(RS)-MCPG disodium salt

Tocris Bioscience | Catalog # 3696

Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336)
Tocris Bioscience

Key Product Details

Description

Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336)
View all Group I mGluR Antagonists »

Product Description

(RS)-MCPG disodium salt is a sodium salt of (RS)-MCPG, a non-selective group I/group II metabotropic glutamate receptor antagonist.

S-enantiomer also available.

Product Specifications for (RS)-MCPG disodium salt

Molecular Weight

253.16

Formula

C10H9NNa2O4

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(RS)-α-Methyl-4-carboxyphenylglycine disodium salt

PubChem ID

90488871

InChI Key

YGOTXTUQJLFNHB-UHFFFAOYSA-L

SMILES

[Na+].[Na+].CC(N)(C([O-])=O)C1=CC=C(C=C1)C([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 25.32 100

Preparing Stock Solutions for (RS)-MCPG disodium salt

The following data is based on the product molecular weight 253.16.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.95 mL 19.75 mL 39.50 mL
5 mM 0.79 mL 3.95 mL 7.90 mL
10 mM 0.40 mL 1.98 mL 3.95 mL
50 mM 0.08 mL 0.40 mL 0.79 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for (RS)-MCPG disodium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (RS)-MCPG disodium salt

For research use only

Citations for (RS)-MCPG disodium salt

Customer Reviews for (RS)-MCPG disodium salt (1)

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  • Suppression of mGluR action triggered by glutamate application
    Name: Sergiy Sylantyev
    Species: Human
    Cell Line/Tissue: Stem cell - derived neurons
    Verified Customer | Posted 10/15/2020
    (RS)-MCPG disodium salt was in use to prevent contamination of NMDA-receptor – generated response to prolonged application of glutamate with (possible) impact from metabotropic glutamate receptors (mGluRs). APV, applied after glutamate, fully suppressed NMDA-receptor response, thus suggesting no input from mGluRs (see illustration). MCPG disodium salt works as expected; the effects and time interval for response development are same with those of (RS)-MCPG, but the salt is much easier soluble.
    (RS)-MCPG disodium salt 3696

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