Renin Antibody (OTI2F10)

Novus Biologicals | Catalog # NBP2-45552

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI2F10
View all Renin Primary Antibodies »

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 131-406 of human REN(NP_000528) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

42.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Renin Antibody (OTI2F10)

Western Blot: Renin Antibody (OTI2F10) [NBP2-45552]

Western Blot: Renin Antibody (OTI2F10) [NBP2-45552]

Western Blot: Renin Antibody (2F10) [NBP2-45552] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Renin.
Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (2F10) [NBP2-45552] - Analysis of Human tonsil tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (2F10) [NBP2-45552] - Analysis of Adenocarcinoma of Human breast tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (2F10) [NBP2-45552] - Analysis of Human Kidney tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (2F10) [NBP2-45552] - Analysis of Human liver tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (2F10) [NBP2-45552] - Analysis of Human lung tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (2F10) [NBP2-45552] - Analysis of Adenocarcinoma of Human ovary tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (2F10) [NBP2-45552] - Analysis of Human pancreas tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (2F10) [NBP2-45552] - Analysis of Carcinoma of Human prostate tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (OTI2F10) [NBP2-45552]

Immunohistochemistry: Renin Antibody (2F10) [NBP2-45552] - Analysis of Human lymphoma tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)

Applications for Renin Antibody (OTI2F10)

Application
Recommended Usage

Immunohistochemistry

1:150

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Renin

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.

Alternate Names

Angiotensinogenase, REN

Gene Symbol

REN

Additional Renin Products

Product Documents for Renin Antibody (OTI2F10)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Renin Antibody (OTI2F10)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Renin Antibody (OTI2F10)

Customer Reviews for Renin Antibody (OTI2F10)

There are currently no reviews for this product. Be the first to review Renin Antibody (OTI2F10) and earn rewards!

Have you used Renin Antibody (OTI2F10)?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies