Recombinant Mouse GM-CSF Protein 415-ML-010: R&D Systems

Recombinant Mouse GM-CSF Protein

(173 citations)
(4 Reviews)
  
  • Purity
    >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Endotoxin Level
    <1.0 EU per 1 μg of the protein by the LAL method.
  • Activity
    Measured in a cell proliferation assay using DA3 mouse myeloma cells. Ihle, J.N. et al. (1984) Advances in Viral Oncology. In G. Klein (eds): Raven Press, New York, NY. 4:95. The ED50 for this effect is 5‑30 pg/mL.
  • Source
    E. coli-derived Ala18-Lys141, with an N-terminal Met
  • Accession #
  • N-terminal Sequence
    Analysis
    Met
  • Predicted Molecular Mass
    14.3 kDa
Carrier Free
What does CF mean?
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
What formulation is right for me?
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
415-ML
 
415-ML/CF
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Data Images
Recombinant Mouse GM-CSF (Catalog # 415-ML) stimulates cell proliferation of the DA3 mouse myeloma cell line. The ED50 for this effect is 5-30 pg/mL.
1 μg/lane of Recombinant Mouse GM-CSF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.
Background: GM-CSF

GM-CSF was initially characterized as a factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GM-CSF is produced by a number of different cell types (including T cells, B cells, macrophages, mast cells, endothelial cells, fibroblasts, and adipocytes) in response to cytokine or inflammatory stimuli. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages, and eosinophils (1, 2). GM-CSF promotes a Th1 biased immune response, angiogenesis, allergic inflammation, and the development of autoimmunity (3-5). It shows clinical effectiveness in ameliorating chemotherapy-induced neutropenia, and GM-CSF transfected tumor cells are utilized as cancer vaccines (6, 7). The 22 kDa glycosylated GM-CSF, similar to IL-3 and IL-5, is a cytokine with a core of four bundled alpha ‑helices (8-10). Mature mouse GM-CSF shares 49%-54% amino acid sequence identity with canine, feline, human, and porcine GM-CSF and 69% with rat GM‑CSF. GM‑CSF exerts its biological effects through a heterodimeric receptor complex composed of GM-CSF R alpha /CD116 and the signal transducing common beta chain (CD131) which is also a component of the high-affinity receptors for IL-3 and IL-5 (11, 12). In addition, GM-CSF binds a naturally occurring soluble form of GM-CSF R alpha (13). The activity of GM-CSF is species specific between human and mouse. Mouse GM-CSF is only weakly active on rat cells, although rat GM‑CSF is fully active on mouse cells (14, 15).

  • References:
    1. Martinez-Moczygemba, M. and D.P. Huston (2003) J. Allergy Clin. Immunol. 112:653.
    2. Barreda, D.R. et al. (2004) Dev. Comp. Immunol. 28:509.
    3. Eksioglu, E.A. et al. (2007) Exp. Hematol. 35:1163.
    4. Cao, Y. (2007) J. Clin. Invest. 117:2362.
    5. Fleetwood, A.J. et al. (2005) Crit. Rev. Immunol. 25:405.
    6. Heuser, M. et al. (2007) Semin. Hematol. 44:148.
    7. Hege, K.M. et al. (2006) Int. Rev. Immunol. 25:321.
    8. Kaushansky, K. et al. (1992) Biochemistry 31:1881.
    9. Diederichs, K. et al. (1991) Science 254:1779.
    10. Gough, N.M. et al. (1984) Nature 309:763.
    11. Onetto-Pothier, N. et al. (1990) Blood 75:59.
    12. Hayashida, K. et al. (1990) Proc. Natl. Acad. Sci. 87:9655.
    13. Pelley, J.L. et al. (2007) Exp. Hematol. 35:1483.
    14. Oaks, M.K. et al. (1995) J. Interferon Cytokine Res. 15:1095.
    15. Vandenabeele, P. et al. (1990) Lymphokine Res. 9:381.
  • Long Name:
    Granulocyte Macrophage Growth Factor
  • Entrez Gene IDs:
    1437 (Human); 12981 (Mouse); 116630 (Rat); 397208 (Porcine); 403923 (Canine); 493805 (Feline)
  • Alternate Names:
    colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF; CSF2; GMCSF; GM-CSF; GMCSFgranulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897; molgramostin; sargramostim
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

173 Citations: Showing 1 - 10
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Species
Applications
Sample Type
  1. Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents
    Authors: OC Olson, H Kim, DF Quail, EA Foley, JA Joyce
    Cell Rep, 2017;19(1):101-113.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  2. A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors
    Authors: A Itoh-Nakad, M Matsumoto, H Kato, J Sasaki, Y Uehara, Y Sato, R Ebina-Shib, M Morooka, R Funayama, K Nakayama, K Ochiai, A Muto, K Igarashi
    Cell Rep, 2017;18(10):2401-2414.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  3. Therapeutic Effects of Methanol Extract from Euphorbia kansui Radix on Imiquimod-Induced Psoriasis
    Authors: SJ Kim, YW Jang, KE Hyung, DK Lee, KH Hyun, SY Park, ES Park, KW Hwang
    J Immunol Res, 2017;2017(0):7052560.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  4. Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex
    Authors: N Okamoto, K Mizote, H Honda, A Saeki, Y Watanabe, T Yamaguchi-, R Fukui, N Tanimura, Y Motoi, S Akashi-Tak, T Kato, S Fujishita, T Kimura, U Ohto, T Shimizu, T Hirokawa, K Miyake, K Fukase, Y Fujimoto, Y Nagai, K Takatsu
    J. Biol. Chem., 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  5. A heart-brain-kidney network controls adaptation to cardiac stress through tissue macrophage activation
    Authors: K Fujiu, M Shibata, Y Nakayama, F Ogata, S Matsumoto, K Noshita, S Iwami, S Nakae, I Komuro, R Nagai, I Manabe
    Nat. Med., 2017;23(5):611-622.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  6. Receptor Mincle promotes skin allergies and is capable of recognizing cholesterol sulfate
    Authors: AV Kostarnoy, PG Gancheva, B Lepenies, AI Tukhvatuli, AS Dzharullae, NB Polyakov, DA Grumov, DA Egorova, AY Kulibin, MA Bobrov, EA Malolina, PA Zykin, AI Soloviev, E Riabenko, DV Maltseva, DA Sakharov, AG Tonevitsky, LV Verkhovska, DY Logunov, BS Naroditsky, AL Gintsburg
    Proc. Natl. Acad. Sci. U.S.A, 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  7. Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection
    Authors: HC Watkins, CG Rappazzo, JS Higgins, X Sun, N Brock, A Chau, A Misra, JP Cannizzo, MR King, TR Maines, CA Leifer, GR Whittaker, MP DeLisa, D Putnam
    Mol. Ther, 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  8. Collagen scaffold microenvironments modulate cell lineage commitment for differentiation of bone marrow cells into regulatory dendritic cells
    Authors: Y Fang, B Wang, Y Zhao, Z Xiao, J Li, Y Cui, S Han, J Wei, B Chen, J Han, Q Meng, X Hou, J Luo, J Dai, Z Jing
    Sci Rep, 2017;7(0):42049.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  9. Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis in Pseudomonas Sepsis
    Authors: Q Pu, C Gan, R Li, Y Li, S Tan, X Li, Y Wei, L Lan, X Deng, H Liang, F Ma, M Wu
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  10. The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury
    Authors: C Zhang, S Wang, J Li, W Zhang, L Zheng, C Yang, T Zhu, R Rong
    Cell Death Dis, 2017;8(3):e2695.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  11. The influence of macrophage growth factors on Theiler's Murine Encephalomyelitis Virus (TMEV) infection and activation of macrophages
    Authors: KM Schneider, NB Watson, SB Minchenber, PT Massa
