Sulfasalazine

Catalog # Availability Size / Price Qty
4935/50
Cat.No. 4935 - Sulfasalazine | C18H14N4O5S | CAS No. 599-79-1
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Description: Inhibitor of NF-κB activation; also inhibits SXC

Chemical Name: 5-[[4-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Inhibitor of NF-κB activation. Inhibits in vitro growth of the human pancreatic cancer cell lines MIA PaCa-2 and PANC-1, and induces apoptosis in glioblastoma cell lines. Also inhibits the cystine-glutamate antiporter, system Xc (SXC). Anti-inflammatory. Induces ferroptosis.

Technical Data

M.Wt:
398.39
Formula:
C18H14N4O5S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
599-79-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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⚠ WARNING: This product can expose you to chemicals including Sulfasalazine (Salicylazosulfapyridine), which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Citation for Sulfasalazine

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