Q: Has it been tested whether the two antobodies anti-M protein from SARS-CoV cross-react with that of SARS-CoV-2? The references are 56569SS and NBP1-28852.

A: Sars Membrane Protein Antibody NB100-56569 expected cross reactivity with SARS-CoV-2 based on immunogen sequence homology: 93%. Sars Membrane Protein Antibody (2H2C4) NBP1-28852 expected cross reactivity with SARS-CoV-2 based on immunogen sequence homology: 88%

Sars Membrane Protein Antibody (2H2C4)

Novus Biologicals | Catalog # NBP1-28852

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

SARS-CoV

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ Clone # 2H2C4

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Product Specifications

Immunogen

Purified recombinant fragment of SARS-m protein expressed in E. Coli.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: COVID-19 (88%)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Scientific Data Images for Sars Membrane Protein Antibody (2H2C4)

Western Blot: Sars Membrane Protein Antibody (2H2C4)Azide and BSA Free [NBP1-28852]

Western Blot: Sars M Antibody (2H2C4) [NBP1-28852] - Western blot analysis using SARS-mpm mouse mAb against SARS-mpm recombinant protein.

Applications for Sars Membrane Protein Antibody (2H2C4)

Application

Recommended Usage

ELISA

1:10000

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Subclonal supernatant

Preservative

No Preservative

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Sars Membrane Protein

SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The complete sequence of the SARS virus release the coronavirus contains 25 open reading frames. SARS-m is a membrane (M) protein which plays a the key player in virion assembly. One of its functions is to mediate the incorporation of the spikes into the viral envelope.

Alternate Names

E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein, SARS coronavirus M protein, SARS coronavirus Membrane protein, SARS CoV, SARS CoV M glycoprotein, SARS CoV Matrix protein, Sars M, Sars Matrix Protein, SARSCoV, SARS-CoV M protein, SARS-CoV Membrane protein, Severe acute respiratory syndrome

Additional Sars Membrane Protein Products

Product Documents for Sars Membrane Protein Antibody (2H2C4)

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Certificate of Analysis

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Product Specific Notices for Sars Membrane Protein Antibody (2H2C4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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