Catalog # Availability Size / Price Qty

Save Up to 40% on RUO Reagents with BIOSPRING24 (See Details)

Sulfasalazine | CAS No. 599-79-1 | NFkB/IkB Inhibitors
1 Image
Description: Inhibitor of NF-κB activation; also inhibits SXC and folate transporter 1

Chemical Name: 5-[[4-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid

Purity: ≥97%

Product Details
Citations (3)

Biological Activity

Sulfasalazine is an inhibitor of NF-κB activation. Inhibits in vitro growth of the human pancreatic cancer cell lines MIA PaCa-2 and PANC-1, and induces apoptosis in glioblastoma cell lines. Also inhibits the cystine-glutamate antiporter, system Xc (SXC). Inhibitor of folate transporter 1 (SLC19A1); inhibits cellular uptake of Methotrexate (Cat. No. 1230) and cyclic dinucleotides, including 2',3'-cGAMP (Cat.No. 5945). Anti-inflammatory. Induces ferroptosis.

Technical Data

Soluble to 100 mM in DMSO
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

⚠ WARNING: This product can expose you to chemicals including Sulfasalazine (Salicylazosulfapyridine), which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to

Citations for Sulfasalazine

The citations listed below are publications that use Tocris products. Selected citations for Sulfasalazine include:

3 Citations: Showing 1 - 3


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Sulfasalazine

There are currently no reviews for this product. Be the first to review Sulfasalazine and earn rewards!

Have you used Sulfasalazine?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.