SLC45A3/Prostein Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-89629

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PKYRGDTGGASSEDSLMTSFLPGPKPGAPFPNGHVGAGGSGLLPPPPALCGASACDVSVRVVVGEP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (85%)

Marker

Prostate Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SLC45A3/Prostein Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: SLC45A3/Prostein Antibody [NBP1-89629]

Immunocytochemistry/ Immunofluorescence: SLC45A3/Prostein Antibody [NBP1-89629]

Immunocytochemistry/Immunofluorescence: SLC45A3/Prostein Antibody [NBP1-89629] - Staining of human cell line U-2 OS shows localization to vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629] - Staining of human liver, placenta, prostate and testis using Anti-SLC45A3 antibody NBP1-89629 (A) shows similar protein distribution across tissues to independent antibody NBP1-89630 (B).
SLC45A3/Prostein Antibody - BSA Free Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody - BSA Free [NBP1-89629]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody - BSA Free [NBP1-89629]

Analysis in human prostate and liver tissues using NBP1-89629 antibody. Corresponding SLC45A3 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629] - Staining of human prostate shows strong granular cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629] - Staining of human placenta shows no positivity in trophoblastic cells as expected.
Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629]

Immunohistochemistry-Paraffin: SLC45A3/Prostein Antibody [NBP1-89629] - Staining of human testis shows no positivity in cells in seminiferous ducts as expected.

Applications for SLC45A3/Prostein Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC45A3/Prostein

Prostein is a novel prostate-specific protein expressed in normal and malignant prostate tissues. This protein appears to be a type IIIa plasma membrane protein with a cleavable signal peptide and 11 transmembrane-spanning regions. Prostein expression is androgen responsive since treatment of LNCaP cells with androgen up-regulates prostein message and protein expression levels. Thus, prostein is a prostate-specific marker whose detection and quantitation may be useful in diagnosing and monitoring prostate cancer.

Long Name

Solute Carrier Family 45 Member 3

Alternate Names

IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, Prostein, PRST, S45A3

Gene Symbol

SLC45A3

Additional SLC45A3/Prostein Products

Product Documents for SLC45A3/Prostein Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SLC45A3/Prostein Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

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Protocols

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FAQs

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