RENT1/UPF1/hUPF1 Antibody

Name: RENT1/UPF1/hUPF1 Antibody
Brand: Novus Biologicals
SKU: NBP2-16905
Price: 489 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-16905

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

View all RENT1/UPF1 Primary Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human RENT1/UPF1/hUPF1. The exact sequence is proprietary.

Localization

Cytoplasm; P-body

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

123 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for RENT1/UPF1/hUPF1 Antibody

Western Blot: RENT1/UPF1/hUPF1 Antibody [NBP2-16905]

Western Blot: hUPF1 Antibody [NBP2-16905] - Sample (30 ug of whole cell lysate) A: A431 5% SDS PAGE gel, diluted at 1:500.

Immunohistochemistry-Paraffin: RENT1/UPF1/hUPF1 Antibody [NBP2-16905]

Immunohistochemistry-Paraffin: hUPF1 Antibody [NBP2-16905] - Immunohistochemical analysis of paraffin-embedded Colon ca, using antibody at 1:500 dilution.

Applications for RENT1/UPF1/hUPF1 Antibody

Application

Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: RENT1/UPF1

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq]

Long Name

Regulator of Nonsense Transcripts 1

Alternate Names

NORF1, UPF1

Gene Symbol

UPF1

UniProt

Q92900 (Human)

Additional RENT1/UPF1 Products

Product Documents for RENT1/UPF1/hUPF1 Antibody

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Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for RENT1/UPF1/hUPF1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information go to www.P65Warnings.ca.gov.

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