Sal 003

Catalog # Availability Size / Price Qty
3657/10
3657/50
Sal 003 | CAS No. 1164470-53-4 | Protein Ser/Thr Phosphatase Inhibitors
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Description: Cell-permeable inhibitor of eIF2α dephosphorylation

Chemical Name: 3--Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide

Purity: ≥99%

Product Details
Citations (2)
Reviews

Biological Activity

Cell-permeable inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF2α). Analog of salubrinal (Cat. No. 2347) with improved aqueous solubility. Shown to prevent the induction of hippocampal long-term potentiation (LTP) and memory formation (LTM) in mice.

Technical Data

M.Wt:
463.21
Formula:
C18H15Cl4N3OS
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
1164470-53-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for Sal 003

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2 Citations: Showing 1 - 2

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