Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all SHANK1 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to an N terminal portion of human SHANK1 protein (between residues 110-160) [UniProt Q9Y566]

Reactivity Notes

Reacts with human and rat Shank1a. Does not react with mouse Shank1a.

Localization

Cytoplasmic, Cell junction, Postsynaptic density of neuronal cells.

Marker

TGN Marker

Specificity

Reacts with residues [ERLLREYPQSFEKGV] of the N terminus of the rat Shank1a protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SHANK1 Antibody - BSA Free

Western Blot: SHANK1 AntibodyBSA Free [NB300-166]

Western Blot: SHANK1 AntibodyBSA Free [NB300-166]

Western Blot: SHANK1 Antibody [NB300-166] - Western blot analysis of SHANK1 in rat brain lysate using NB300-166 at 1:500 dilution.

Applications for SHANK1 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500 -1:1000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SHANK1

Shank is a novel family of postsynaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.

Alternate Names

SH3 and multiple ankyrin repeat domains 1, SH3 and multiple ankyrin repeat domains protein 1, Shank1, Somatostatin receptor-interacting protein, SSTR-interacting protein, SSTRIPSPANK-1, synamon

Entrez Gene IDs

243961 (Mouse); 78957 (Rat)

Gene Symbol

SHANK1

Additional SHANK1 Products

Product Documents for SHANK1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for SHANK1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for SHANK1 Antibody - BSA Free

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