STAT5a/b [p Tyr694, p Tyr699] Antibody (1247C) [Biotin]

Name: STAT5a/b [p Tyr694, p Tyr699] Antibody (1247C) [Biotin]
Brand: Novus Biologicals
SKU: FAB41901B
Price: 579 USD
Availability: InStock

Novus Biologicals | Catalog # FAB41901B

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Applications
Flow Cytometry
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Intracellular Staining by Flow Cytometry, CyTOF-ready

Label

Biotin

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 1247C

View all STAT5a/b Primary Antibodies »

Product Specifications

Immunogen

Phosphopeptide containing human STAT5b Y699 site (amino acid sequence of this peptide is identical to a corresponding region of human STAT5a containing Y694)
Accession # P51692

Specificity

Detects human STAT5a/b when phosphorylated at Y964/Y699 in direct ELISAs and Western blots.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for STAT5a/b [p Tyr694, p Tyr699] Antibody (1247C) [Biotin]

Application

Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Intracellular Staining by Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

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Advanced Features

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Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: STAT5a/b

Signal transduction and activator of transcription 5 (STAT5) is a member of the Jak/STAT signal transduction pathway and is activated by a variety of cytokines (IL22, IL6, IFN-α). STAT5 has two isoforms (A and B) that share 93% amino acid identity and bind the DNA consensus site TTCN3GAA. STAT5 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, translocates to the nucleus and activates transcription of specific genes. STAT5 is involved in a wide array of biological processes ranging from regulating apoptosis to adult mammary gland proliferation, differentiation and survival.

Long Name

Signal Transducer and Activator of Transcription 5b

Alternate Names

MGF, STAT5, STAT5A signal transducer and activator of transcription 5A

Additional STAT5a/b Products

Product Documents for STAT5a/b [p Tyr694, p Tyr699] Antibody (1247C) [Biotin]

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Product Specific Notices for STAT5a/b [p Tyr694, p Tyr699] Antibody (1247C) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.