Tocrifluor T1117

Catalog # Availability Size / Price Qty
2540/100U
Cat.No. 2540 - Tocrifluor T1117 | C56H53Cl2N7O5 | CAS No. 1186195-59-4
1 Image
Description: Fluorescent cannabinoid ligand; fluorescent form of AM 251 (Cat. No. 1117)

Chemical Name: N-(Piperidin-1-yl)-5-(4-(4-(3-(5-carboxamidotetramethylrhodaminyl)propyl))phenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

Purity: ≥95%

Product Details
Citations (3)
Supplemental Products
Reviews

Biological Activity

Fluorescent form of AM 251. AM 251 conjugated with 5-carboxytetramethylrhodamine (5-TAMRA) that fluoresces at 543 nm excitation (590 nm emission). Displays GPR55 binding activity.

View more information regarding Tocrifluor T1117.

Technical Data

M.Wt:
974.97
Formula:
C56H53Cl2N7O5
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
1186195-59-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

  1. Beyond radio-displacement techniques for identification of CB1 ligands: the first application of a fluorescence-quenching assay.
    Bruno et al.
    Sci.Rep., 2014;4:3757
  2. Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses.
    Sylantyev et al.
    Proc.Natl.Acad.Sci.U.S.A., 2013;110:5193
  3. Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries.
    Daly et al.
    Br.J.Pharmacol., 2010;159:787
  4. Visualisation of vascular cannabinoid receptors and their potential interaction with α1-adrenergic receptors.
    Daly et al.
    Vascular and Smooth Muscle Phys.Soc. Symposium, 2008;

Product Datasheets

or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for Tocrifluor T1117

The citations listed below are publications that use Tocris products. Selected citations for Tocrifluor T1117 include:

3 Citations: Showing 1 - 3

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Tocrifluor T1117

There are currently no reviews for this product. Be the first to review Tocrifluor T1117 and earn rewards!

Have you used Tocrifluor T1117?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.