    Cytokine, 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  12. Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus
    Authors: AE Samarasing, RC Melo, S Duan, KS LeMessurie, S Liedmann, SL Surman, JJ Lee, JL Hurwitz, PG Thomas, JA McCullers
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  13. Functional paralysis of GM-CSF-derived bone marrow cells productively infected with ectromelia virus
    Authors: L Szulc-D?br, J Struzik, A Ostrowska, M Guzera, FN Toka, M Bossowska-, MM Giery?ska, A Winnicka, Z Nowak, MG Niemia?tow
    PLoS ONE, 2017;12(6):e0179166.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  14. Colony-stimulating factor 1 receptor blockade inhibits tumor growth by altering the polarization of tumor-associated macrophages in hepatocellular carcinoma
    Authors: JY Ao, XD Zhu, ZT Chai, H Cai, YY Zhang, KZ Zhang, LQ Kong, N Zhang, BG Ye, DN Ma, HC Sun
    Mol. Cancer Ther., 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  15. Inflammasome and Fas-Mediated IL-1? Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In Vivo
    Authors: R Uchiyama, S Yonehara, S Taniguchi, S Ishido, KJ Ishii, H Tsutsui
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  16. Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma
    Authors: DK Chiu, AP Tse, IM Xu, J Di Cui, RK Lai, LL Li, HY Koh, FH Tsang, LL Wei, CM Wong, IO Ng, CC Wong
    Nat Commun, 2017;8(1):517.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  17. The Development of Steady-State Activation Hubs between Adult LTi ILC3s and Primed Macrophages in Small Intestine
    Authors: AK Savage, HE Liang, RM Locksley
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  18. miR-181a and miR-150 regulate dendritic cell immune inflammatory responses and cardiomyocyte apoptosis via targeting JAK1-STAT1/c-Fos pathway
    Authors: J Zhu, K Yao, J Guo, H Shi, L Ma, Q Wang, H Liu, W Gao, A Sun, Y Zou, J Ge
    J. Cell. Mol. Med., 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  19. Soluble TNF Regulates TACE via AP-2? Transcription Factor in Mouse Dendritic Cells
    Authors: L Ge, NL Vujanovic
    J. Immunol., 2017;198(1):417-427.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  20. Ischemia/Reperfusion Induces Interferon Stimulated Gene Expression in Microglia
    Authors: A McDonough, RV Lee, S Noor, C Lee, T Le, M Iorga, JLH Phillips, S Murphy, T Möller, JR Weinstein
    J. Neurosci., 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  21. Cancer-derived Circulating MicroRNAs Promote Tumor Angiogenesis by Entering Dendritic Cells to Degrade Highly Complementary MicroRNAs
    Authors: J Wang, H Ye, D Zhang, K Cheng, Y Hu, X Yu, L Lu, J Hu, C Zuo, B Qian, Y Yu, S Liu, G Liu, C Mao, S Liu
    Theranostics, 2017;7(6):1407-1421.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  22. Enhancement of antitumor immunity by combination of anti-CTLA-4 antibody and radioimmunotherapy through the suppression of Tregs
    Authors: CH Son, J Bae, HR Lee, K Yang, YS Park
    Oncol Lett, 2017;13(5):3781-3786.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  23. A Lipid Based Antigen Delivery System Efficiently Facilitates MHC Class-I Antigen Presentation in Dendritic Cells to Stimulate CD8(+) T Cells
    Authors: Mithun Maji
    Sci Rep, 2016;6(0):27206.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  24. Alternatively activated macrophages determine repair of the infarcted adult murine heart
    J Clin Invest, 2016;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  25. Dendritic Cell-Like Cells Accumulate in Regenerating Murine Skeletal Muscle after Injury and Boost Adaptive Immune Responses Only upon a Microbial Challenge
    PLoS ONE, 2016;11(5):e0155870.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  26. Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU)
    PLoS ONE, 2016;11(5):e0155953.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  27. Liver X receptor and STAT1 cooperate downstream of Gas6/Mer to induce anti-inflammatory arginase 2 expression in macrophages
    Sci Rep, 2016;6(0):29673.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  28. CD8+ T cells produce a dialyzable antigen-specific activator of dendritic cells
    J Leukoc Biol, 2016;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  29. Powerful Complex Immunoadjuvant Based on Synergistic Effect of Combined TLR4 and NOD2 Activation Significantly Enhances Magnitude of Humoral and Cellular Adaptive Immune Responses
    PLoS ONE, 2016;11(5):e0155650.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  30. Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies
    Authors: Kei Suzuki
    PLoS ONE, 2016;11(6):e0156719.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  31. A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells
    Authors: Jonatan Ersching
    PLoS Pathog, 2016;12(6):e1005698.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  32. A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro
    Authors: Stefan Schülke
    J Immunol Res, 2016;2016(0):4156456.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassays
  33. Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function
    J Leukoc Biol, 2016;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  34. LRP1 modulates the microglial immune response via regulation of JNK and NF-?B signaling pathways
    J Neuroinflammation, 2016;13(1):304.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  35. Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia
    Oncogene, 2016;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  36. Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation
    J Clin Invest, 2016;0(0):.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  37. Cutting Edge: CLEC5A Mediates Macrophage Function and Chronic Obstructive Pulmonary Disease Pathologies
    Authors: BW Wortham, BL Eppert, JL Flury, SM Garcia, WR Donica, A Osterburg, B Joyce-Shai, DJ Cua, MT Borchers
    J. Immunol., 2016;196(8):3227-31.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  38. Aripiprazole inhibits polyI:C-induced microglial activation possibly via TRPM7
    Schizophr Res, 2016;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  39. Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart
    Eur J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  40. Bone Marrow CD11c+ Cell-Derived Amphiregulin Promotes Pulmonary Fibrosis
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  41. The Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoan Parasite Trypanosoma cruzi
    PLoS Pathog, 2016;12(4):e1005593.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  42. Hepatitis C Virus Stimulates Murine CD8?-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner
    PLoS Pathog, 2016;12(7):e1005736.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  43. IL-12p40/IL-10 Producing preCD8?/Clec9A+ Dendritic Cells Are Induced in Neonates upon Listeria monocytogenes Infection
    Authors: D Torres, A Köhler, S Delbauve, I Caminschi, MH Lahoud, K Shortman, V Flamand
    PLoS Pathog, 2016;12(4):e1005561.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  44. Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus
    Authors: Ahmed S Elshikha
    PLoS ONE, 2016;11(5):e0156583.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  45. CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: redefinition of murine common myeloid progenitor.
    Authors: Miyawaki K, Arinobu Y, Iwasaki H, Kohno K, Tsuzuki H, Iino T, Shima T, Kikushige Y, Takenaka K, Miyamoto T, Akashi K
    Stem Cells, 2015;33(3):976-87.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  46. Radiation-driven lipid accumulation and dendritic cell dysfunction in cancer.
    Authors: Gao F, Liu C, Guo J, Sun W, Xian L, Bai D, Liu H, Cheng Y, Li B, Cui J, Zhang C, Cai J
    Sci Rep, 2015;5(0):9613.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  47. Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling.
    Authors: Talaei N, Yu T, Manion K, Bremner R, Wither J
    J Immunol, 2015;195(10):4623-31.
  48. Tumor-Promoting Effects of Myeloid-Derived Suppressor Cells Are Potentiated by Hypoxia-Induced Expression of miR-210.
    Authors: Noman M, Janji B, Hu S, Wu J, Martelli F, Bronte V, Chouaib S
    Cancer Res, 2015;75(18):3771-87.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  49. Protease activity of Per a 10 potentiates Th2 polarization by increasing IL-23 and OX40L.
    Authors: Agrawal K, Kale S, Arora N
    Eur J Immunol, 2015;45(12):3375-85.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  50. Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion.
    Authors: Pamir N, Liu N, Irwin A, Becker L, Peng Y, Ronsein G, Bornfeldt K, Duffield J, Heinecke J
    J Biol Chem, 2015;290(23):14656-67.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  51. Glycogen Synthase Kinase-3beta (GSK-3beta) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-gamma-induced Indoleamine 2,3-Dioxygenase Expression.
    Authors: Noh K, Son K, Jung I, Kang T, Choi C, Park Y
    J Biol Chem, 2015;290(19):12394-402.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  52. TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
    Authors: Wang Y, Su L, Morin M, Jones B, Whitby L, Surakattula M, Huang H, Shi H, Choi J, Wang K, Moresco E, Berger M, Zhan X, Zhang H, Boger D, Beutler B
    Proc Natl Acad Sci U S A, 2015;113(7):E884-93.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  53. The renal microenvironment modifies dendritic cell phenotype.
    Authors: Chessa F, Mathow D, Wang S, Hielscher T, Atzberger A, Porubsky S, Gretz N, Burgdorf S, Grone H, Popovic Z
    Kidney Int, 2015;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  54. RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo.
    Authors: Ptaschinski C, Mukherjee S, Moore M, Albert M, Helin K, Kunkel S, Lukacs N
    PLoS Pathog, 2015;11(6):e1004978.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  55. Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis.
    Authors: Sahin E, Brunner J, Kral J, Kuttke M, Hanzl L, Datler H, Paar H, Neuwinger N, Saferding V, Zinser E, Halfmann A, Soukup K, Hainzl E, Lohmeyer T, Niederreiter B, Haider T, Dohnal A, Kronke G, Bluml S, Schabbauer G
    J Immunol, 2015;195(6):2560-70.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  56. Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation.
    Authors: Wertz I, Newton K, Seshasayee D, Kusam S, Lam C, Zhang J, Popovych N, Helgason E, Schoeffler A, Jeet S, Ramamoorthi N, Kategaya L, Newman R, Horikawa K, Dugger D, Sandoval W, Mukund S, Zindal A, Martin F, Quan C, Tom J, Fairbrother W, Townsend M, Warming S, DeVoss J, Liu J, Dueber E, Caplazi P, Lee W, Goodnow C, Balazs M, Yu K, Kolumam G, Dixit V
    Nature, 2015;528(7582):370-5.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  57. Sca-1+Lin-CD117- mesenchymal stem/stromal cells induce the generation of novel IRF8-controlled regulatory dendritic cells through Notch-RBP-J signaling.
    Authors: Liu X, Ren S, Ge C, Cheng K, Zenke M, Keating A, Zhao R
    J Immunol, 2015;194(9):4298-308.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  58. mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.
    Authors: Raich-Regue D, Rosborough B, Watson A, McGeachy M, Turnquist H, Thomson A
    J Immunol, 2015;194(10):4767-76.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  59. Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy.
    Authors: Schumacher A, Denecke B, Braunschweig T, Stahlschmidt J, Ziegler S, Brandenburg L, Stope M, Martincuks A, Vogt M, Gortz D, Camporeale A, Poli V, Muller-Newen G, Brummendorf T, Ziegler P
    J Hematol Oncol, 2015;8(0):64.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  60. CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia.
    Authors: Arieta Kuksin C, Gonzalez-Perez G, Minter L
    Blood, 2015;125(13):2087-94.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  61. Neutrophil priming occurs in a sequential manner and can be visualized in living animals by monitoring IL-1beta promoter activation.
    Authors: Yao Y, Matsushima H, Ohtola J, Geng S, Lu R, Takashima A
    J Immunol, 2015;194(3):1211-24.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  62. The generation of neutrophils in the bone marrow is controlled by autophagy.
    Authors: Rozman S, Yousefi S, Oberson K, Kaufmann T, Benarafa C, Simon H
    Cell Death Differ, 2015;22(3):445-56.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  63. An A2B Adenosine Receptor Agonist Promotes Th17 Autoimmune Responses in Experimental Autoimmune Uveitis (EAU) via Dendritic Cell Activation.
    Authors: Chen M, Liang D, Zuo A, Shao H, Kaplan H, Sun D
    PLoS ONE, 2015;10(7):e0132348.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  64. Decreased adipogenesis and adipose tissue in mice with inactivated protein phosphatase 5.
    Authors: Jacob W, Rosenzweig D, Vazquez-Martin C, Duce S, Cohen P
    Biochem J, 2015;466(0):163-76.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  65. Essential engagement of Toll-like receptor 2 in initiation of early protective Th1 response against rough variants of Mycobacterium abscessus.
    Authors: Kim J, Kang M, Kim W, Han S, Kim H, Kim H, Kwon K, Kim S, Cha S, Eum S, Koh W, Cho S, Park J, Shin S
    Infect Immun, 2015;83(4):1556-67.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  66. Complement receptor C5aR1/CD88 and dipeptidyl peptidase-4/CD26 define distinct hematopoietic lineages of dendritic cells.
    Authors: Nakano H, Moran T, Nakano K, Gerrish K, Bortner C, Cook D
    J Immunol, 2015;194(8):3808-19.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  67. Pneumococal Surface Protein A (PspA) Regulates Programmed Death Ligand 1 Expression on Dendritic Cells in a Toll-Like Receptor 2 and Calcium Dependent Manner.
    Authors: Vashishta M, Khan N, Mehto S, Sehgal D, Natarajan K
    PLoS ONE, 2015;10(7):e0133601.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  68. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection.
    Authors: Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, West J, Hansen K, Horan K, Jakobsen M, O'Hare P, Adler H, Sun R, Ploegh H, Damania B, Upton J, Fitzgerald K, Paludan S
    J Immunol, 2015;194(4):1819-31.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  69. Differential adjuvant activities of TLR7 and TLR9 agonists inversely correlate with nitric oxide and PGE2 production.
    Authors: Lee J, Martinez N, West K, Kornfeld H
    PLoS ONE, 2015;10(4):e0123165.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  70. MicroRNA-22 impairs anti-tumor ability of dendritic cells by targeting p38.
    Authors: Liang X, Liu Y, Mei S, Zhang M, Xin J, Zhang Y, Yang R
    PLoS ONE, 2015;10(3):e0121510.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  71. Immune suppressive effects of tonsil-derived mesenchymal stem cells on mouse bone-marrow-derived dendritic cells.
    Authors: Park, Minhwa, Kim, Yu-Hee, Ryu, Jung-Hwa, Woo, So-Youn, Ryu, Kyung-Ha
    Stem Cells Int, 2015;2015(0):106540.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  72. HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1.
    Authors: Wang H, Bei L, Shah C, Hu L, Eklund E
    J Immunol, 2015;194(11):5375-87.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  73. Targeting DNA vaccines to myeloid cells using a small peptide.
    Authors: Ye C, Choi J, Abraham S, Shankar P, Manjunath N
    Eur J Immunol, 2015;45(1):82-8.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  74. Immunosuppression in early postnatal days induces persistent and allergen-specific immune tolerance to asthma in adult mice.
    Authors: Chen, Yan, Zhang, Jin, Lu, Yong, Wang, Libo
    PLoS ONE, 2015;10(4):e0122990.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  75. Cytokine-induced killer cells co-cultured with dendritic cells loaded with the protein lysate produced by radiofrequency ablation induce a specific antitumor response.
    Authors: Shan, Chan-Cha, Shi, Liang-Ro, Ding, Mei-Qian, Zhu, Yi-Bei, Li, Xiao-Don, Xu, Bin, Jiang, Jing-Tin, Wu, Chang-Pi
    Oncol Lett, 2015;9(4):1549-1556.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  76. Soluble interleukin-15 complexes are generated in vivo by type I interferon dependent and independent pathways.
    Authors: Anthony S, Howard M, Hailemichael Y, Overwijk W, Schluns K
    PLoS ONE, 2015;10(3):e0120274.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  77. Hematopoietic stem/progenitor cells express several functional sex hormone receptors-novel evidence for a potential developmental link between hematopoiesis and primordial germ cells.
    Authors: Mierzejewska K, Borkowska S, Suszynska E, Suszynska M, Poniewierska-Baran A, Maj M, Pedziwiatr D, Adamiak M, Abdel-Latif A, Kakar S, Ratajczak J, Kucia M, Ratajczak M
    Stem Cells Dev, 2015;24(8):927-37.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  78. Aging is associated with increased regulatory T-cell function.
    Authors: Garg S, Delaney C, Toubai T, Ghosh A, Reddy P, Banerjee R, Yung R
    Aging Cell, 2014;13(3):441-8.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  79. MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity.
    Authors: Salama A, Fichou N, Allard M, Dubreil L, De Beaurepaire L, Viel A, Jegou D, Bosch S, Bach J
    PLoS ONE, 2014;9(9):e106153.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  80. Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease.
    Authors: Spoerl S, Mathew N, Bscheider M, Schmitt-Graeff A, Chen S, Mueller T, Verbeek M, Fischer J, Otten V, Schmickl M, Maas-Bauer K, Finke J, Peschel C, Duyster J, Poeck H, Zeiser R, von Bubnoff N
    Blood, 2014;123(24):3832-42.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  81. RIG-I modulates Src-mediated AKT activation to restrain leukemic stemness.
    Authors: Li X, Jiang L, Chen L, Ding M, Guo H, Zhang W, Zhang H, Ma X, Liu X, Xi X, Chen S, Chen Z, Zhu J
    Mol Cell, 2014;53(3):407-19.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  82. Characterization of the structure and immunostimulatory activity of a vaccine adjuvant, de-O-acylated lipooligosaccharide.
    Authors: Han, Ji Eun, Wui, Seo Ri, Kim, Kwang Su, Cho, Yang Je, Cho, Wan Je, Lee, Na Gyong
    PLoS ONE, 2014;9(1):e85838.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  83. Aged mice are unable to mount an effective myeloid response to sepsis.
    Authors: Nacionales D, Gentile L, Vanzant E, Lopez M, Cuenca A, Cuenca A, Ungaro R, Li Y, Baslanti T, Bihorac A, Moore F, Baker H, Leeuwenburgh C, Moldawer L, Efron P
    J Immunol, 2014;192(2):612-22.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  84. MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity.
    Authors: Benasciutti E, Mariani E, Oliva L, Scolari M, Perilli E, Barras E, Milan E, Orfanelli U, Fazzalari N, Campana L, Capobianco A, Otten L, Particelli F, Acha-Orbea H, Baruffaldi F, Faccio R, Sitia R, Reith W, Cenci S
    J Bone Miner Res, 2014;29(2):290-303.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  85. DNA demethylating agent 5-azacytidine inhibits myeloid-derived suppressor cells induced by tumor growth and cyclophosphamide treatment.
    Authors: Mikyskova R, Indrova M, Vlkova V, Bieblova J, Simova J, Parackova Z, Pajtasz-Piasecka E, Rossowska J, Reinis M
    J Leukoc Biol, 2014;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  86. Toll-like receptor 9 mediated responses in cardiac fibroblasts.
    Authors: Ohm I, Alfsnes K, Belland Olsen M, Ranheim T, Sandanger O, Dahl T, Aukrust P, Finsen A, Yndestad A, Vinge L
    PLoS ONE, 2014;9(8):e104398.
  87. Enhancement of tumor-specific T cell-mediated immunity in dendritic cell-based vaccines by Mycobacterium tuberculosis heat shock protein X.
    Authors: Jung I, Shin S, Lee M, Kang T, Han H, Lee S, Kim W, Kim H, Park W, Kim H, Yun C, Lee E, Wu T, Park Y
    J Immunol, 2014;193(3):1233-45.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  88. Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy.
    Authors: Wu L, Ong S, Talor M, Barin J, Baldeviano G, Kass D, Bedja D, Zhang H, Sheikh A, Margolick J, Iwakura Y, Rose N, Cihakova D
    J Exp Med, 2014;211(7):1449-64.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  89. RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance.
    Authors: Moraes-Vieira P, Yore M, Dwyer P, Syed I, Aryal P, Kahn B
    Cell Metab, 2014;19(3):512-26.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  90. Key role of microRNA in the regulation of granulocyte macrophage colony-stimulating factor expression in murine alveolar epithelial cells during oxidative stress.
    Authors: Sturrock, Anne, Mir-Kasimov, Mustafa, Baker, Jessica, Rowley, Jesse, Paine, Robert 3
    J Biol Chem, 2014;289(7):4095-105.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  91. Continuous retinoic acid induces the differentiation of mature regulatory monocytes but fails to induce regulatory dendritic cells.
    Authors: VanGundy, Zachary, Guerau-de-Arellano, Mireia, Baker, Julie D, Strange, Heather, Olivo-Marston, Susan, Muth, Dillon C, Papenfuss, Tracey L
    BMC Immunol, 2014;15(0):8.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  92. Tick-borne flaviviruses antagonize both IRF-1 and type I IFN signaling to inhibit dendritic cell function.
    Authors: Robertson S, Lubick K, Freedman B, Carmody A, Best S
    J Immunol, 2014;192(6):2744-55.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  93. Group B Streptococcus engages an inhibitory Siglec through sialic acid mimicry to blunt innate immune and inflammatory responses in vivo.
    Authors: Chang Y, Olson J, Beasley F, Tung C, Zhang J, Crocker P, Varki A, Nizet V
    PLoS Pathog, 2014;10(1):e1003846.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  94. Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases.
    Authors: Tseng J, Yang C, Liang S, Liu R, Yang S, Lin J, Chen Y, Wu Y, Jiang J, Lin C
    Clin Cancer Res, 2014;20(11):2885-97.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  95. Murine experimental autoimmune encephalomyelitis is diminished by treatment with the angiogenesis inhibitors B20-4.1.1 and angiostatin (K1-3).
    Authors: MacMillan C, Doucette C, Warford J, Furlong S, Hoskin D, Easton A
    PLoS ONE, 2014;9(2):e89770.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  96. Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses.
    Authors: Sahin E, Haubenwallner S, Kuttke M, Kollmann I, Halfmann A, Dohnal A, Chen L, Cheng P, Hoesel B, Einwallner E, Brunner J, Kral J, Schrottmaier W, Thell K, Saferding V, Bluml S, Schabbauer G
    J Immunol, 2014;193(4):1717-27.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  97. Preclinical to clinical translation of tofacitinib, a Janus kinase inhibitor, in rheumatoid arthritis.
    Authors: Dowty, Martin E, Jesson, Michael, Ghosh, Sarbani, Lee, Jamie, Meyer, Debra M, Krishnaswami, Sriram, Kishore, Nandini
    J Pharmacol Exp Ther, 2014;348(1):165-73.
    Species: Mouse
    Sample Type: Whole Blood
    Application: Bioassay
  98. Acanthamoeba protease activity promotes allergic airway inflammation via protease-activated receptor 2.
    Authors: Park, Mi Kyung, Cho, Min Kyou, Kang, Shin Ae, Park, Hye-Kyun, Kim, Dong-Hee, Yu, Hak Sun
    PLoS ONE, 2014;9(3):e92726.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  99. Semapimod sensitizes glioblastoma tumors to ionizing radiation by targeting microglia.
    Authors: Miller, Ian S, Didier, Sebastie, Murray, David W, Turner, Tia H, Issaivanan, Magimair, Ruggieri, Rosamari, Al-Abed, Yousef, Symons, Marc
    PLoS ONE, 2014;9(5):e95885.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  100. The glycosylated Rv1860 protein of mycobacterium tuberculosis inhibits dendritic cell mediated TH1 and TH17 polarization of T cells and abrogates protective immunity conferred by BCG.
    Authors: Satchidanandam V, Kumar N, Jumani R, Challu V, Elangovan S, Khan N
    PLoS Pathog, 2014;10(6):e1004176.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  101. Embryonic stem cell-derived haematopoietic progenitor cells down-regulate the CD3 xi chain on T cells, abrogating alloreactive T cells.
    Authors: Kim E, Miyake B, Aggarwal M, Voetlause R, Griffith M, Zavazava N
    Immunology, 2014;142(3):421-30.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  102. Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity.
    Authors: Nagareddy P, Kraakman M, Masters S, Stirzaker R, Gorman D, Grant R, Dragoljevic D, Hong E, Abdel-Latif A, Smyth S, Choi S, Korner J, Bornfeldt K, Fisher E, Dixit V, Tall A, Goldberg I, Murphy A
    Cell Metab, 2014;19(5):821-35.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  103. PD-L1 is a novel direct target of HIF-1alpha, and its blockade under hypoxia enhanced MDSC-mediated T cell activation.
    Authors: Noman M, Desantis G, Janji B, Hasmim M, Karray S, Dessen P, Bronte V, Chouaib S
    J Exp Med, 2014;211(5):781-90.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  104. Subcapsular sinus macrophages limit dissemination of West Nile virus particles after inoculation but are not essential for the development of West Nile virus-specific T cell responses.
    Authors: Winkelmann E, Widman D, Xia J, Johnson A, Van Rooijen N, Mason P, Bourne N, Milligan G
    Virology, 2014;450(0):278-89.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  105. GM-CSF-responsive monocyte-derived dendritic cells are pivotal in Th17 pathogenesis.
    Authors: Ko H, Brady J, Ryg-Cornejo V, Hansen D, Vremec D, Shortman K, Zhan Y, Lew A
    J Immunol, 2014;192(5):2202-9.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  106. Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis.
    Authors: Boettcher S, Gerosa R, Radpour R, Bauer J, Ampenberger F, Heikenwalder M, Kopf M, Manz M
    Blood, 2014;124(9):1393-403.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  107. Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
    Authors: Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C
    J Immunol, 2014;192(8):3569-81.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  108. Colony-stimulating factor-1 signaling suppresses renal crystal formation.
    Authors: Taguchi K, Okada A, Kitamura H, Yasui T, Naiki T, Hamamoto S, Ando R, Mizuno K, Kawai N, Tozawa K, Asano K, Tanaka M, Miyoshi I, Kohri K
    J Am Soc Nephrol, 2014;25(8):1680-97.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  109. Cytokine conditioning enhances systemic delivery and therapy of an oncolytic virus.
    Authors: Ilett E, Kottke T, Donnelly O, Thompson J, Willmon C, Diaz R, Zaidi S, Coffey M, Selby P, Harrington K, Pandha H, Melcher A, Vile R
    Mol Ther, 2014;22(10):1851-63.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  110. Maltose-binding protein fusion allows for high level bacterial expression and purification of bioactive mammalian cytokine derivatives.
    Authors: Pennati A, Deng J, Galipeau J
    PLoS ONE, 2014;9(9):e106724.
    Species: N/A
    Sample Type: N/A
    Application: WB Standard
  111. TRAF5 negatively regulates TLR signaling in B lymphocytes.
    Authors: Buchta C, Bishop G
    J Immunol, 2014;192(1):145-50.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  112. DHX15 senses double-stranded RNA in myeloid dendritic cells.
    Authors: Lu H, Lu N, Weng L, Yuan B, Liu Y, Zhang Z
    J Immunol, 2014;193(3):1364-72.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  113. The leukemia-associated Mll-Ell oncoprotein induces fibroblast growth factor 2 (Fgf2)-dependent cytokine hypersensitivity in myeloid progenitor cells.
    Authors: Shah, Chirag A, Bei, Ling, Wang, Hao, Platanias, Leonidas, Eklund, Elizabet
    J Biol Chem, 2013;288(45):32490-505.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  114. Tetraspanin CD37 contributes to the initiation of cellular immunity by promoting dendritic cell migration.
    Authors: Gartlan K, Wee J, Demaria M, Nastovska R, Chang T, Jones E, Apostolopoulos V, Pietersz G, Hickey M, van Spriel A, Wright M
    Eur J Immunol, 2013;43(5):1208-19.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  115. Emulsified phosphatidylserine, simple and effective peptide carrier for induction of potent epitope-specific T cell responses.
    Authors: Ichihashi, Toru, Satoh, Toshifum, Sugimoto, Chihiro, Kajino, Kiichi
    PLoS ONE, 2013;8(3):e60068.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  116. Functional education of invariant NKT cells by dendritic cell tuning of SHP-1.
    Authors: Napolitano, Anna, Pittoni, Paola, Beaudoin, Lucie, Lehuen, Agnes, Voehringer, David, MacDonald, H Robson, Dellabona, Paolo, Casorati, Giulia
    J Immunol, 2013;190(7):3299-308.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  117. Differential requirements of CD4(+) T-cell signals for effector cytotoxic T-lymphocyte (CTL) priming and functional memory CTL development at higher CD8(+) T-cell precursor frequency.
    Authors: Umeshappa C, Nanjundappa R, Xie Y, Freywald A, Xu Q, Xiang J
    Immunology, 2013;138(4):298-306.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  118. Radiation-induced loss of cell surface CD47 enhances immune-mediated clearance of human papillomavirus-positive cancer.
    Authors: Vermeer D, Spanos W, Vermeer P, Bruns A, Lee K, Lee J
    Int J Cancer, 2013;133(1):120-9.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  119. Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis.
    Authors: Kumar M, Roe K, Orillo B, Muruve D, Nerurkar V, Gale M, Verma S
    J Virol, 2013;87(7):3655-67.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  120. Fas-associated phosphatase 1 (Fap1) influences betacatenin activity in myeloid progenitor cells expressing the Bcr-abl oncogene.
    Authors: Huang W, Bei L, Eklund E
    J Biol Chem, 2013;288(18):12766-76.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  121. Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers.
    Authors: Elcombe S, Naqvi S, van den Bosch M, Mackenzie K, Cianfanelli F, Brown G, Arthur J
    PLoS ONE, 2013;8(3):e60086.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  122. Inefficient TLR4/MD-2 heterotetramerization by monophosphoryl lipid A.
    Authors: Casella C, Mitchell T
    PLoS ONE, 2013;8(4):e62622.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  123. Deletion of CD74, a putative MIF receptor, in mice enhances osteoclastogenesis and decreases bone mass.
    Authors: Mun S, Won H, Hernandez P, Aguila H, Lee S
    J Bone Miner Res, 2013;28(4):948-59.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  124. PGI(2) signaling inhibits antigen uptake and increases migration of immature dendritic cells.
    Authors: Toki S, Goleniewska K, Huckabee M, Zhou W, Newcomb D, FitzGerald G, Lawson W, Peebles R
    J Leukoc Biol, 2013;94(1):77-88.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  125. Borrelia burgdorferi elicited-IL-10 suppresses the production of inflammatory mediators, phagocytosis, and expression of co-stimulatory receptors by murine macrophages and/or dendritic cells.
    Authors: Chung Y, Zhang N, Wooten R
    PLoS ONE, 2013;8(12):e84980.
    Species: Mouse
    Sample Type: Whole Tissue
    Application: Bioassay
  126. NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through reduction-oxidation regulation of NF-kappaB activity.
    Authors: Han W, Li H, Cai J, Gleaves L, Polosukhin V, Segal B, Yull F, Blackwell T
    J Immunol, 2013;190(9):4786-94.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  127. Prostate cancer stem cells are targets of both innate and adaptive immunity and elicit tumor-specific immune responses.
