TC 2559 difumarate

Catalog # Availability Size / Price Qty
2737/10
2737/50
TC 2559 difumarate | Nicotinic (a4b2) Receptor Agonists
1 Image
Description: Selective α4β2 nAChR partial agonist

Chemical Name: 4-(5-ethoxy-3-pyridinyl)-N-methyl-(3E)-3-buten-1-amine difumarate

Purity: ≥98%

Product Details
Citations (2)
Supplemental Products
Reviews

Biological Activity

Subtype-selective partial agonist for α4β2 nicotinic acetylcholine receptors (EC50 values are 0.18, 12.5, 14.0, > 30, > 100 and > 100 μM for α4β2, α4β4, α2β4, α3β4, α3β2 and α7 receptor subtypes respectively). Displays selectivity for (α4)2(β2)3 receptor stoichiometry and enhanced CNS-PNS selectivity ratio. Attenuates scopolamine-induced cognitive deficits in a step-through passive avoidance task.

Technical Data

M.Wt:
438.43
Formula:
C12H18N2O.2C4H4O4
Solubility:
Soluble to 100 mM in water
Purity:
≥98%
Storage:
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for TC 2559 difumarate

The citations listed below are publications that use Tocris products. Selected citations for TC 2559 difumarate include:

2 Citations: Showing 1 - 2

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

VersaClone cDNA Plasmids

Reviews for TC 2559 difumarate

There are currently no reviews for this product. Be the first to review TC 2559 difumarate and earn rewards!

Have you used TC 2559 difumarate?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.