, Masson, Regis, Maurer, Francisc, Genoud, Christel, Kaeser, Patrick, Huwiler, Andrea, Murakami, Masato, Spiegel, Sarah, Hynes, Nancy E
    PLoS ONE, 2014;9(4):e94114.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  61. Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye.
    Authors: Michael, Iacovos, Westenskow, Peter D, Hacibekiroglu, Sabiha, Greenwald, Alissa C, Ballios, Brian G, Kurihara, Toshihid, Li, Zhijie, Warren, Carmen M, Zhang, Puzheng, Aguilar, Edith, Donaldson, Laura, Marchetti, Valentin, Baba, Takeshi, Hussein, Samer M, Sung, Hoon-Ki, Iruela-Arispe, M Luisa, Rini, James M, van der Kooy, Derek, Friedlander, Martin, Nagy, Andras
    EMBO Mol Med, 2014;6(5):604-23.
  62. Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts.
    Authors: Orlova, Valeria, Drabsch, Yvette, Freund, Christia, Petrus-Reurer, Sandra, van den Hil, Francijn, Muenthaisong, Suchitra, Dijke, Peter Te, Mummery, Christin
    Arterioscler Thromb Vasc Biol, 2014;34(1):177-86.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  63. Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas.
    Authors: Shahrabi-Farahani, Shokoufe, Wang, Lili, Zwaans, Bernadet, Santana, Jeans M, Shimizu, Akio, Takashima, Seiji, Kreuter, Michael, Coultas, Leigh, D'Amore, Patricia, Arbeit, Jeffrey, Akslen, Lars A, Bielenberg, Diane R
    Lab Invest, 2014;94(7):752-65.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  64. Heparin binding VEGF isoforms attenuate hyperoxic embryonic lung growth retardation via a FLK1-neuropilin-1-PKC dependent pathway.
    Authors: Esquibies A, Karihaloo A, Quaggin S, Bazzy-Asaad A, Cantley L
    Respir Res, 2014;15(0):32.
    Species: Mouse
    Sample Type: Whole Tissue
    Application: Bioassay
  65. Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
    Authors: Fan J, Ponferrada V, Sato T, Vemaraju S, Fruttiger M, Gerhardt H, Ferrara N, Lang R
    Development, 2014;141(2):448-59.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  66. Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability.
    Authors: Hendel, Alon, Hsu, Ivy, Granville, David J
    Lab Invest, 2014;94(7):716-25.
    Species: Human
    Sample Type: Protein
    Application: Bioassay
  67. Dll4-containing exosomes induce capillary sprout retraction in a 3D microenvironment.
    Authors: Sharghi-Namini S, Tan E, Ong L, Ge R, Asada H
    Sci Rep, 2014;4(0):4031.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  68. LF-15 & T7, synthetic peptides derived from tumstatin, attenuate aspects of airway remodelling in a murine model of chronic OVA-induced allergic airway disease.
    Authors: Grafton K, Moir L, Black J, Hansbro N, Hansbro P, Burgess J, Oliver B
    PLoS ONE, 2014;9(1):e85655.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  69. PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells.
    Authors: Lanahan A, Lech D, Dubrac A, Zhang J, Zhuang Z, Eichmann A, Simons M
    Circulation, 2014;130(11):902-9.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  70. Janus kinase 1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses.
    Authors: Ashino S, Takeda K, Li H, Taylor V, Joetham A, Pine P, Gelfand E
    J Allergy Clin Immunol, 2014;133(4):1162-74.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  71. Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis.
    Authors: Wollin L, Maillet I, Quesniaux V, Holweg A, Ryffel B
    J Pharmacol Exp Ther, 2014;349(2):209-20.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  72. MMP9 processing of HSPB1 regulates tumor progression.
    Authors: Choi, Seo-hyun, Lee, Hae-June, Jin, Yeung Ba, Jang, Junho, Kang, Ga-young, Lee, Minyoung, Kim, Chun-Ho, Kim, Joon, Yoon, Sam S, Lee, Yun-sil, Lee, Yoon-Jin
    PLoS ONE, 2014;9(1):e85509.
  73. Rap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure.
    Authors: Lakshmikanthan S, Zieba B, Ge Z, Momotani K, Zheng X, Lund H, Artamonov M, Maas J, Szabo A, Zhang D, Auchampach J, Mattson D, Somlyo A, Chrzanowska-Wodnicka M
    Arterioscler Thromb Vasc Biol, 2014;34(7):1486-94.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  74. The docking protein FRS2alpha is a critical regulator of VEGF receptors signaling.
    Authors: Chen P, Qin L, Zhuang Z, Tellides G, Lax I, Schlessinger J, Simons M
    Proc Natl Acad Sci U S A, 2014;111(15):5514-9.
  75. HOXC9 regulates formation of parachordal lymphangioplasts and the thoracic duct in zebrafish via stabilin 2.
    Authors: Stoll S, Bartsch S, Kroll J
    PLoS ONE, 2013;8(3):e58311.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  76. Abl family kinases regulate endothelial barrier function in vitro and in mice.
    Authors: Chislock, Elizabet, Pendergast, Ann Mari
    PLoS ONE, 2013;8(12):e85231.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  77. Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin.
    Authors: Tannetta D, Dragovic R, Gardiner C, Redman C, Sargent I
    PLoS ONE, 2013;8(2):e56754.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  78. Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions.
    Authors: Smith A, Bowers S, Stratman A, Davis G
    PLoS ONE, 2013;8(12):e85147.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  79. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis.
    Authors: Zhang G, Panigrahy D, Mahakian L, Yang J, Liu J, Stephen Lee K, Wettersten H, Ulu A, Hu X, Tam S, Hwang S, Ingham E, Kieran M, Weiss R, Ferrara K, Hammock B
    Proc Natl Acad Sci U S A, 2013;110(16):6530-5.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  80. Simple patterned nanofiber scaffolds and its enhanced performance in immunoassay.
    Authors: Wang, Jing, Kang, Qin-shu, Lv, Xiao-gua, Song, Jia, Zhan, Na, Dong, Wei-guo, Huang, Wei-hua
    PLoS ONE, 2013;8(12):e82888.
    Species: Human
    Sample Type: N/A
    Application: micro-immunoassay development
  81. Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations.
    Authors: You C, Sandalcioglu I, Dammann P, Felbor U, Sure U, Zhu Y
    J Cell Mol Med, 2013;17(3):407-18.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  82. Structure-activity relationships of benzbromarone metabolites and derivatives as EYA inhibitory anti-angiogenic agents.
    Authors: Pandey, Ram Nare, Wang, Tim Sen, Tadjuidje, Emmanuel, McDonald, Matthew, Rettie, Allan E, Hegde, Rashmi S
    PLoS ONE, 2013;8(12):e84582.
    Species: Mouse
    Sample Type: Whole Tissue
    Application: Bioassay
  83. Resveratrol attenuates diabetic nephropathy via modulating angiogenesis.
    Authors: Wen, Donghai, Huang, Xinzhong, Zhang, Min, Zhang, Liying, Chen, Jing, Gu, Yong, Hao, Chuan-Mi
    PLoS ONE, 2013;8(12):e82336.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  84. Distinct transcriptional profiles of angioblasts derived from human embryonic stem cells.
    Authors: Song S, Jung W, Kim K, Hong W, Kim H, Lee K, Lee K, Suh W
    Exp Cell Res, 2013;319(8):1136-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  85. Detection of rapalog-mediated therapeutic response in renal cancer xenografts using (6)(4)Cu-bevacizumab immunoPET.
    Authors: Chang A, Sohn R, Lu Z, Arbeit J, Lapi S
    PLoS ONE, 2013;8(0):U821.
    Species: Human
    Sample Type: Antibody
    Application: Bioassay
  86. Monoubiquitination of filamin B regulates vascular endothelial growth factor-mediated trafficking of histone deacetylase 7.
    Authors: Su, Yu-Ting, Gao, Chengzhu, Liu, Yu, Guo, Shuang, Wang, Anthony, Wang, Benlian, Erdjument-Bromage, Hediye, Miyagi, Masaru, Tempst, Paul, Kao, Hung-Yin
    Mol Cell Biol, 2013;33(8):1546-60.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  87. Unraveling a novel transcription factor code determining the human arterial-specific endothelial cell signature.
    Authors: Aranguren X, Agirre X, Beerens M, Coppiello G, Uriz M, Vandersmissen I, Benkheil M, Panadero J, Aguado N, Pascual-Montano A, Segura V, Prosper F, Luttun A
    Blood, 2013;122(24):3982-92.
    Species: Human
    Sample Type: In Vivo
    Application: In Vivo
  88. Detection of VEGF-A(xxx)b isoforms in human tissues.
    Authors: Bates, David O, Mavrou, Athina, Qiu, Yan, Carter, James G, Hamdollah-Zadeh, Maryam, Barratt, Shaney, Gammons, Melissa, Millar, Ann B, Salmon, Andrew H, Oltean, Sebastia, Harper, Steven J
    PLoS ONE, 2013;8(7):e68399.
    Species: N/A
    Sample Type: Recombinant Protein
    Application: WB Ctrl
  89. Semaphorin 6A regulates angiogenesis by modulating VEGF signaling.
    Authors: Segarra, Marta, Ohnuki, Hidetaka, Maric, Dragan, Salvucci, Ombretta, Hou, Xu, Kumar, Anil, Li, Xuri, Tosato, Giovanna
    Blood, 2012;120(19):4104-15.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  90. Sjogren's syndrome pathological neovascularization is regulated by VEGF-A-stimulated TACE-dependent crosstalk between VEGFR2 and NF-kappaB.
    Authors: Sisto M, Lisi S, Lofrumento DD, D'Amore M, Frassanito MA, Ribatti D
    Genes Immun., 2012;13(5):411-20.
    Species: Chicken
    Sample Type: In Ovo
    Application: Bioassay
  91. Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin alphavbeta5-induced secretion of VEGF-A.
    Am. J. Pathol., 2012;181(2):693-705.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  92. Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
    Authors: Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbe C, Caillat-Zucman S
    PLoS Pathog., 2012;8(1):e1002486.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  93. Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting.
    Authors: van Meeteren LA, Thorikay M, Bergqvist S, Pardali E, Stampino CG, Hu-Lowe D, Goumans MJ, ten Dijke P
    J. Biol. Chem., 2012;287(22):18551-61.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  94. Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT.
    Blood, 2012;119(26):6278-87.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  95. ADAMTS5 functions as an anti-angiogenic and anti-tumorigenic protein independent of its proteoglycanase activity.
    Authors: Kumar S, Sharghi-Namini S, Rao N, Ge R
    Am J Pathol, 2012;181(3):1056-68.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  96. The regulatory roles of apoptosis-inducing factor in the formation and regression processes of ocular neovascularization.
    Authors: Hisatomi T, Nakao S, Murakami Y, Noda K, Nakazawa T, Notomi S, Connolly E, She H, Almulki L, Ito Y, Vavvas DG, Ishibashi T, Miller JW
    Am. J. Pathol., 2012;181(1):53-61.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  97. Modulation of endothelial cell migration and angiogenesis: a novel function for the "tandem-repeat" lectin galectin-8.
    Authors: Delgado VM, Nugnes LG, Colombo LL, Troncoso MF, Fernandez MM, Malchiodi EL, Frahm I, Croci DO, Compagno D, Rabinovich GA, Wolfenstein-Todel C, Elola MT
    FASEB J., 2011;25(1):242-54.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  98. Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells.
    Authors: Evans IM, Yamaji M, Britton G, Pellet-Many C, Lockie C, Zachary IC, Frankel P
    Mol. Cell. Biol., 2011;31(6):1174-85.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  99. Increased VEGFR-2 Gene Copy Is Associated with Chemoresistance and Shorter Survival in Patients with Non-Small-Cell Lung Carcinoma Who Receive Adjuvant Chemotherapy.
    Authors: Yang F, Tang X, Riquelme E, Behrens C, Nilsson MB, Giri U, Varella-Garcia M, Byers LA, Lin HY, Wang J, Raso MG, Girard L, Coombes K, Lee JJ, Herbst RS, Minna JD, Heymach JV, Wistuba II
    Cancer Res., 2011;71(16):5512-5521.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  100. Flt-1 regulates vascular endothelial cell migration via a protein tyrosine kinase-7-dependent pathway.
    Authors: Lee HK, Chauhan SK, Kay E
    Blood, 2011;117(21):5762-71.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  101. Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation.
    Authors: Pirotte S, Lamour V, Lambert V, Alvarez Gonzalez ML, Ormenese S, Noel A, Mottet D, Castronovo V, Bellahcene A
    Blood, 2011;117(8):2515-26.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  102. Endorepellin, the angiostatic module of perlecan, interacts with both the alpha2beta1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism.
    Authors: Goyal A, Pal N, Concannon M, Paul M, Doran M, Poluzzi C, Sekiguchi K, Whitelock JM, Neill T, Iozzo RV
    J. Biol. Chem., 2011;286(29):25947-62.
    Species: Human
    Sample Type: Recombinant Protein
    Application: Binding Competition
  103. A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors.
    Authors: Niwa A, Heike T, Umeda K
    PLoS ONE, 2011;6(7):e22261.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  104. Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells.
    Authors: Ball SG, Bayley C, Shuttleworth CA, Kielty CM
    Biochem. J., 2010;427(1):29-40.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  105. Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state.
    Authors: Lanner F, Lee KL, Sohl M, Holmborn K, Yang H, Wilbertz J, Poellinger L, Rossant J, Farnebo F
    Stem Cells, 2010;28(2):191-200.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  106. Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch.
    Authors: Ding W, Knox TR, Tschumper RC
    Blood, 2010;116(16):2984-93.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  107. Lymphangiogenesis and angiogenesis: concurrence and/or dependence? Studies in inbred mouse strains.
    Authors: Nakao S, Maruyama K, Zandi S, Melhorn MI, Taher M, Noda K, Nusayr E, Doetschman T, Hafezi-Moghadam A
    FASEB J., 2010;24(2):504-13.
  108. Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis.
    Authors: Narazaki M, Segarra M, Hou X, Tanaka T, Li X, Tosato G
    Blood, 2010;116(16):3099-107.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  109. Angiopoietin-4 promotes glioblastoma progression by enhancing tumor cell viability and angiogenesis.
    Authors: Brunckhorst MK, Wang H, Lu R, Yu Q
    Cancer Res., 2010;70(18):7283-93.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  110. Macrophage inhibitory cytokine-1 regulates melanoma vascular development.
    Authors: Huh SJ, Chung CY, Sharma A
    Am. J. Pathol., 2010;176(6):2948-57.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  111. Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7.
    Authors: Jung DW, Che ZM, Kim J, Kim K, Kim KY, Williams D, Kim J
    Int. J. Cancer, 2010;127(2):332-44.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  112. Interleukin-27 acts as multifunctional antitumor agent in multiple myeloma.
    Authors: Cocco C, Giuliani N, Di Carlo E
    Clin. Cancer Res., 2010;16(16):4188-97.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  113. Vascular endothelial growth factor is crucial for erythropoietin-induced improvement of cardiac function in heart failure.
    Authors: Westenbrink BD, Ruifrok WP, Voors AA
    Cardiovasc. Res., 2010;87(1):30-9.
    Species: Rat
    Sample Type: Plasma
    Application: Bioassay
  114. The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain.
    Authors: Martino MM, Hubbell JA
    FASEB J., 2010;24(12):4711-21.
    Species: Human
    Sample Type: Recombinant Protein
    Application: Surface Plasmon Resonance
  115. Vitreous VEGF clearance is increased after vitrectomy.
    Authors: Lee SS, Ghosn C, Yu Z, Zacharias LC, Kao H, Lanni C, Abdelfattah N, Kuppermann B, Csaky KG, D'Argenio DZ, Burke JA, Hughes PM, Robinson MR
    Invest. Ophthalmol. Vis. Sci., 2010;51(4):2135-8.
    Species: Rabbit
    Sample Type: In Vivo
    Application: In Vivo
  116. The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.
    Authors: Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, Kodama T
    J. Clin. Invest., 2009;119(8):2257-70.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  117. Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property.
    Authors: Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, Azuma M, Kinoshita K, Batmunkh R, Rentsenhand B, Makino H, Ranjan P, Minakuchi K, Sone S
    J. Immunol., 2009;183(12):8176-85.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  118. Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases.
    Authors: Ye L, Chang JC, Lin C, Sun X, Yu J, Kan YW
    Proc. Natl. Acad. Sci. U.S.A., 2009;106(24):9826-30.
  119. Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis.
    Authors: Chen H, Campbell RA, Chang Y, Li M, Wang CS, Li J, Sanchez E, Share M, Steinberg J, Berenson A, Shalitin D, Zeng Z, Gui D, Perez-Pinera P, Berenson RJ, Said J, Bonavida B, Deuel TF, Berenson JR
    Blood, 2009;113(9):1992-2002.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  120. Sensitive and multiplexed detection of proteomic antigens via quantum dot aggregation.
    Authors: Soman C, Giorgio T,
    Nanomedicine, 2009;5(4):402-9.
    Species: N/A
    Sample Type: N/A
    Application: Quantum Dot
  121. Vascular endothelial growth factor-C (VEGF-C) promotes angiogenesis by induction of COX-2 in leukemic cells via the VEGF-R3/JNK/AP-1 pathway.
    Authors: Chien MH, Ku CC, Johansson G, Chen MW, Hsiao M, Su JL, Inoue H, Hua KT, Wei LH, Kuo ML
    Carcinogenesis, 2009;30(12):2005-13.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  122. Colocalization of the VEGF-R2 and the common IL-3/GM-CSF receptor beta chain to lipid rafts leads to enhanced p38 activation.
    Authors: Saulle E, Riccioni R, Coppola S, Parolini I, Diverio D, Riti V, Mariani G, Laufer S, Sargiacomo M, Testa U
    Br. J. Haematol., 2009;145(3):399-411.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  123. Hyperoxia disrupts vascular endothelial growth factor-nitric oxide signaling and decreases growth of endothelial colony-forming cells from preterm infants.
    Authors: Fujinaga H, Baker CD, Ryan SL, Markham NE, Seedorf GJ, Balasubramaniam V, Abman SH
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(6):L1160-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  124. Identification of protein kinase D2 as a pivotal regulator of endothelial cell proliferation, migration, and angiogenesis.
    Authors: Hao Q, Wang L, Zhao ZJ, Tang H
    J. Biol. Chem., 2009;284(2):799-806.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  125. Vascular endothelial growth factor drives autocrine epithelial cell proliferation and survival in chronic rhinosinusitis with nasal polyposis.
    Authors: Lee HS, Myers A, Kim J
    Am. J. Respir. Crit. Care Med., 2009;180(11):1056-67.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  126. Production of scFv antibody fragments from a hybridoma with functional activity against human vascular endothelial growth factor.
    Authors: Irani Y, Brereton HM, Tilton RG
    Hybridoma (Larchmt), 2009;28(3):205-9.
    Species: Human
    Sample Type: Cell Culture Supernates
    Application: Binding Assay
  127. Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells.
    Authors: Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T
    J. Biol. Chem., 2009;284(42):29109-24.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  128. The impact of proliferative potential of umbilical cord-derived endothelial progenitor cells and hypoxia on vascular tubule formation in vitro.
    Authors: Zhang Y, Fisher N, Newey SE
    Stem Cells Dev., 2009;18(2):359-75.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  129. DC-SIGN mediates cell-free infection and transmission of human T-cell lymphotropic virus type 1 by dendritic cells.
    Authors: Jain P, Manuel SL, Khan ZK, Ahuja J, Quann K, Wigdahl B
    J. Virol., 2009;83(21):10908-21.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  130. Angioinhibitory action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association.
    Authors: Sakai K, Nakamura T, Matsumoto K, Nakamura T
    J. Biol. Chem., 2009;284(33):22491-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  131. The hypoxia-inducible factor 1/NOR-1 axis regulates the survival response of endothelial cells to hypoxia.
    Authors: Martorell L, Gentile M, Rius J, Rodriguez C, Crespo J, Badimon L, Martinez-Gonzalez J
    Mol. Cell. Biol., 2009;29(21):5828-42.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  132. Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
    Authors: Hao Q, Wang L, Tang H
    Am. J. Physiol., Cell Physiol., 2009;296(4):C821-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  133. ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis.
    Authors: Gooz P, Gooz M, Baldys A, Hoffman S
    Biochem. Biophys. Res. Commun., 2009;380(1):33-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  134. VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo.
    Authors: Rennel ES, Varey AH, Churchill AJ, Wheatley ER, Stewart L, Mather S, Bates DO, Harper SJ
    Br. J. Cancer, 2009;101(7):1183-93.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  135. Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B.
    Authors: Lejmi E, Leconte L, Pedron-Mazoyer S, Ropert S, Raoul W, Lavalette S, Bouras I, Feron JG, Maitre-Boube M, Assayag F, Feumi C, Alemany M, Jie TX, Merkulova T, Poupon MF, Ruchoux MM, Tobelem G, Sennlaub F, Plouet J
    Proc. Natl. Acad. Sci. U.S.A., 2008;105(34):12491-6.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  136. Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
    Authors: Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY
    Nat. Med., 2008;14(4):448-53.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  137. Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis.
    Authors: Clerin V, Shih HH, Deng N, Hebert G, Resmini C, Shields KM, Feldman JL, Winkler A, Albert L, Maganti V, Wong A, Paulsen JE, Keith JC, Vlasuk GP, Pittman DD
    Atherosclerosis, 2008;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  138. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population.
    Authors: Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM
    Nature, 2008;453(7194):524-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  139. Transcriptional profiling of VEGF-A and VEGF-C target genes in lymphatic endothelium reveals endothelial-specific molecule-1 as a novel mediator of lymphangiogenesis.
    Authors: Shin JW, Huggenberger R, Detmar M
    Blood, 2008;112(6):2318-26.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  140. Development and validation of sandwich ELISA microarrays with minimal assay interference.
    Authors: Gonzalez RM, Seurynck-Servoss SL, Crowley SA
    J. Proteome Res., 2008;7(6):2406-14.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  141. Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth.
    Authors: Ebos JM, Lee CR, Bogdanovic E, Alami J, Van Slyke P, Francia G, Xu P, Mutsaers AJ, Dumont DJ, Kerbel RS
    Cancer Res., 2008;68(2):521-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  142. Plasma levels of soluble Tie2 and vascular endothelial growth factor distinguish critical limb ischemia from intermittent claudication in patients with peripheral arterial disease.
    Authors: Findley CM, Mitchell RG, Duscha BD, Annex BH, Kontos CD
    J. Am. Coll. Cardiol., 2008;52(5):387-93.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  143. Modulation of angiogenesis by a tetrameric tripeptide that antagonizes vascular endothelial growth factor receptor 1.
    Authors: Ponticelli S, Marasco D, Tarallo V, Albuquerque RJ, Mitola S, Takeda A, Stassen JM, Presta M, Ambati J, Ruvo M, De Falco S
    J. Biol. Chem., 2008;283(49):34250-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  144. BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy.
    Authors: Hilberg F, Roth GJ, Krssak M, Kautschitsch S, Sommergruber W, Tontsch-Grunt U, Garin-Chesa P, Bader G, Zoephel A, Quant J, Heckel A, Rettig WJ
    Cancer Res., 2008;68(12):4774-82.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  145. Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A.
    Authors: Narazaki M, Segarra M, Tosato G
    Blood, 2008;111(8):4126-36.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  146. Development of anti-atherosclerotic tissue-engineered blood vessel by A20-regulated endothelial progenitor cells seeding decellularized vascular matrix.
    Authors: Zhu C, Ying D, Mi J, Li L, Zeng W, Hou C, Sun J, Yuan W, Wen C, Zhang W
    Biomaterials, 2008;29(17):2628-36.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  147. Dopamine regulates endothelial progenitor cell mobilization from mouse bone marrow in tumor vascularization.
    Authors: Chakroborty D, Chowdhury UR, Sarkar C, Baral R, Dasgupta PS, Basu S
    J. Clin. Invest., 2008;118(4):1380-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  148. Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice.
    Authors: Zacchigna S, Pattarini L, Zentilin L, Moimas S, Carrer A, Sinigaglia M, Arsic N, Tafuro S, Sinagra G, Giacca M
    J. Clin. Invest., 2008;118(6):2062-75.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  149. Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression.
    Authors: Wanami LS, Chen HY, Peiro S, Garcia de Herreros A, Bachelder RE
    Exp. Cell Res., 2008;314(13):2448-53.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  150. The original Pathologische Anatomie Leiden-Endothelium monoclonal antibody recognizes a vascular endothelial growth factor binding site within neuropilin-1.
    Authors: Jaalouk DE, Ozawa MG, Sun J, Lahdenranta J, Schlingemann RO, Pasqualini R, Arap W
    Cancer Res., 2007;67(20):9623-9.
    Species: N/A
    Sample Type: Virus
    Application: Bioassay
  151. Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts.
    Authors: Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, Petrucci E, Cedrone M, Lo-Coco F, Foa R, Peschle C, Testa U
    Stem Cells, 2007;25(8):1862-71.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  152. Age- and dose-related effects on MSC engraftment levels and anatomical distribution in the central nervous systems of nonhuman primates: identification of novel MSC subpopulations that respond to guidance cues in brain.
    Authors: Isakova IA, Baker K, Dutreil M, Dufour J, Gaupp D, Phinney DG
    Stem Cells, 2007;25(12):3261-70.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Bioassay
  153. Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting.
    Authors: Pan Q, Chathery Y, Wu Y, Rathore N, Tong RK, Peale F, Bagri A, Tessier-Lavigne M, Koch AW, Watts RJ
    J. Biol. Chem., 2007;282(33):24049-56.
    Species: Human
    Sample Type: Recombinant Protein
    Application: Surface Plasmon Resonance
  154. Thrombopoietin enhances generation of CD34+ cells from human embryonic stem cells.
    Authors: Srivastava AS, Nedelcu E, Esmaeli-Azad B, Mishra R, Carrier E
    Stem Cells, 2007;25(6):1456-61.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  155. Ultrasensitive flow-based immunoassays using single-molecule counting.
    Authors: Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P
    Clin. Chem., 2007;53(11):1990-5.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  156. The F11 receptor (F11R/JAM-A) in atherothrombosis: overexpression of F11R in atherosclerotic plaques.
    Authors: Babinska A, Azari BM, Salifu MO, Liu R, Jiang XC, Sobocka MB, Boo D, Al Khoury G, Deitch JS, Marmur JD, Ehrlich YH, Kornecki E
    Thromb. Haemost., 2007;97(2):272-81.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  157. Fractalkine, a CX3C chemokine, as a mediator of ocular angiogenesis.
    Authors: You JJ, Yang CH, Huang JS, Chen MS, Yang CM
    Invest. Ophthalmol. Vis. Sci., 2007;48(11):5290-8.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  158. Enhancement of glucose transporter expression of brain endothelial cells by vascular endothelial growth factor derived from glioma exposed to hypoxia.
    Authors: Yeh WL, Lin CJ, Fu WM
    Mol. Pharmacol., 2007;73(1):170-7.
    Species: Rat
    Sample Type: Whole Cells
    Application: Bioassay
  159. Electronegative LDL impairs vascular endothelial cell integrity in diabetes by disrupting fibroblast growth factor 2 (FGF2) autoregulation.
    Authors: Lu J, Jiang W, Yang JH, Chang PY, Walterscheid JP, Chen HH, Marcelli M, Tang D, Lee YT, Liao WS, Yang CY, Chen CH
    Diabetes, 2007;57(1):158-66.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  160. Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
    Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
    Crit. Care Med., 2007;35(8):1955-60.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  161. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
    Authors: Ball SG, Shuttleworth CA, Kielty CM
    J. Cell Biol., 2007;177(3):489-500.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  162. Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure.
    Authors: Kissel CK, Lehmann R, Assmus B, Aicher A, Honold J, Fischer-Rasokat U, Heeschen C, Spyridopoulos I, Dimmeler S, Zeiher AM
    J. Am. Coll. Cardiol., 2007;49(24):2341-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  163. Impairment of the antifibrotic effect of hepatocyte growth factor in lung fibroblasts from African Americans: possible role in systemic sclerosis.
    Authors: Bogatkevich GS, Ludwicka-Bradley A, Highland KB, Hant F, Nietert PJ, Singleton CB, Feghali-Bostwick CA, Silver RM
    Arthritis Rheum., 2007;56(7):2432-42.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  164. Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells.
    Authors: Lin YL, Liang YC, Chiang BL
    J. Leukoc. Biol., 2007;82(6):1473-80.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  165. Evaluation of a xenogeneic VEGF vaccine in dogs with soft tissue sarcoma.