    Authors: Jachetti, Elena, Mazzoleni, Stefania, Grioni, Matteo, Ricupito, Alessia, Brambillasca, Chiara, Generoso, Luca, Calcinotto, Arianna, Freschi, Massimo, Mondino, Anna, Galli, Rossella, Bellone, Matteo
    Oncoimmunology, 2013;2(5):e24520.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  128. Respiratory syncytial virus infection modifies and accelerates pulmonary disease via DC activation and migration.
    Authors: Jang, Sihyug, Smit, Joost, Kallal, Lara E, Lukacs, Nicholas
    J Leukoc Biol, 2013;94(1):5-15.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  129. Intravaginal TLR agonists increase local vaccine-specific CD8 T cells and human papillomavirus-associated genital-tumor regression in mice.
    Authors: Domingos-Pereira S, Decrausaz L, Derre L, Bobst M, Romero P, Schiller J, Jichlinski P, Nardelli-Haefliger D
    Mucosal Immunol, 2013;6(2):393-404.
    Species: Mouse
    Sample Type: Tissue Homogenates
    Application: Bioassay
  130. Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery.
    Authors: Jacome-Galarza C, Lee S, Lorenzo J, Aguila H
    J Bone Miner Res, 2013;28(5):1203-13.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  131. Mycobacterium tuberculosis RpfB drives Th1-type T cell immunity via a TLR4-dependent activation of dendritic cells.
    Authors: Kim J, Kim W, Choi H, Jang B, Lee K, Park J, Kim H, Cho S, Shin S
    J Leukoc Biol, 2013;94(4):733-49.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  132. GSK3beta regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement.
    Authors: Lapid K, Itkin T, D'Uva G, Ovadya Y, Ludin A, Caglio G, Kalinkovich A, Golan K, Porat Z, Zollo M, Lapidot T
    J Clin Invest, 2013;123(4):1705-17.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  133. Protein kinase C delta (PKCdelta)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascade regulates glycogen synthase kinase-3 (GSK-3) inhibition-mediated interleukin-10 (IL-10) expression in lipopolysaccharide (LPS)-induced endotoxemia.
    Authors: Noh KT, Son KH, Jung ID, Kang HK, Hwang SA, Lee WS, You JC, Park YM
    J. Biol. Chem., 2012;287(17):14226-33.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  134. The MSHA Strain of Pseudomonas Aeruginosa Activated TLR Pathway and Enhanced HIV-1 DNA Vaccine Immunoreactivity.
    Authors: Hou J, Liu Y, Liu Y, Shao Y
    PLoS ONE, 2012;7(10):e47724.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  135. Macrophages participate in IL-17-mediated inflammation.
    Authors: Barin JG, Baldeviano GC, Talor MV, Wu L, Ong S, Quader F, Chen P, Zheng D, Caturegli P, Rose NR, Cihakova D
    Eur. J. Immunol., 2012;42(3):726-36.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  136. Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function.
    Authors: Charles, Julia F, Hsu, Lih-Yun, Niemi, Erene C, Weiss, Arthur, Aliprantis, Antonios, Nakamura, Mary C
    J Clin Invest, 2012;122(12):4592-605.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  137. Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands.
    Authors: Munich S, Sobo-Vujanovic A, Buchser W, Beer-Stolz D, Vujanovic N
    Oncoimmunology, 2012;1(7):1074-1083.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  138. Regulation of innate CD8+ T-cell activation mediated by cytokines.
    Proc Natl Acad Sci U S A, 2012;109(25):9971-6.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  139. Breast regression protein-39 (BRP-39) promotes dendritic cell maturation in vitro and enhances Th2 inflammation in murine model of asthma.
    Authors: Xu Q, Chai S, Qian Y, Zhang M, Wang K
    Acta Pharmacol Sin, 2012;33(12):1525-32.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Cell Culture Substrate
  140. Dysregulation in Retinal Para-Inflammation and Age-Related Retinal Degeneration in CCL2 or CCR2 Deficient Mice.
    Authors: Chen M, Forrester JV, Xu H
    PLoS ONE, 2011;6(8):e22818.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  141. Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells.
    Authors: Kinzfogl J, Hangoc G, Broxmeyer HE
    Blood, 2011;118(3):565-75.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  142. Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment.
    Authors: Cook BD, Liu S, Evans T
    Blood, 2011;117(24):6489-97.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  143. CCL20/CCR6 blockade enhances immunity to RSV by impairing recruitment of DC.
    Authors: Kallal LE, Schaller MA, Lindell DM, Lira SA, Lukacs NW
    Eur. J. Immunol., 2010;40(4):1042-52.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  144. Oncostatin M induces dendritic cell maturation and Th1 polarization.
    Authors: Jung ID, Noh KT, Lee CM, Chun SH, Jeong SK, Park JW, Park WS, Kim HW, Yun CH, Shin YK, Park YM
    Biochem. Biophys. Res. Commun., 2010;394(2):272-8.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Media Supplement - Cell Prep
  145. p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumonia.
    Authors: Liu Q, Cheng LI, Yi L, Zhu N, Wood A, Changpriroa CM, Ward JM, Jackson SH
    Am. J. Pathol., 2009;174(1):153-63.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  146. Critical roles of inflammation and apoptosis in improved survival in a model of hyperoxia-induced acute lung injury in Pneumocystis murina-infected mice.
    Authors: Beck JM, Preston AM, Wilcoxen SE, Morris SB, Sturrock A, Paine R
    Infect. Immun., 2009;77(3):1053-60.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  147. The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation.
    Authors: Claudio E, Sonder SU, Saret S, Carvalho G, Ramalingam TR, Wynn TA, Chariot A, Garcia-Perganeda A, Leonardi A, Paun A, Chen A, Ren NY, Wang H, Siebenlist U
    J. Immunol., 2009;182(3):1617-30.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  148. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing.
    Authors: Fukui R, Saitoh S, Matsumoto F, Kozuka-Hata H, Oyama M, Tabeta K, Beutler B, Miyake K
    J. Exp. Med., 2009;206(6):1339-50.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  149. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice.
    Authors: Guo B, Chang EY, Cheng G
    J. Clin. Invest., 2008;118(5):1680-90.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  150. Adenosine receptors in regulation of dendritic cell differentiation and function.
    Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
    Blood, 2008;112(5):1822-31.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  151. Lipopolysaccharide-activated IL-10-secreting dendritic cells suppress experimental autoimmune uveoretinitis by MHCII-dependent activation of CD62L-expressing regulatory T cells.
    Authors: Lau AW, Biester S, Cornall RJ, Forrester JV
    J. Immunol., 2008;180(6):3889-99.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  152. Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.
    Authors: Gaudreau S, Guindi C, Menard M, Besin G, Dupuis G, Amrani A
    J. Immunol., 2007;179(6):3638-47.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  153. The endothelial cell-produced antiangiogenic cytokine vascular endothelial growth inhibitor induces dendritic cell maturation.
    Authors: Tian F, Grimaldo S, Fujita M, Fugita M, Cutts J, Vujanovic NL, Li LY
    J. Immunol., 2007;179(6):3742-51.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  154. Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells.
    Authors: Kurooka M, Kaneda Y
    Cancer Res., 2007;67(1):227-36.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  155. Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines.
    Authors: Koya RC, Kimura T, Ribas A, Rozengurt N, Lawson GW, Faure-Kumar E, Wang HJ, Herschman H, Kasahara N, Stripecke R
    Mol. Ther., 2007;15(5):971-80.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  156. Angiostatin inhibits monocyte/macrophage migration via disruption of actin cytoskeleton.
    Authors: Perri SR, Annabi B, Galipeau J
    FASEB J., 2007;21(14):3928-36.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  157. Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells.
    Authors: Sugiyama K, Shirai R, Mukae H, Ishimoto H, Nagata T, Sakamoto N, Ishii H, Nakayama S, Yanagihara K, Mizuta Y, Kohno S
    Clin. Exp. Immunol., 2007;147(3):540-6.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  158. Bv8 regulates myeloid-cell-dependent tumour angiogenesis.
    Authors: Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N
    Nature, 2007;450(7171):825-31.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  159. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
    Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
    Immunity, 2007;26(4):445-59.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  160. A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex.
    Authors: Rafei M, Wu JH, Annabi B, Lejeune L, Francois M, Galipeau J
    Blood, 2007;109(5):2234-42.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  161. B7-DC induced by IL-13 works as a feedback regulator in the effector phase of allergic asthma.
    Authors: Matsumoto K, Fukuyama S, Eguchi-Tsuda M, Nakano T, Matsumoto T, Matsumura M, Moriwaki A, Kan-o K, Wada Y, Yagita H, Shin T, Pardoll DM, Patcharee R, Azuma M, Nakanishi Y, Inoue H
    Biochem. Biophys. Res. Commun., 2007;365(1):170-5.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  162. Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation.
    Authors: Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X
    Biochem. Biophys. Res. Commun., 2006;345(3):1122-30.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  163. Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.
    Authors: Kim SY, Nguyen AD, Gao JL, Murphy PM, Mansfield BC, Chou JY
    J. Biol. Chem., 2006;281(39):28794-801.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  164. Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.
    Authors: Dikov MM, Ohm JE, Ray N, Tchekneva EE, Burlison J, Moghanaki D, Nadaf S, Carbone DP
    J. Immunol., 2005;174(1):215-22.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  165. GM-CSF action in the CNS decreases food intake and body weight.
    Authors: Reed JA, Clegg DJ, Smith KB, Tolod-Richer EG, Matter EK, Picard LS, Seeley RJ
    J. Clin. Invest., 2005;115(11):3035-44.
    Species: Rat
    Sample Type: In Vivo
    Application: In Vivo
  166. Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.
    Authors: Wada A, Tada Y, Shimozato O, Takiguchi Y, Tatsumi K, Kuriyama T, Tagawa M
    Anticancer Res., 2005;25(1):299-303.
  167. NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs.
    Authors: Borg C, Jalil A, Laderach D, Maruyama K, Wakasugi H, Charrier S, Ryffel B, Cambi A, Figdor C, Vainchenker W, Galy A, Caignard A, Zitvogel L
    Blood, 2004;104(10):3267-75.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  168. Robust conversion of marrow cells to skeletal muscle with formation of marrow-derived muscle cell colonies: a multifactorial process.
    Authors: Abedi M, Greer DA, Colvin GA, Demers DA, Dooner MS, Harpel JA, Weier HU, Lambert JF, Quesenberry PJ
    Exp. Hematol., 2004;32(5):426-34.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  169. Dendritic cells phagocytose and are activated by Treponema pallidum.
    Authors: Bouis DA, Popova TG, Takashima A, Norgard MV
    Infect. Immun., 2001;69(1):518-28.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  170. Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function.
    Authors: Gabrilovich DI, Ishida T, Nadaf S, Ohm JE, Carbone DP
    Clin. Cancer Res., 1999;5(10):2963-70.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  171. Stem cell factor improves the repopulating ability of primitive hematopoietic stem cells after sublethal irradiation (and, to a lesser extent) after bone marrow transplantation in mice.
    Authors: Gardner RV, 48657, Oliver P, Astle CM
    Involvement of ?-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum, 1998;16(2):112-9.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  172. Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation.
    Authors: Liu F, Poursine-Laurent J, Wu HY, Link DC
    Blood, 1997;90(7):2583-90.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  173. TLR2 deletion promotes arthritis through reduction of IL-10.
    Authors: Huang Q, Koessler R, Birkett R, Perlman H, Xing L, Pope R
    J Leukoc Biol, 0;93(5):751-9.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
Expand to show all 173 Citations
Animal-Free Recombinant Proteins
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Recombinant Mouse GM-CSF, Animal-Free Protein

BA AFL415
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Average Rating: 4.3 (Based on 4 reviews)

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We have 4 reviews tested in 3 applications: Stem/Immune cell maintenance or differentiation , In vitro bioactivity in cell culture, Cell Adhesion.
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 Stem/Immune cell maintenance or differentiation Anonymous 08/03/2016
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ApplicationStem/Immune cell maintenance or differentiation
  Excellent
 Stem/Immune cell maintenance or differentiation Anonymous 05/16/2016
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ApplicationStem/Immune cell maintenance or differentiation
Reason for Ratinguse this product on a weekly basis for my BMDC experiments. Works consistently and cells looks great.
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 In vitro bioactivity in cell culture Anonymous 01/21/2016
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ApplicationIn vitro bioactivity in cell culture
  Excellent
 Cell Adhesion Anonymous 01/14/2016
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ApplicationCell Adhesion
Reason for RatingThe mouse GM-CSF constantly work good for the experiments. The product is reliable and with high quality.

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