TGR5/GPBAR1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-49376

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all TGR5/GPBAR1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LGDQRYTAPWRAAAQRCLQGLWGRASRD

Reactivity Notes

Mouse (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TGR5/GPBAR1 Antibody - BSA Free

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376] - Staining of human placenta shows high expression.
Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376] - Staining in human placenta and pancreas tissues using anti-GPBAR1 antibody. Corresponding GPBAR1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376] - Analysis in human gallbladder and skeletal muscle tissues. Corresponding TGR5/GPBAR1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376] - Staining of human cerebral cortex shows no positivity in neurons as expected.
Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376]

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NBP2-49376] - Staining of human gallbladder shows moderate membranous positivity in glandular cells.

Applications for TGR5/GPBAR1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TGR5/GPBAR1

TGR5, also called GPBAR1, M-BAR, or BG37 or is a G-protein coupled receptor superfamily member that is a widely expressed cell surface receptor for bile acids. On macrophages, bile acid engagement of TGR5/GPBAR1 suppresses phagocytosis and other functions. Extracellular portions of human TGR5/GPBAR1 show approximately 75% amino acid identity with corresponding regions of mouse TGR5/GPBAR1.

Long Name

Bile Acid Receptor TGR5

Alternate Names

BG37, GPBA, GPBAR1, GPCR19, GPR131, M-BAR

Gene Symbol

GPBAR1

Additional TGR5/GPBAR1 Products

Product Documents for TGR5/GPBAR1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for TGR5/GPBAR1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Nutrition and Appetite

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Protocols

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