SYK Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-86178

Novus Biologicals
100% Guarantee

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all SYK Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPKPGHRKSSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SYK Antibody - BSA Free

Immunohistochemistry-Paraffin: SYK Antibody [NBP1-86178]

Immunohistochemistry-Paraffin: SYK Antibody [NBP1-86178]

Immunohistochemistry-Paraffin: SYK Antibody [NBP1-86178] - Staining of human tonsil shows high expression.
Immunohistochemistry-Paraffin: SYK Antibody [NBP1-86178]

Immunohistochemistry-Paraffin: SYK Antibody [NBP1-86178]

Immunohistochemistry-Paraffin: SYK Antibody [NBP1-86178] - Staining of human liver shows low expression as expected.
Immunohistochemistry-Paraffin: SYK Antibody [NBP1-86178]

Immunohistochemistry-Paraffin: SYK Antibody [NBP1-86178]

Immunohistochemistry-Paraffin: SYK Antibody [NBP1-86178] - Staining in human tonsil and liver tissues using anti-SYK antibody. Corresponding SYK RNA-seq data are presented for the same tissues.
SYK Antibody - BSA Free Immunohistochemistry-Paraffin: SYK Antibody - BSA Free [NBP1-86178]

Immunohistochemistry-Paraffin: SYK Antibody - BSA Free [NBP1-86178]

Staining of human skeletal muscle shows no cytoplasmic positivity in myocytes as expected.
SYK Antibody - BSA Free Immunohistochemistry-Paraffin: SYK Antibody - BSA Free [NBP1-86178]

Immunohistochemistry-Paraffin: SYK Antibody - BSA Free [NBP1-86178]

Staining of human small intestine shows moderate cytoplasmic positivity in glandular cells.
SYK Antibody - BSA Free Immunohistochemistry-Paraffin: SYK Antibody - BSA Free [NBP1-86178]

Immunohistochemistry-Paraffin: SYK Antibody - BSA Free [NBP1-86178]

Staining of human lung shows strong cytoplasmic positivity in macrophages.
SYK Antibody - BSA Free Immunohistochemistry-Paraffin: SYK Antibody - BSA Free [NBP1-86178]

Immunohistochemistry-Paraffin: SYK Antibody - BSA Free [NBP1-86178]

Staining of human tonsil shows strong cytoplasmic positivity in germinal center cells.
SYK Antibody - BSA Free Immunohistochemistry-Paraffin: SYK Antibody - BSA Free [NBP1-86178]

Immunohistochemistry-Paraffin: SYK Antibody - BSA Free [NBP1-86178]

Immunohistochemistry analysis in human tonsil and skeletal muscle tissues using HPA001384 antibody. Corresponding SYK RNA-seq data are presented for the same tissues.

Applications for SYK Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SYK

Syk (72 kDa) is a non-receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions.

Long Name

Spleen Tyrosine Kinase

Alternate Names

DKFZp313N1010, EC 2.7.10, EC 2.7.10.2, FLJ25043, spleen tyrosine kinaseFLJ37489, tyrosine-protein kinase SYK

Gene Symbol

SYK

Additional SYK Products

Product Documents for SYK Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for SYK Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for SYK Antibody - BSA Free

There are currently no reviews for this product. Be the first to review SYK Antibody - BSA Free and earn rewards!

Have you used SYK Antibody - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies