Recombinant Mouse SCF Protein

Formulations:
Catalog # Availability Size / Price Qty
455-MC-010
455-MC-050
455-MC-500
455-MC-020
455-MC-100
Recombinant Mouse SCF Protein Bioactivity
2 Images
Product Details
Citations (135)
FAQs
Reviews

Recombinant Mouse SCF Protein Summary

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323. The ED50 for this effect is 2.5-10 ng/mL.
Source
E. coli-derived mouse SCF/c-kit Ligand protein
Lys26-Ala189, with an N-terminal Met
Accession #
N-terminal Sequence
Analysis
Met
Predicted Molecular Mass
18.6 kDa

Product Datasheets

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

455-MC

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

455-MC/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Data Images

Bioactivity View Larger

Recombinant Mouse SCF/c-kit Ligand (Catalog # 455-MC) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED50for this effect is 2.5-10 ng/mL.

SDS-PAGE View Larger

1 μg/lane of Recombinant Mouse SCF/c-kit was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 19 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: SCF/c-kit Ligand

Stem cell factor (SCF), also known as c-kit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28 - 40 kDa type I transmembrane glycoprotein (1). It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors (1 - 7). SCF is a primary growth and activation factor for mast cells and eosinophils (8). Mature mouse SCF consists of a 189 amino acid (aa) extracellular domain (ECD), a 23 aa transmembrane segment, and a 36 aa cytoplasmic tail (9). The ECD shows both N-linked and O-linked glycosylation (10). Proteolytic cleavage at two alternate sites in the extracellular juxtamembrane region releases a 25 kDa soluble molecule which is comparable to the only form produced by Steel-dickie mutant mice (11, 12). An alternately spliced isoform of mouse SCF lacks 28 aa that encompasses the primary proteolytic recognition site (13). Within the ECD of the short isoform (corresponding to this recombinant protein), mouse SCF shares 93% aa sequence identity with rat SCF and 72% - 75% with canine, feline, and human SCF. Rat SCF is active on mouse and human cells, but human SCF is only weakly active on mouse cells (14). Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/c-kit to trigger receptor dimerization and signaling (15). SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels (16).

References
  1. Ashman, L.K. (1999) Int. J. Biochem. Cell Biol. 31:1037.
  2. Sette, C. et al. (2000) Int. J. Dev. Biol. 44:599. 
  3. Yoshida, H. et al. (2001) J. Invest. Dermatol. Symp. Proc. 6:1.
  4. Erlandsson, A. et al. (2004) Exp. Cell Res. 301:201. 
  5. Kapur, R. et al. (2002) Blood 100:1287.
  6. Wang, C.-H. et al. (2007) Arterioscler. Thromb. Vasc. Biol. 27:540.
  7. Bashamboo, A. et al. (2006) J. Cell Sci. 119:3039. 
  8. Reber, L. et al. (2006) Eur. J. Pharmacol. 533:327. 
  9. Huang, E. et al. (1990) Cell 63:225.
  10. Arakawa, T. et al. (1991) J. Biol. Chem. 266:18942.
  11. Majumdar, M.K. et al. (1994) J. Biol. Chem. 269:1237.
  12. Brannan, C.I. et al. (1991) Proc. Natl. Acad. Sci. 88:4671.
  13. Flanagan, J.G. et al. (1991) Cell 64:1025.
  14. Martin, F.H. et al. (1990) Cell 63:203.
  15. Lemmon, M.A. et al. (1997) J. Biol. Chem. 272:6311.
  16. Kanellakis, P. et al. (2006) Cardiovasc. Res. 70:117.
Long Name
Stem Cell Factor
Entrez Gene IDs
4254 (Human); 17311 (Mouse); 60427 (Rat); 403507 (Canine); 493937 (Feline)
Alternate Names
c-kit Ligand; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; KIT ligand; Kitl; KITLG; KL-1; Mast cell growth factor; MGF; MGFSHEP7; SCF; SCFStem cell factor; SFc-Kit ligand; SHEP7; SLF; steel factor

Citations for Recombinant Mouse SCF Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

135 Citations: Showing 1 - 10
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  1. Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium
    Authors: T Fukushima, Y Tanaka, FK Hamey, CH Chang, T Oki, S Asada, Y Hayashi, T Fujino, T Yonezawa, R Takeda, KC Kawabata, T Fukuyama, T Umemoto, K Takubo, H Takizawa, S Goyama, Y Ishihama, H Honda, B Göttgens, T Kitamura
    Cell Rep, 2019;29(12):4144-4158.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  2. Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling
    Authors: ML Capitano, N Mor-Vaknin, AK Saha, S Cooper, M Legendre, H Guo, R Contreras-, F Kappes, MA Sartor, CT Lee, X Huang, DM Markovitz, HE Broxmeyer
    J. Clin. Invest., 2019;130(0):2555-2570.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Group 2 innate lymphoid cells (ILC2) are regulated by stem cell factor during chronic asthmatic disease
    Authors: W Fonseca, AJ Rasky, C Ptaschinsk, SH Morris, SKK Best, M Phillips, CA Malinczak, NW Lukacs
    Mucosal Immunol, 2019;12(2):445-456.
  4. Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis
    Authors: N Maio, KS Kim, G Holmes-Ham, A Singh, TA Rouault
    Haematologica, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse
    Authors: AD Senft, EK Bikoff, EJ Robertson, I Costello
    Nat Commun, 2019;10(1):1089.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  6. The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance
    Authors: N Vannini, V Campos, M Girotra, V Trachsel, S Rojas-Sutt, J Tratwal, S Ragusa, E Stefanidis, D Ryu, PY Rainer, G Nikitin, S Giger, TY Li, A Semilietof, A Oggier, Y Yersin, L Tauzin, E Pirinen, WC Cheng, J Ratajczak, C Canto, M Ehrbar, F Sizzano, TV Petrova, D Vanhecke, L Zhang, P Romero, A Nahimana, S Cherix, MA Duchosal, PC Ho, B Deplancke, G Coukos, J Auwerx, MP Lutolf, O Naveiras
    Cell Stem Cell, 2019;24(3):405-418.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome
    Authors: F Ribezzo, IAM Snoeren, S Ziegler, J Stoelben, PA Olofsen, A Henic, MV Ferreira, S Chen, USA Stalmann, G Buesche, RM Hoogenboez, R Kramann, U Platzbecke, MHGP Raaijmaker, BL Ebert, RK Schneider
    Leukemia, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Establishment of an erythroid progenitor cell line capable of enucleation achieved with an inducible c-Myc vector
    Authors: S Mayers, PD Moço, T Maqbool, PN Silva, DM Kilkenny, J Audet
    BMC Biotechnol., 2019;19(1):21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis
    Authors: SK Nandakumar, SK McFarland, LM Mateyka, CA Lareau, JC Ulirsch, LS Ludwig, G Agarwal, JM Engreitz, B Przychodze, M McConkey, GS Cowley, JG Doench, JP Maciejewsk, BL Ebert, DE Root, VG Sankaran
    Elife, 2019;8(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation
    Authors: MJ Delás, BT Jackson, T Kovacevic, S Vangelisti, E Munera Mar, SA Wild, EM Stork, N Erard, SRV Knott, GJ Hannon
    Cell Rep, 2019;27(3):719-729.e6.
    Species: Mouse
    Sample Types: cell culture
    Applications: cell culture media
  11. Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC
    Authors: C Li, L Dong, R Su, Y Bi, Y Qing, X Deng, Y Zhou, C Hu, M Yu, H Huang, X Jiang, X Li, X He, D Zou, C Shen, L Han, M Sun, J Skibbe, K Ferchen, X Qin, H Weng, H Huang, C Song, J Chen, J Jin
    Haematologica, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Secretion of Mast Cell Inflammatory Mediators Is Enhanced by CADM1-Dependent Adhesion to Sensory Neurons
    Authors: R Magadmi, J Meszaros, ZA Damanhouri, EP Seward
    Front Cell Neurosci, 2019;13(0):262.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Adult stem cell deficits drive Slc29a3 disorders in mice
    Authors: S Nair, AM Strohecker, AK Persaud, B Bissa, S Muruganand, C McElroy, R Pathak, M Williams, R Raj, A Kaddoumi, A Sparreboom, AM Beedle, R Govindaraj
    Nat Commun, 2019;10(1):2943.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  14. Hto, Tritiated Amino Acid Exposure and External Exposure Induce Differential Effects on Hematopoiesis and Iron Metabolism
    Authors: JM Bertho, D Kereselidz, L Manens, C Culeux, V Magneron, J Surette, M Blimkie, L Bertrand, H Wyatt, M Souidi, I Dublineau, N Priest, JR Jourdain
    Sci Rep, 2019;9(1):19919.
    Species: Mouse
    Sample Types: Plasma
    Applications: Multiplex Standard
  15. In vivo selection with lentiviral expression of Bcl2T69A/S70A/S87Amutant in hematopoietic stem cell-transplanted mice
    Authors: YY Wang, S Ma, Q Chen, D Jiao, Y Yang
    Gene Ther., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  16. An activating mutation of interferon regulatory factor 4 (IRF4) in adult T cell leukemia
    Authors: MA Cherian, S Olson, H Sundaramoo, K Cates, X Cheng, J Harding, A Martens, GA Challen, M Tyagi, L Ratner, D Rauch
    J. Biol. Chem., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs
    Authors: P Wünsche, ESP Eckert, T Holland-Le, A Paruzynski, A Hotz-Wagen, R Fronza, T Rath, I Gil-Farina, M Schmidt, C von Kalle, C Klein, CR Ball, F Herbst, H Glimm
    Cell Stem Cell, 2018;23(1):132-146.e9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Mast cells are essential intermediaries in regulating IL-33/ST2 signaling for an immune network favorable to mucosal healing in experimentally inflamed colons
    Authors: Z He, J Song, J Hua, M Yang, Y Ma, T Yu, J Feng, B Liu, X Wang, Y Li, J Li
    Cell Death Dis, 2018;9(12):1173.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  19. Global H3.3 dynamic deposition defines its bimodal role in cell fate transition
    Authors: HT Fang, CA El Farran, QR Xing, LF Zhang, H Li, B Lim, YH Loh
    Nat Commun, 2018;9(1):1537.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. A single cell hematopoietic landscape resolves eight lineage trajectories and defects in Kit mutant mice
    Authors: JS Dahlin, FK Hamey, B Pijuan-Sal, M Shepherd, WWY Lau, S Nestorowa, C Weinreb, S Wolock, R Hannah, E Diamanti, DG Kent, B Göttgens, NK Wilson
    Blood, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation
    Authors: R Nagase, D Inoue, A Pastore, T Fujino, HA Hou, N Yamasaki, S Goyama, M Saika, A Kanai, Y Sera, S Horikawa, Y Ota, S Asada, Y Hayashi, KC Kawabata, R Takeda, HF Tien, H Honda, O Abdel-Waha, T Kitamura
    J. Exp. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Kbtbd2 inhibits the cytotoxic activity of immortalized NK cells through down-regulating mTOR signaling in a mouse hepatocellular carcinoma model
    Authors: K Dai, Y Huang, Z Chen, X Sun, L Yang, Y Jiang
    Eur. J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Wild-type Kras expands and exhausts hematopoietic stem cells
    Authors: JP Sasine, HA Himburg, CM Termini, M Roos, E Tran, L Zhao, J Kan, M Li, Y Zhang, SC de Barros, DS Rao, CM Counter, JP Chute
    JCI Insight, 2018;3(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Wild-type Kras expands and exhausts hematopoietic stem cells
    Authors: JP Sasine, HA Himburg, CM Termini, M Roos, E Tran, L Zhao, J Kan, M Li, Y Zhang, SC de Barros, DS Rao, CM Counter, JP Chute
    JCI Insight, 2018;3(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming
    Authors: AD Senft, I Costello, HW King, AW Mould, EK Bikoff, EJ Robertson
    Cell Rep, 2018;24(8):1977-1985.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice
    Authors: X Jin, X He, X Cao, P Xu, Y Xing, S Sui, L Wang, J Meng, W Lu, R Cui, H Ni, M Zhao
    Haematologica, 2018;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  27. Botulinum toxin blocks mast cells and prevents rosacea like inflammation
    Authors: JE Choi, T Werbel, Z Wang, CC Wu, TL Yaksh, A Di Nardo
    J. Dermatol. Sci., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Brief Exposure of Skin to Near-Infrared Laser Modulates Mast Cell Function and Augments the Immune Response
    Authors: Y Kimizuka, W Katagiri, JJ Locascio, A Shigeta, Y Sasaki, M Shibata, K Morse, RF Sîrbulescu, M Miyatake, P Reeves, M Suematsu, J Gelfand, T Brauns, MC Poznansky, K Tsukada, S Kashiwagi
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types:
    Applications: Cell Culture
  29. Syntaxin 3, but not Syntaxin 4, is required for mast cell regulated exocytosis, where it plays a primary role mediating compound exocytosis
    Authors: E Sanchez, EA Gonzalez, DS Moreno, RA Cardenas, MA Ramos, AJ Davalos, J Manllo, AI Rodarte, Y Petrova, DC Moreira, MA Chavez, A Tortoriell, A Lara, BA Gutierrez, AR Burns, R Heidelberg, R Adachi
    J. Biol. Chem., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Mutation-specific signaling profiles and kinase inhibitor sensitivities of juvenile myelomonocytic leukemia revealed by induced pluripotent stem cells
    Authors: SK Tasian, JA Casas, D Posocco, S Gandre-Bab, AL Gagne, G Liang, ML Loh, MJ Weiss, DL French, ST Chou
    Leukemia, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis
    Authors: H Tokuo, J Bhawan, LM Coluccio
    Sci Rep, 2018;8(1):10449.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Bone Marrow-Derived Cells Trafficking to the Oviduct: Effect of Ischemia-Reperfusion Injury
    Authors: C Sahin, R Mamillapal, HS Taylor
    Reprod Sci, 2018;0(0):1933719118770.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  33. The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia
    Authors: H Wang, L Bei, CA Shah, W Huang, LC Platanias, EA Eklund
    Oncogene, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Tracking embryonic hematopoietic stem cells to the bone marrow: nanoparticle options to evaluate transplantation efficiency
    Authors: SK Sweeney, GS Manzar, N Zavazava, JG Assouline
    Stem Cell Res Ther, 2018;9(1):204.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Combinations of antioxidants and/or of epigenetic enzyme inhibitors allow for enhanced collection of mouse bone marrow hematopoietic stem cells in ambient air
    Authors: Q Cai, M Capitano, X Huang, B Guo, S Cooper, HE Broxmeyer
    Blood Cells Mol. Dis., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Interleukin-9 promotes early mast cell-mediated expulsion of Strongyloides ratti but is dispensable for generation of protective memory
    Authors: M Reitz, W Hartmann, N Rüdiger, Z Orinska, ML Brunn, M Breloer
    Sci Rep, 2018;8(1):8636.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. An unexpected protective role of low affinity allergen-specific IgG via the inhibitory receptor Fc?RIIb
    Authors: M Bachmann, M Vogel, L Zha, F Leoratti, L He, MO Mohsen, F Storni, M Cragg,
    J. Allergy Clin. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  38. A Study and Review of Effects of Botulinum Toxins on Mast Cell Dependent and Independent Pruritus
    Authors: R Ramachandr, MJ Marino, S Paul, Z Wang, NL Mascarenha, S Pellett, EA Johnson, A DiNardo, TL Yaksh
    Toxins (Basel), 2018;10(4):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation
  39. Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle regulated exocytosis in mast cells
    Authors: BA Gutierrez, MA Chavez, AI Rodarte, M Ramos, A Dominguez, Y Petrova, AJ Davalos, RM Costa, R Elizondo, MJ Tuvim, BF Dickey, AR Burns, R Heidelberg, R Adachi
    J. Biol. Chem., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation
    Authors: Y Heshmati, S Kharazi, G Türköz, D Chang, E Kamali Dol, J Boström, A Krstic, T Boukoura, E Wagner, N Kadri, R Månsson, M Altun, H Qian, J Walfridsso
    Sci Rep, 2018;8(1):11202.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Loss of the Liver X Receptors Disrupts the Balance of Hematopoietic Populations, With Detrimental Effects on Endothelial Progenitor Cells
    Authors: A Rasheed, R Tsai, CL Cummins
    J Am Heart Assoc, 2018;7(10):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Mesenchymal Cell Reprogramming in Experimental MPLW515L Mouse Model of Myelofibrosis
    Authors: Y Han, L Yue, M Wei, X Ren, Z Shao, L Zhang, RL Levine, PK Epling-Bur
    PLoS ONE, 2017;12(1):e0166014.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Radiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1)
    Authors: KZ Oben, BW Gachuki, SS Alhakeem, MK McKenna, Y Liang, DK St Clair, VM Rangnekar, S Bondada
    PLoS ONE, 2017;12(1):e0169767.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin
    Authors: NJ Huang, N Pishesha, J Mukherjee, S Zhang, R Deshycka, V Sudaryo, M Dong, CB Shoemaker, HF Lodish
    Nat Commun, 2017;8(1):423.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. In vitro expansion of mouse primordial germ cell-like cells recapitulates an epigenetic blank slate
    Authors: H Ohta, K Kurimoto, I Okamoto, T Nakamura, Y Yabuta, H Miyauchi, T Yamamoto, Y Okuno, M Hagiwara, K Shirane, H Sasaki, M Saitou
    EMBO J., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment
    Authors: B Guo, X Huang, S Cooper, HE Broxmeyer
    Nat. Med, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Hematopoietic pannexin 1 function is critical for neuropathic pain
    Authors: JL Weaver, S Arandjelov, G Brown, S K Mendu, M S Schappe, MW Buckley, YH Chiu, S Shu, JK Kim, J Chung, J Krupa, V Jevtovic-T, BN Desai, KS Ravichandr, DA Bayliss
    Sci Rep, 2017;7(0):42550.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Interaction of primary mast cells with Borrelia burgdorferi (sensu stricto): role in transmission and dissemination in C57BL/6 mice
    Authors: Q Bernard, Z Wang, A Di Nardo, N Boulanger
    Parasit Vectors, 2017;10(1):313.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors
    Authors: A Itoh-Nakad, M Matsumoto, H Kato, J Sasaki, Y Uehara, Y Sato, R Ebina-Shib, M Morooka, R Funayama, K Nakayama, K Ochiai, A Muto, K Igarashi
    Cell Rep, 2017;18(10):2401-2414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Lentiviral Fluorescent Genetic Barcoding for Multiplex Fate Tracking of Leukemic Cells
    Authors: T Maetzig, J Ruschmann, L Sanchez Mi, CK Lai, N von Krosig, RK Humphries
    Mol Ther Methods Clin Dev, 2017;6(0):54-65.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia
    Authors: Y Chen, K Anastassia, A Kranz, AF Stewart, K Arndt, C Waskow, A Yokoyama, K Jones, T Neff, Y Lee, P Ernst
    Cancer Cell, 2017;31(6):755-770.e6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Metabolic Reprogramming, Autophagy, and Reactive Oxygen Species Are Necessary for Primordial Germ Cell Reprogramming into Pluripotency
    Authors: D Sainz de l, A Moratilla, V Aparicio, C Lorca, Y Alcaina, D Martín, MP De Miguel
    Oxid Med Cell Longev, 2017;2017(0):4745252.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1
    Authors: S Shukla, MA Langley, J Singh, JM Edgar, M Mohtashami, JC Zúñiga-Pfl, PW Zandstra
    Nat. Methods, 2017;14(5):531-538.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Anti-KIT Monoclonal Antibody Treatment Enhances the Anti-Tumor Activity of Immune Checkpoint Inhibitors by Reversing Tumor-Induced Immunosuppression
    Authors: AJ Garton, S Seibel, L Lopresti-M, L Crew, N Janson, S Mandiyan, ES Trombetta, S Pankratz, TM LaVallee, R Gedrich
    Mol. Cancer Ther, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34(+) Cells for Correction of Fabry Disease
    Authors: J Huang, A Khan, BC Au, DL Barber, L López-Vásq, NL Prokopishy, M Boutin, M Rothe, JW Rip, M Abaoui, MS Nagree, S Dworski, A Schambach, A Keating, ML West, J Klassen, PV Turner, S Sirrs, CA Rupar, C Auray-Blai, R Foley, JA Medin
    Mol Ther Methods Clin Dev, 2017;5(0):241-258.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation
    Authors: Y Zhao, K Wu, C Nguyen, G Smbatyan, E Melendez, Y Higuchi, Y Chen, M Kahn
    PLoS ONE, 2017;12(5):e0177245.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia
    Authors: X Jiang, C Hu, K Ferchen, J Nie, X Cui, CH Chen, L Cheng, Z Zuo, W Seibel, C He, Y Tang, JR Skibbe, M Wunderlich, WC Reinhold, L Dong, C Shen, S Arnovitz, B Ulrich, J Lu, H Weng, R Su, H Huang, Y Wang, C Li, X Qin, J Mulloy, Y Zheng, J Diao, J Jin, C Li, PP Liu, C He, Y Chen, J Chen
    Nat Commun, 2017;8(1):2099.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors
    Nat Commun, 2016;7(0):13396.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency
    Stem Cell Reports, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  60. In�Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells
    Cell Rep, 2016;17(10):2789-2804.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins
    Nat. Med., 2016;22(6):672-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Chronic myelogenous leukemia initiating cells require Polycomb group protein EZH2
    Cancer Discov, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells
    Authors: L Dimitrov, D Pedersen, KH Ching, H Yi, EJ Collarini, S Izquierdo, MC van de Lav, PA Leighton
    PLoS ONE, 2016;11(4):e0154303.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Reprogramming M�ller glia via in vivo cell fusion regenerates murine photoreceptors
    J Clin Invest, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  65. The non-canonical Wnt receptor Ryk regulates hematopoietic stem cell repopulation in part by controlling proliferation and apoptosis
    Cell Death Dis, 2016;7(11):e2479.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis
    Oncogene, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Generation of chickens expressing Cre recombinase
    Authors: PA Leighton, D Pedersen, K Ching, EJ Collarini, S Izquierdo, R Jacob, MC van de Lav
    Transgenic Res, 2016;0(0):.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Systemic Ablation of MMP9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL-6 Expression in the Bone Marrow
    Mol Cancer Res, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  69. miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia
    Authors: X Jiang, C Hu, S Arnovitz, J Bugno, M Yu, Z Zuo, P Chen, H Huang, B Ulrich, S Gurbuxani, H Weng, J Strong, Y Wang, Y Li, J Salat, S Li, AG Elkahloun, Y Yang, MB Neilly, RA Larson, MM Le Beau, T Herold, SK Bohlander, PP Liu, J Zhang, Z Li, C He, J Jin, Hon
    Nat Commun, 2016;7(0):11452.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms
    Nat. Med, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  71. Loss of Sfrp2 in the Niche Amplifies Stress-Induced Cellular Responses, and Impairs the in Vivo Regeneration of the Hematopoietic Stem Cell Pool
    Authors: Franziska Ruf
    Stem Cells, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis
    PLoS ONE, 2016;11(5):e0154630.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Arid3b Is Critical for B Lymphocyte Development
    PLoS ONE, 2016;11(8):e0161468.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Prevention of Lethal Murine Hypophosphatasia by Neonatal Ex Vivo Gene Therapy Using Lentivirally Transduced Bone Marrow Cells
    Authors: O Iijima, K Miyake, A Watanabe, N Miyake, T Igarashi, C Kanokoda, A Nakamura-T, H Kinoshita, T Noguchi, S Abe, S Narisawa, JL Millán, T Okada, T Shimada
    Hum. Gene Ther, 2015;26(12):801-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes.
    Authors: Huan J, Hornick N, Goloviznina N, Kamimae-Lanning A, David L, Wilmarth P, Mori T, Chevillet J, Narla A, Roberts C, Loriaux M, Chang B, Kurre P
    Leukemia, 2015;29(12):2285-95.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Grb10 is involved in BCR-ABL-positive leukemia in mice.
    Authors: Illert, A L, Albers, C, Kreutmair, S, Leischner, H, Peschel, C, Miething, C, Duyster, J
    Leukemia, 2015;29(4):858-68.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  77. Inhibition of Donor-Reactive CD8+ T Cell Responses by Selective CD28 Blockade Is Independent of Reduced ICOS Expression.
    Authors: Liu D, Suchard S, Nadler S, Ford M
    PLoS ONE, 2015;10(6):e0130490.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Hepatocyte Nuclear Factor 1A Is a Cell-Intrinsic Transcription Factor Required for B Cell Differentiation and Development in Mice.
    Authors: von Wnuck Lipinski K, Sattler K, Peters S, Weske S, Keul P, Klump H, Heusch G, Gothert J, Levkau B
    J Immunol, 2015;196(4):1655-65.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1.
    Authors: Wang H, Bei L, Shah C, Hu L, Eklund E
    J Immunol, 2015;194(11):5375-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Targeted 25-hydroxyvitamin D3 1alpha-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice.
    Authors: Li B, Baylink D, Walter M, Lau K, Meng X, Wang J, Cherkas A, Tang X, Qin X
    Mol Ther, 2015;23(2):339-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  81. In Vitro Spermatogenesis in Explanted Adult Mouse Testis Tissues.
    Authors: Sato T, Katagiri K, Kojima K, Komeya M, Yao M, Ogawa T
    PLoS ONE, 2015;10(6):e0130171.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  82. Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice.
    Authors: Bender M, Giannini S, Grozovsky R, Jonsson T, Christensen H, Pluthero F, Ko A, Mullally A, Kahr W, Hoffmeister K, Falet H
    Blood, 2015;125(6):1014-24.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  83. CD252 regulates mast cell mediated, CD1d-restricted NKT-cell activation in mice.
    Authors: Gonzalez Roldan N, Orinska Z, Ewers H, Bulfone-Paus S
    Eur J Immunol, 2015;46(2):432-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy.
    Authors: Schumacher A, Denecke B, Braunschweig T, Stahlschmidt J, Ziegler S, Brandenburg L, Stope M, Martincuks A, Vogt M, Gortz D, Camporeale A, Poli V, Muller-Newen G, Brummendorf T, Ziegler P
    J Hematol Oncol, 2015;8(0):64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Identification and distribution of developing innate lymphoid cells in the fetal mouse intestine.
    Authors: Bando J, Liang H, Locksley R
    Nat Immunol, 2015;16(2):153-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1.
    Authors: Fukuda, S, Hoggatt, J, Singh, P, Abe, M, Speth, J M, Hu, P, Conway, E M, Nucifora, G, Yamaguchi, S, Pelus, L M
    Leukemia, 2015;29(2):433-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  87. In vivo regulation of erythropoiesis by chemically inducible dimerization of the erythropoietin receptor intracellular domain.
    Authors: Suzuki, Norio, Mukai, Harumi Y, Yamamoto, Masayuki
    PLoS ONE, 2015;10(3):e0119442.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  88. FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets.
    Authors: Begonja A, Pluthero F, Suphamungmee W, Giannini S, Christensen H, Leung R, Lo R, Nakamura F, Lehman W, Plomann M, Hoffmeister K, Kahr W, Hartwig J, Falet H
    Blood, 2015;126(1):80-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  89. The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy.
    Authors: Wang L, Rao T, Rowe R, Nguyen P, Sullivan J, Pearson D, Doulatov S, Wu L, Lindsley R, Zhu H, DeAngelo D, Daley G, Wagers A
    Leukemia, 2015;29(6):1320-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Aurora kinase A is required for hematopoiesis but is dispensable for murine megakaryocyte endomitosis and differentiation.
    Authors: Goldenson B, Kirsammer G, Stankiewicz M, Wen Q, Crispino J
    Blood, 2015;125(13):2141-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence.
    Authors: Kim P, Nakano H, Das P, Chen M, Rowe R, Chou S, Ross S, Sakamoto K, Zon L, Schlaeger T, Orkin S, Nakano A, Daley G
    J Exp Med, 2015;212(5):633-48.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  92. CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: redefinition of murine common myeloid progenitor.
    Authors: Miyawaki K, Arinobu Y, Iwasaki H, Kohno K, Tsuzuki H, Iino T, Shima T, Kikushige Y, Takenaka K, Miyamoto T, Akashi K
    Stem Cells, 2015;33(3):976-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells.
    Authors: Nakahara F, Kitaura J, Uchida T, Nishida C, Togami K, Inoue D, Matsukawa T, Kagiyama Y, Enomoto Y, Kawabata K, Chen-Yi L, Komeno Y, Izawa K, Oki T, Nagae G, Harada Y, Harada H, Otsu M, Aburatani H, Heissig B, Hattori K, Kitamura T
    Blood, 2014;123(25):3932-42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Critical role for NAD glycohydrolase in regulation of erythropoiesis by hematopoietic stem cells through control of intracellular NAD content.
    Authors: Nam T, Park K, Shawl A, Kim B, Han M, Kim Y, Moss J, Kim U
    J Biol Chem, 2014;289(23):16362-73.
    Species: Rabbit
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Sphingosine kinase 2 promotes acute lymphoblastic leukemia by enhancing MYC expression.
    Authors: Wallington-Beddoe C, Powell J, Tong D, Pitson S, Bradstock K, Bendall L
    Cancer Res, 2014;74(10):2803-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  96. Embryonic stem cell-derived haematopoietic progenitor cells down-regulate the CD3 xi chain on T cells, abrogating alloreactive T cells.
    Authors: Kim E, Miyake B, Aggarwal M, Voetlause R, Griffith M, Zavazava N
    Immunology, 2014;142(3):421-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis.
    Authors: Boettcher S, Gerosa R, Radpour R, Bauer J, Ampenberger F, Heikenwalder M, Kopf M, Manz M
    Blood, 2014;124(9):1393-403.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Establishment of a mast cell line, NCL-2, without Kit mutation, derived from NC mouse bone marrow.
    Authors: Hiragun T, Yanase Y, Okabe T, Hiragun M, Kawai M, Hide M
    FEBS Open Bio, 2014;4(0):342-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells.
    Authors: Luyten A, Zang C, Liu X, Shivdasani R
    Genes Dev, 2014;28(16):1827-39.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  100. The DNA binding property of PML/RARA but not the integrity of PML nuclear bodies is indispensable for leukemic transformation.
    Authors: Liu X, Yuan H, Peres L, Chen S, Chen Z, de The H, Zhou J, Zhu J
    PLoS ONE, 2014;9(8):e104906.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Ectopic TLX1 expression accelerates malignancies in mice deficient in DNA-PK.
    Authors: Krutikov K, Zheng Y, Chesney A, Huang X, Vaags A, Evdokimova V, Hough M, Chen E
    PLoS ONE, 2014;9(2):e89649.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Leukotriene B4 amplifies eosinophil accumulation in response to nematodes.
    Authors: Patnode M, Bando J, Krummel M, Locksley R, Rosen S
    J Exp Med, 2014;211(7):1281-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.
    Authors: Roderick, Justine, Tesell, Jessica, Shultz, Leonard, Brehm, Michael, Greiner, Dale L, Harris, Marian H, Silverman, Lewis B, Sallan, Stephen, Gutierrez, Alejandr, Look, A Thomas, Qi, Jun, Bradner, James E, Kelliher, Michelle
    Blood, 2014;123(7):1040-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Computational promoter modeling identifies the modes of transcriptional regulation in hematopoietic stem cells.
    Authors: Park S, Umemoto T, Saito-Adachi M, Shiratsuchi Y, Yamato M, Nakai K
    PLoS ONE, 2014;9(4):e93853.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity.
    Authors: Nagareddy P, Kraakman M, Masters S, Stirzaker R, Gorman D, Grant R, Dragoljevic D, Hong E, Abdel-Latif A, Smyth S, Choi S, Korner J, Bornfeldt K, Fisher E, Dixit V, Tall A, Goldberg I, Murphy A
    Cell Metab, 2014;19(5):821-35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia.
    Authors: Zimdahl, Bryan, Ito, Takahiro, Blevins, Allen, Bajaj, Jeevisha, Konuma, Takaaki, Weeks, Joi, Koechlein, Claire S, Kwon, Hyog You, Arami, Omead, Rizzieri, David, Broome, H Elizab, Chuah, Charles, Oehler, Vivian G, Sasik, Roman, Hardiman, Gary, Reya, Tannisht
    Nat Genet, 2014;46(3):245-52.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  107. Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism.
    Authors: Reber L, Daubeuf F, Pejler G, Abrink M, Frossard N
    J Immunol, 2014;192(4):1847-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.
    Authors: Bettini M, Blanchfield L, Castellaw A, Zhang Q, Nakayama M, Smeltzer M, Zhang H, Hogquist K, Evavold B, Vignali D
    J Immunol, 2014;193(2):571-9.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  109. BMP4 is required for the initial expression of MITF in melanocyte precursor differentiation from embryonic stem cells.
    Authors: Yang J, Wang J, Pan L, Li H, Rao C, Zhang X, Niu G, Qu J, Hou L
    Exp Cell Res, 2014;320(1):54-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Modulation of Ras signaling alters the toxicity of hydroquinone, a benzene metabolite and component of cigarette smoke.
    Authors: North, Matthew, Shuga, Joe, Fromowitz, Michele, Loguinov, Alexandr, Shannon, Kevin, Zhang, Luoping, Smith, Martyn T, Vulpe, Chris D
    BMC Cancer, 2014;14(0):6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm.
    Authors: Zhang H, Nieves J, Fraser S, Isern J, Douvaras P, Papatsenko D, D'Souza S, Lemischka I, Dyer M, Baron M
    Stem Cells, 2014;32(1):191-203.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Gene therapy delivery of myelin oligodendrocyte glycoprotein (MOG) via hematopoietic stem cell transfer induces MOG-specific B cell deletion.
    Authors: Chung, Jie-Yu, Figgett, William, Fairfax, Kirsten, Bernard, Claude, Chan, James, Toh, Ban-Hock, Mackay, Fabienne, Alderuccio, Frank
    J Immunol, 2014;192(6):2593-601.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  113. The critical role of mast cell-derived hypoxia-inducible factor-1alpha in human and mice melanoma growth.
    Authors: Jeong H, Oh H, Nam S, Han N, Kim Y, Kim J, Lee S, Kim M, Moon P, Kim H, Oh H
    Int J Cancer, 2013;132(11):2492-501.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  114. Identification of transcription factors for lineage-specific ESC differentiation.
    Authors: Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, Schlessinger D, Ko M
    Stem Cell Reports, 2013;1(6):545-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  115. Induction of a hemogenic program in mouse fibroblasts.
    Authors: Pereira C, Chang B, Qiu J, Niu X, Papatsenko D, Hendry C, Clark N, Nomura-Kitabayashi A, Kovacic J, Ma'ayan A, Schaniel C, Lemischka I, Moore K
