Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

HRP

Antibody Source

Polyclonal Rabbit IgG
View all SHANK1 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to an N terminal portion of human SHANK1 protein (between residues 110-160) [UniProt Q9Y566]

Reactivity Notes

Reacts with human and rat Shank1a. Does not react with mouse Shank1a.

Localization

Cytoplasmic, Cell junction, Postsynaptic density of neuronal cells.

Marker

TGN Marker

Specificity

Reacts with residues [ERLLREYPQSFEKGV] of the N terminus of the rat Shank1a protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for SHANK1 Antibody [HRP]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: SHANK1

Shank is a novel family of postsynaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.

Alternate Names

SH3 and multiple ankyrin repeat domains 1, SH3 and multiple ankyrin repeat domains protein 1, Shank1, Somatostatin receptor-interacting protein, SSTR-interacting protein, SSTRIPSPANK-1, synamon

Gene Symbol

SHANK1

Additional SHANK1 Products

Product Documents for SHANK1 Antibody [HRP]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for SHANK1 Antibody [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

No product specific FAQs exist for this product.

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