12 results for "Protein Ser/Thr Phosphatase Inhibitors" in Products
Protein Ser/Thr Phosphatase Inhibitors
Protein Ser/Thr phosphatases are a group of enzymes that catalyze the removal of phosphate groups from serine and/or threonine residues by the hydrolysis of phosphoric acid monoesters. They directly oppose the actions of kinases and phosphorylases and therefore play an integral role in many signal transduction pathways.
There are two groups of serine/threonine phosphatases: phosphoprotein phosphatases (e.g. PP1, calcineurin), which are sensitive to okadaic acid; and metallo-phosphatases (e.g. ...
Calcineurin inhibitor
| Alternate Names: | Ciclosporin A |
| Purity: | ≥98% |
Selective inhibitor of eIF2α dephosphorylation
| Chemical Name: | 3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide |
| Purity: | ≥98% |
Potent calcineurin inhibitor; immunosuppressant
| Alternate Names: | Tacrolimus,Fujimycin |
| Chemical Name: | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)tetrone |
| Purity: | ≥98% |
Protein phosphatase 1 and 2A inhibitor
| Chemical Name: | N-[(3S)-[4-(1E)-3-[(2R,3R,4R,7S,8S,9R)-2-[(1S,3S,4S,5R,7E,9E,11E,13Z)-14-Cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradecatetraenyl]-9-hydroxy-4,4,8-trimethyl-3-(phosphonooxy)-1,6-dioxaspiro[4.5]dec-7-yl]-1-propenyl]-2-oxazoly]butyl]-4-deoxy-4-(dimethylamino)-5-O-methyl-L-ribonamide |
| Purity: | ≥90% |
Inhibitor of calcineurin-mediated NFAT activation
| Alternate Names: | VIVIT peptide |
| Purity: | ≥95% |
Inhibitor of protein phosphatase 2C (PP2C)
| Chemical Name: | 13-Methyl-[1,3]-benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium chloride |
| Purity: | ≥97% |
Cell-permeable inhibitor of eIF2α dephosphorylation
| Chemical Name: | 3--Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide |
| Purity: | ≥98% |
Potent and selective allosteric inhibitor of Wip1 phosphatase
| Chemical Name: | 5-[[(5-Chloro-2-methyl-3-pyridinyl)amino]methyl]-N-[(1S)-1-(cyclopentylmethyl)-2-(cycloprpylamino)-2-oxoethyl]-2-thiophenecarboxamide |
| Purity: | ≥98% |
Inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1
| Chemical Name: | (2E)-2-[(2-Chlorophenyl)methylene]-hydrazinecarboximidamide carbonic acid salt |
| Purity: | ≥98% |
Cell permeable NFAT inhibitor
| Alternate Names: | 11R-VIVIT |
| Purity: | ≥95% |
DUSP6 and DUSP1 inhibitor
| Chemical Name: | 3-(Cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1H-inden-1-one |
| Purity: | ≥98% |
Protein phosphatase 1 and 2A inhibitor
| Chemical Name: | 9,10-Deepithio-9,10-didehydroacanthifolicin ammonium salt |
| Purity: | ≥98% |
