TACI/TNFRSF13B/CVID Antibody (8F10) - Azide and BSA Free

Novus Biologicals | Catalog # NBP1-97618

Novus Biologicals
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Key Product Details

Species Reactivity

Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # 8F10

Format

Azide and BSA Free
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Product Specifications

Immunogen

Rat RBL cells expressing mouse TACI.

Reactivity Notes

Recognizes Mouse TACI.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Scientific Data Images for TACI/TNFRSF13B/CVID Antibody (8F10) - Azide and BSA Free

Flow Cytometry: BAFF/BLyS/TNFSF13B Antibody (8F10) - Azide and BSA Free [NBP1-97618]

Flow Cytometry: BAFF/BLyS/TNFSF13B Antibody (8F10) - Azide and BSA Free [NBP1-97618]

Flow Cytometry: BAFF/BLyS/TNFSF13B Antibody (8F10) [NBP1-97618] - HEK 293T cells were mock transfected (thin line) or transfected with an expression plasmid enabling surface expression of the extracellular domain of mouse TACI (thick line). Cells (5 x 10^5) were incubated on ice for 30 min in 50 ul FACS buffer (PBS, 5% Fetal calf serum, 0.02% azide) containing 1ug/ml of rat anti-mTACI 8F10 MAb. After washing in FACS buffer, R-PE-conjugated antibody to rat IgG was added. Cells were incubated on ice for 30 min, washed and then analyzed by flow cytometry.

Applications for TACI/TNFRSF13B/CVID Antibody (8F10) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500
Application Notes
Functional Application (inhibition).

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Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TACI/TNFRSF13B

TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17.

Long Name

Transmembrane Activator and CAML Interactor/Tumor Necrosis Factor Receptor Superfamily Member 13B

Alternate Names

CD267, CVID, TNFRSF13B

Gene Symbol

TNFRSF13B

Additional TACI/TNFRSF13B Products

Product Documents for TACI/TNFRSF13B/CVID Antibody (8F10) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for TACI/TNFRSF13B/CVID Antibody (8F10) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for TACI/TNFRSF13B/CVID Antibody (8F10) - Azide and BSA Free

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Protocols

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