Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

CoraFluor 1

Antibody Source

Polyclonal Sheep IgG
View all Reg1 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse Reg1
Gln22-Gly165
Accession # P43137

Specificity

Detects mouse Reg1 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse (rm) Reg2 is observed and less than 5% cross-reactivity with rmReg3A, recombinant human (rh) Reg1B, rhReg4, recombinant rat (rr) Reg3 and rrReg2 is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

CoraFluor(TM) 1, amine reactive

CoraFluor(TM) 1, thiol reactive

For more information, please see our CoraFluor(TM) TR-FRET technology flyer.

Scientific Data Images for Reg1 Antibody [CoraFluor™ 1]

Reg1 Antibody [CoraFluor™ 1]

Product Feature: CoraFluor Probes for TR-FRET

CoraFluor™ 1, amine reactive (Catalog:7920) and CoraFluor™ 2, amine reactive (Catalog # 7950) are terbium-based probes that have been developed for use as TR-FRET donors. They emit wavelengths compatible with commonly used fluorescent acceptor dyes such as BODIPY® (or BDY) and Janelia Fluor® dyes, FITC (Catalog # 5440), TMR and Cyanine 5 (Catalog # 5436). CoraFluor™ fluorescence is brighter and more stable in biological media than existing TR-FRET donors, leading to enhanced sensitivity and improved data generation. CoraFluor™ 1 exhibits excitation upon exposure to a 337 nm UV laser.

Applications for Reg1 Antibody [CoraFluor™ 1]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Reg1

REG1, also known as Lithostathine-1-alpha, is a secreted 19kDa 166 amino acid protein. The gene is a type I subclass member of the Reg gene family and is associated with pancreas and brain regeneration. Current research on REG1 is being conducted in relation to cystic fibrosis, nephropathy, cerebral atherosclerosis, hereditary pancreatitis, pancreatitis, celiac disease, hepatocellular carcinoma, Alzheimer's disease and Down syndrome. REG1 has been linked to the secretion, cell proliferation, coagulation and cell growth pathways where it interacts with REG3A.

Long Name

Regenerating Islet-derived 1

Alternate Names

ICRF, Islet cells regeneration factor, Islet of Langerhans regenerating protein, lithostathine-1-alpha, Pancreatic stone protein, pancreatic stone protein, secretory, Pancreatic thread protein, protein-X, PSPregenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic threadprotein), PSPS1REG-1-alpha, PSPSMGC12447, PTPP19, regenerating islet-derived 1 alpha, Regenerating islet-derived protein 1-alpha, Regenerating protein I alpha, REGlithostathine 1 alpha

Gene Symbol

Reg1

Additional Reg1 Products

Product Documents for Reg1 Antibody [CoraFluor™ 1]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Reg1 Antibody [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

C-type Lectin Family
Diabetes

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