    Authors: Kamstock D, Elmslie R, Thamm D
    Cancer Immunol. Immunother., 2007;56(8):1299-309.
    Species: Canine
    Sample Type: In Vivo
    Application: In Vivo
  166. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells.
    Authors: Rajesh&lt;/LastName&gt;&lt;ForeNam D&lt;/Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF
    Stem Cells, 2007;25(2):490-9.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  167. Lymphatic reprogramming of microvascular endothelial cells by CEA-related cell adhesion molecule-1 via interaction with VEGFR-3 and Prox1.
    Authors: Kilic N, Oliveira-Ferrer L, Neshat-Vahid S, Irmak S, Obst-Pernberg K, Wurmbach JH, Loges S, Kilic E, Weil J, Lauke H, Tilki D, Singer BB, Ergun S
    Blood, 2007;110(13):4223-33.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  168. Glomerular endothelial glycocalyx constitutes a barrier to protein permeability.
    Authors: Singh A, Satchell SC, Neal CR
    J. Am. Soc. Nephrol., 2007;18(11):2885-93.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  169. Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth.
    Authors: Rogers MS, Christensen KA, Birsner AE, Short SM, Wigelsworth DJ, Collier RJ, D'Amato RJ
    Cancer Res., 2007;67(20):9980-5.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  170. Inhibition of hypoxia-induced increase of blood-brain barrier permeability by YC-1 through the antagonism of HIF-1alpha accumulation and VEGF expression.
    Authors: Yeh WL, Lu DY, Lin CJ, Liou HC, Fu WM
    Mol. Pharmacol., 2007;72(2):440-9.
    Species: Rat
    Sample Type: Whole Cells
    Application: Bioassay
  171. Interaction between Tie receptors modulates angiogenic activity of angiopoietin2 in endothelial progenitor cells.
    Authors: Kim KL, Shin IS, Kim JM, Choi JH, Byun J, Jeon ES, Suh W, Kim DK
    Cardiovasc. Res., 2006;72(3):394-402.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  172. Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells.
    Authors: Kurita R, Sasaki E, Yokoo T, Hiroyama T, Takasugi K, Imoto H, Izawa K, Dong Y, Hashiguchi T, Soda Y, Maeda T, Suehiro Y, Tanioka Y, Nakazaki Y, Tani K
    Stem Cells, 2006;24(9):2014-22.
    Species: Primate - Callitrix jacchus (Common Marmoset)
    Sample Type: Whole Cells
    Application: Bioassay
  173. Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells.
    Authors: Moreno MJ, Ball M, Andrade MF, McDermid A, Stanimirovic DB
    Glia, 2006;53(8):845-57.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  174. Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing.
    Authors: Jung Y, Wang J, Schneider A, Sun YX, Koh-Paige AJ, Osman NI, McCauley LK, Taichman RS
    Bone, 2006;38(4):497-508.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  175. Inhibitory Smad transcription factors protect arterial endothelial cells from apoptosis induced by BMP4.
    Authors: Kiyono M, Shibuya M
    Oncogene, 2006;25(54):7131-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  176. Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.
    Authors: Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, Czeiger D, Silverman WF, Belkin M, Battler A, Fulga V, Savion N
    Br. J. Haematol., 2006;135(5):703-14.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  177. Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism.
    Authors: Carr AN, Howard BW, Yang HT, Eby-Wilkens E, Loos P, Varbanov A, Qu A, DeMuth JP, Davis MG, Proia A, Terjung RL, Peters KG
    Cardiovasc. Res., 2006;69(4):925-35.
    Species: Rat
    Sample Type: In Vivo
    Application: In Vivo
  178. Bactericidal/permeability-increasing protein's signaling pathways and its retinal trophic and anti-angiogenic effects.
    Authors: Yamagata M, Rook SL, Sassa Y, Ma RC, Geraldes P, Goddard L, Clermont A, Gao B, Salti H, Gundel R, White M, Feener EP, Aiello LP, King GL
    FASEB J., 2006;20(12):2058-67.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  179. Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1.
    Authors: Lake AC, Vassy R, Di Benedetto M, Lavigne D, Le Visage C, Perret GY, Letourneur D
    J. Biol. Chem., 2006;281(49):37844-52.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  180. Regulation of Ang2 release by PTEN/PI3-kinase/Akt in lung microvascular endothelial cells.
    Authors: Tsigkos S, Zhou Z, Kotanidou A, Fulton D, Zakynthinos S, Roussos C, Papapetropoulos A
    J. Cell. Physiol., 2006;207(2):506-11.
    Species: Bovine
    Sample Type: Cell Culture Supernates
    Application: Bioassay
  181. Association between UHMWPE particle-induced inflammatory osteoclastogenesis and expression of RANKL, VEGF, and Flt-1 in vivo.
    Authors: Ren WP, Markel DC, Zhang R, Peng X, Wu B, Monica H, Wooley PH
    Biomaterials, 2006;27(30):5161-9.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  182. Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: conversion of cell columns into fibrovascular bundles.
    Authors: Anghelina M, Krishnan P, Moldovan L, Moldovan NI
    Am. J. Pathol., 2006;168(2):529-41.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  183. Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: a role for capturing hepatitis C virus particles.
    Authors: Lai WK, Sun PJ, Zhang J, Jennings A, Lalor PF, Hubscher S, McKeating JA, Adams DH
    Am. J. Pathol., 2006;169(1):200-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  184. Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A.
    Authors: Narazaki M, Tosato G
    Blood, 2006;107(10):3892-901.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  185. Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A.
    Authors: Nozaki M, Sakurai E, Raisler BJ, Baffi JZ, Witta J, Ogura Y, Brekken RA, Sage EH, Ambati BK, Ambati J
    J. Clin. Invest., 2006;116(2):422-9.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  186. Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration.
    Authors: Favier B, Alam A, Barron P, Bonnin J, Laboudie P, Fons P, Mandron M, Herault JP, Neufeld G, Savi P, Herbert JM, Bono F
    Blood, 2006;108(4):1243-50.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  187. Antagonists to human and mouse vascular endothelial growth factor receptor 2 generated by directed protein evolution in vitro.
    Authors: Getmanova EV, Chen Y, Bloom L, Gokemeijer J, Shamah S, Warikoo V, Wang J, Ling V, Sun L
    Chem. Biol., 2006;13(5):549-56.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  188. The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term.
    Authors: Bates DO, MacMillan PP, Manjaly JG, Qiu Y, Hudson SJ, Bevan HS, Hunter AJ, Soothill PW, Read M, Donaldson LF, Harper SJ
    Clin. Sci., 2006;110(5):575-85.
    Species: N/A
    Sample Type: N/A
    Application: WB Ctrl
  189. Multipotent adult progenitor cells from swine bone marrow.
    Authors: Zeng L, Rahrmann E, Hu Q, Lund T, Sandquist L, Felten M, O'Brien TD, O'Brien TD, Zhang J, Verfaillie C
    Stem Cells, 2006;24(11):2355-66.
    Species: Porcine
    Sample Type: Whole Cells
    Application: Bioassay
  190. Specific involvement of SRC family kinase activation in the pathogenesis of retinal neovascularization.
    Authors: Werdich XQ, Penn JS
    Invest. Ophthalmol. Vis. Sci., 2006;47(11):5047-56.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  191. Preclinical evaluation of antiangiogenic thrombospondin-1 peptide mimetics, ABT-526 and ABT-510, in companion dogs with naturally occurring cancers.
    Authors: Rusk A, McKeegan E, Haviv F, Majest S, Henkin J, Khanna C
    Clin. Cancer Res., 2006;12(24):7444-55.
    Species: Canine
    Sample Type: Whole Cells
    Application: Bioassay
  192. Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism.
    Authors: Carr AN, Howard BW, Yang HT, Eby-Wilkens E, Loos P, Varbanov A, Qu A, DeMuth JP, Davis MG, Proia A, Terjung RL, Peters KG
    Cardiovasc. Res., 2006;69(4):925-35.
    Species: Rat
    Sample Type: In Vivo
    Application: In Vivo
  193. Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells.
    Authors: Sreekumar PG, Kannan R, de Silva AT, Burton R, Ryan SJ, Hinton DR
    Biochem. Biophys. Res. Commun., 2006;346(4):1200-6.
    Species: N/A
    Sample Type: N/A
    Application: WB Ctrl
  194. Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells.
    Authors: Kim BK, Kim SE, Shim JH, Woo DH, Gil JE, Kim SK, Kim JH
    FEBS Lett., 2006;580(25):5869-74.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  195. Hepatocyte growth factor induces retinal vascular permeability via MAP-kinase and PI-3 kinase without altering retinal hemodynamics.
    Authors: Clermont AC, Cahill M, Salti H, Rook SL, Rask-Madsen C, Goddard L, Wong JS, Bursell D, Bursell SE, Aiello LP
    Invest. Ophthalmol. Vis. Sci., 2006;47(6):2701-8.
    Species: Rat
    Sample Type: In Vivo
    Application: In Vivo
  196. Osteoprotegerin (OPG)--a potential new role in the regulation of endothelial cell phenotype and tumour angiogenesis?
    Authors: Cross SS, Yang Z, Brown NJ, Balasubramanian SP, Evans CA, Woodward JK, Neville-Webbe HL, Lippitt JM, Reed MW, Coleman RE, Holen I
    Int. J. Cancer, 2006;118(8):1901-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  197. Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells.
    Authors: Hiroyama T, Miharada K, Aoki N, Fujioka T, Sudo K, Danjo I, Nagasawa T, Nakamura Y
    Exp. Hematol., 2006;34(6):760-9.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Type: Whole Cells
    Application: Bioassay
  198. Pericytes and endothelial precursor cells: cellular interactions and contributions to malignancy.
    Authors: Bagley RG, Weber W, Rouleau C, Teicher BA
    Cancer Res., 2005;65(21):9741-50.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  199. CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow.
    Authors: Curbishley SM, Eksteen B, Gladue RP, Lalor P, Adams DH
    Am. J. Pathol., 2005;167(3):887-99.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  200. Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis.
    Authors: Trevino JG, Summy JM, Gray MJ, Nilsson MB, Lesslie DP, Baker CH, Gallick GE
    Cancer Res., 2005;65(16):7214-22.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  201. Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.
    Authors: Dikov MM, Ohm JE, Ray N, Tchekneva EE, Burlison J, Moghanaki D, Nadaf S, Carbone DP
    J. Immunol., 2005;174(1):215-22.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  202. Human peripheral blood eosinophils induce angiogenesis.
    Authors: Puxeddu I, Alian A, Piliponsky AM, Ribatti D, Panet A, Levi-Schaffer F
    Int. J. Biochem. Cell Biol., 2005;37(3):628-36.
    Species: Chicken
    Sample Type: Whole Tissue
    Application: Bioassay
  203. Normalization of coronary microvascular reactivity and improvement in myocardial perfusion by surgical vascular endothelial growth factor therapy combined with oral supplementation of l-arginine in a porcine model of endothelial dysfunction.
    Authors: Voisine P, Bianchi C, Khan TA, Ruel M, Xu SH, Feng J, Li J, Malik T, Rosinberg A, Sellke FW
    J. Thorac. Cardiovasc. Surg., 2005;129(6):1414-20.
    Species: Porcine
    Sample Type: In Vivo
    Application: In Vivo
  204. Microvascular patterning is controlled by fine-tuning the Akt signal.
    Authors: Sun JF, Phung T, Shiojima I, Felske T, Upalakalin JN, Feng D, Kornaga T, Dor T, Dvorak AM, Walsh K, Benjamin LE
    Proc. Natl. Acad. Sci. U.S.A., 2005;102(1):128-33.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  205. Inhibition of tumor growth and angiogenesis by soluble EphB4.
    Authors: Martiny-Baron G, Korff T, Schaffner F, Esser N, Eggstein S, Marme D, Augustin HG
    Neoplasia, 2004;6(3):248-57.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  206. Angiopoietin 1 and vascular endothelial growth factor modulate human glomerular endothelial cell barrier properties.
    Authors: Satchell SC, Anderson KL, Mathieson PW
    J. Am. Soc. Nephrol., 2004;15(3):566-74.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  207. VEGF-promoted surgical angiogenesis in necrotic bone.
    Authors: Suzuki O, Bishop AT, Sunagawa T, Katsube K, Friedrich PF
    Microsurgery, 2004;24(1):85-91.
    Species: Rabbit
    Sample Type: In Vivo
    Application: In Vivo
  208. VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2.
    Authors: Usui T, Ishida S, Yamashiro K, Kaji Y, Poulaki V, Moore J, Moore T, Amano S, Horikawa Y, Dartt D, Golding M, Shima DT, Adamis AP
    Invest. Ophthalmol. Vis. Sci., 2004;45(2):368-74.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  209. GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice.
    Authors: Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, Marsh CB
    Immunity, 2004;21(6):831-42.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  210. Expansion of human SCID-repopulating cells under hypoxic conditions.
    Authors: Danet GH, Pan Y, Luongo JL, Bonnet DA, Simon MC
    J. Clin. Invest., 2003;112(1):126-35.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  211. Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells.
    Authors: Fuller T, Korff T, Kilian A, Dandekar G, Augustin HG
    J. Cell. Sci., 2003;116(0):2461-70.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  212. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.
    Authors: Maynard SE, Min JY, Merchan J, Lim KH, Mondal S, Stillman IE, Epstein FH, Karumanchi SA
    J. Clin. Invest., 2003;111(5):649-58.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  213. Malignant mesothelioma growth inhibition by agents that target the VEGF and VEGF-C autocrine loops.
    Authors: Masood R, Kundra A, Zhu S, Xia G, Scalia P, Smith DL, Gill PS
    Int. J. Cancer, 2003;104(5):603-10.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  214. Plasma angiopoietin-1, angiopoietin-2 and Tie-2 in breast and prostate cancer: a comparison with VEGF and Flt-1.
    Authors: Caine GJ, Blann AD, Stonelake PS, Ryan P, Lip GY
    Eur. J. Clin. Invest., 2003;33(10):883-90.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  215. Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein.
    Authors: Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R
    Int. J. Dev. Biol., 2003;47(1):15-29.
    Species: Xenopus
    Sample Type: In Vivo
    Application: In Vivo
  216. Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3.
    Authors: Barbour AP, Reeder JA, Walsh MD, Fawcett J, Antalis TM, Gotley DC
    Cancer Res., 2003;63(4):887-92.
    Species: Human
    Sample Type: Whole Cells
    Application: Binding Assay
  217. 17Beta-estradiol up-regulates vascular endothelial growth factor receptor-2 expression in human myometrial microvascular endothelial cells: role of estrogen receptor-alpha and -beta.
    Authors: Gargett CE, Zaitseva M, Bucak K, Chu S, Fuller PJ, Rogers PA
    J. Clin. Endocrinol. Metab., 2002;87(9):4341-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  218. Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome.
    Authors: Keane MP, Donnelly SC, Belperio JA, Goodman RB, Dy M, Burdick MD, Fishbein MC, Strieter RM
    J. Immunol., 2002;169(11):6515-21.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  219. Role of matrix metalloproteinase-9 in angiogenesis caused by ocular infection with herpes simplex virus.
    Authors: Lee S, Zheng M, Kim B, Rouse BT
    J. Clin. Invest., 2002;110(8):1105-11.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  220. VEGF signaling is required for the assembly but not the maintenance of embryonic blood vessels.
    Authors: Argraves WS, Larue AC, Fleming PA, Drake CJ
    Dev. Dyn., 2002;225(3):298-304.
    Species: Avian - Quail
    Sample Type: In Vivo
    Application: In Vivo
  221. Quantitative assessment of the integrity of the blood-retinal barrier in mice.
    Authors: Derevjanik NL, Vinores SA, Xiao WH, Mori K, Turon T, Hudish T, Dong S, Campochiaro PA
    Invest. Ophthalmol. Vis. Sci., 2002;43(7):2462-7.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  222. A critical role of placental growth factor in the induction of inflammation and edema formation.
    Authors: Oura H, Bertoncini J, Velasco P, Brown LF, Carmeliet P, Detmar M
    Blood, 2002;101(2):560-7.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  223. Antiangiogenic gene therapy for cancer via systemic administration of adenoviral vectors expressing secretable endostatin.
    Authors: Chen CT, Lin J, Li Q, Phipps SS, Jakubczak JL, Stewart DA, Skripchenko Y, Forry-Schaudies S, Wood J, Schnell C, Hallenbeck PL
    Hum. Gene Ther., 2000;11(14):1983-96.
  224. The dineolignan from Saururus chinensis, manassantin B, inhibits tumor-induced angiogenesis via downregulation of matrix metalloproteinases 9 in human endothelial cells.
    Authors: Liu, Zhaojie, Lu, Hong, Liu, Rong, Chen, Bin, Wang, Shan, Ma, Junchao, Fu, Jianjian
    Oncol Rep, 0;32(2):659-67.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
Expand to show all 224 Citations
Animal Component Free Recombinant Proteins
Description Application Cat# Citations Images  

Recombinant Human VEGF 165, ACFP Protein

BA ACFP293
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Have you used Recombinant Human VEGF 165 Protein, CF?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Order Details

  • Formulations

Contact Information

Calculators

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷
R&D Systems Guarantee

Customers Who Viewed
This Item Also Viewed

Feedback

Customer Information