Key Product Details

Species Reactivity

Non-species specific

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Rabbit IgG
View all TetR Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to an N-terminal portion of Escherichia coli TetR protein (between residues 1-50) [UniProt P04483]

Localization

TetR peptide conserved in all strains of gram negative bacteria

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for TetR Antibody [Biotin]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TetR

Tetracycline repressor protein class B from transposon Tn10 (TetR) is a transcription regulator that represses the tetracycline resistance element. The affinity for the tetracycline resistance gene (TetA) promoter operator sites are reduced by the binding of tetracycline to TetR. TetR also binds to DNA on its N-terminal region due to its helix-turn-helix structure (HTH tetR-type DNA-binding domain). The tetracycline resistance element repressed by TetR is responsible for the maintenance of genetic antibiotic resistance traits in strains of Escherichia coli (E.coli). These traits confer an advantage in selection to E. coli expressing this antibiotic resistance (PMID: 18039823).

Alternate Names

pSC101 tetR, Tet Repressor, Tet Repressor Protein, TetR, tetracycline repressor protein

Additional TetR Products

Product Documents for TetR Antibody [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for TetR Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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