    Cell Stem Cell, 2013;13(2):205-18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  116. IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation.
    Authors: Sandig H, Jobbings C, Roldan N, Whittingham-Dowd J, Orinska Z, Takeuchi O, Akira S, Bulfone-Paus S
    Eur J Immunol, 2013;43(4):979-88.
  117. Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells.
    Authors: Kinzfogl J, Hangoc G, Broxmeyer HE
    Blood, 2011;118(3):565-75.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment.
    Authors: Cook BD, Liu S, Evans T
    Blood, 2011;117(24):6489-97.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  119. A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst.
    Authors: Artus J, Panthier JJ, Hadjantonakis AK
    Development, 2010;137(20):3361-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  120. Role of stem cell factor and bone marrow-derived fibroblasts in airway remodeling.
    Authors: Dolgachev VA, Ullenbruch MR, Lukacs NW, Phan SH
    Am. J. Pathol., 2009;174(2):390-400.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  121. An activating and inhibitory signal from an inhibitory receptor LMIR3/CLM-1: LMIR3 augments lipopolysaccharide response through association with FcRgamma in mast cells.
    Authors: Izawa K, Kitaura J, Yamanishi Y, Matsuoka T, Kaitani A, Sugiuchi M, Takahashi M, Maehara A, Enomoto Y, Oki T, Takai T, Kitamura T
    J. Immunol., 2009;183(2):925-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  122. Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.
    Authors: Kerenyi MA, Grebien F, Gehart H, Schifrer M, Artaker M, Kovacic B, Beug H, Moriggl R, Mullner EW
    Blood, 2008;112(9):3878-88.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells.
    Authors: Huynh H, Iizuka S, Kaba M, Kirak O, Zheng J, Lodish HF, Zhang CC
    Stem Cells, 2008;26(6):1628-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  124. The lineage-c-Kit+Sca-1+ cell response to Escherichia coli bacteremia in Balb/c mice.
    Authors: Zhang P, Nelson S, Bagby GJ, Siggins R, Shellito JE, Welsh DA
    Stem Cells, 2008;26(7):1778-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  125. IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis.
    Authors: Yamaguchi Y, Fujio K, Shoda H, Okamoto A, Tsuno NH, Takahashi K, Yamamoto K
    J. Immunol., 2007;179(10):7128-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Nociceptive tuning by stem cell factor/c-Kit signaling.
    Authors: Milenkovic N, Frahm C, Gassmann M, Griffel C, Erdmann B, Birchmeier C, Lewin GR, Garratt AN
    Neuron, 2007;56(5):893-906.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  127. Commonly dysregulated genes in murine APL cells.
    Authors: Yuan W, Payton JE, Holt MS, Link DC, Watson MA, DiPersio JF, Ley TJ
    Blood, 2007;109(3):961-70.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  128. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells.
    Authors: Rajesh&lt;/LastName&gt;&lt;ForeNam D&lt;/Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF
    Stem Cells, 2007;25(2):490-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  129. c-kit delineates a distinct domain of progenitors in the developing kidney.
    Authors: Schmidt-Ott KM, Chen X, Paragas N, Levinson RS, Mendelsohn CL, Barasch J
    Dev. Biol., 2006;299(1):238-49.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  130. Cytokine-containing gelfoam implants at a postsurgical tumor excision site to stimulate local immune reactivity.
    Authors: Young MR
    Int. J. Cancer, 2006;119(1):133-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  131. Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo.
    Authors: Braun BS, Archard JA, Van Ziffle JA, Tuveson DA, Jacks TE, Shannon K
    Blood, 2006;108(6):2041-4.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity.
    Authors: Yilmaz OH, Kiel MJ, Morrison SJ
    Blood, 2005;107(3):924-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Immortalization of mouse germ line stem cells.
    Authors: Hofmann MC, Braydich-Stolle L, Dettin L, Johnson E, Dym M
    Stem Cells, 2005;23(2):200-10.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  134. The IL-6 family cytokines, interleukin-6, interleukin-11, oncostatin M, and leukemia inhibitory factor, enhance mast cell growth through fibroblast-dependent pathway in mice.
    Authors: Gyotoku E, Morita E, Kameyoshi Y, Hiragun T, Yamamoto S, Hide M
    Arch. Dermatol. Res., 2001;293(10):508-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Stem cell factor improves the repopulating ability of primitive hematopoietic stem cells after sublethal irradiation (and, to a lesser extent) after bone marrow transplantation in mice.
    Authors: Gardner RV, 48657, Oliver P, Astle CM
    Involvement of ?-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum, 1998;16(2):112-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo

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