Tec Antibody (S09-6E7)

Name: Tec Antibody (S09-6E7)
Brand: Novus Biologicals
SKU: NBP3-19784
Price: 559 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-19784

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S09-6E7 expressed in HEK293

View all Tec Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human Tec (Uniprot # P42680)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Tec Antibody (S09-6E7)

Western Blot: Tec Antibody (S09-6E7) [NBP3-19784]

Western Blot: Tec Antibody (S09-6E7) [NBP3-19784] - Western blot detection of Tec in K562 cell lysates using NBP3-19784 (1:1000 diluted). Predicted band size: 74kDa. Observed band size: 58-75kDa.

Immunocytochemistry/Immunofluorescence: Tec Antibody (S09-6E7) [NBP3-19784] -

Immunocytochemistry/Immunofluorescence: Tec Antibody (S09-6E7) [NBP3-19784] - Immunocytochemistry of Tec (green) in Hela cells using NBP3-19784 at dilution 1/50, and DAPI (blue)

Applications for Tec Antibody (S09-6E7)

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

1/20-1/100

Western Blot

1/2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tec

Tec is a member of the Tec family of non-receptor protein-tyrosine kinase (PTK) which also includes Btk, emtk/itk/Tsk, Rlk/Txx and Bmx (1). Tec is composed of a pleckstrin domain (PH), an SH3 and SH2 domain, a catalytic kinase domain and a Tec homology domain (TH) (2). Tec's TH domain interacts with the SH3 domain of Grb2, Src family PTKs (Fyn, Lyn, and Hck), Vav, and c-Kit. Tec is mostly expressed in hematopoietic cells. Tec's SH3 domain interacts with DC28 and has been shown to phosphorylate p62dok, CD28 substrate (3). Tec can phosphorylate Jak kinase in hematopoietic cells (4) and can also be phosphorylated by Src member Lyn on multiple tyrosine residues (5).

Long Name

Translocated in Extraskeletal Chondrosarcoma Protein Tyrosine Kinase

Alternate Names

PSCTK4

Gene Symbol

TEC

Additional Tec Products

Product Documents for Tec Antibody (S09-6E7)

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Certificate of Analysis

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Product Specific Notices for Tec Antibody (S09-6E7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Intracellular Kinases

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