Tocrifluor T1117
Tocris Bioscience | Catalog # 2540
Key Product Details
Description
Wavelength
Product Description
Tocrifluor T1117 is a fluorescent form of AM 251. AM 251 conjugated with 5-carboxytetramethylrhodamine (5-TAMRA) that fluoresces at 543 nm excitation (590 nm emission). Displays GPR55 binding activity. Wavelengths are compatible with use as an acceptor dye in TR-FRET assays, together with the CoraFluor™ 1 (Cat. No. 7920) TR-FRET donor.
View more information regarding Tocrifluor T1117.
Optical Data
| λabs | 543 nm |
| λem | 590 nm |
| Application | Fluorescence Microscopy, Confocal Microscopy |
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Product Specifications for Tocrifluor T1117
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 9.75 | 10 |
Preparing Stock Solutions for Tocrifluor T1117
The following data is based on the product molecular weight 974.97.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10.26 mL | 51.28 mL | 102.57 mL |
| 0.5 mM | 2.05 mL | 10.26 mL | 20.51 mL |
| 1 mM | 1.03 mL | 5.13 mL | 10.26 mL |
| 5 mM | 0.21 mL | 1.03 mL | 2.05 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.
- Bruno Beyond radio-displacement techniques for identification of CB1 ligands: the first application of a fluorescence-quenching assay. Sci.Rep. 2014 PMID: 24441508
- Daly Visualisation of vascular cannabinoid receptors and their potential interaction with α1-adrenergic receptors. Vascular and Smooth Muscle Phys.Soc. Symposium
- Sylantyev Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses. Proc.Natl.Acad.Sci.U.S.A. 2013 PMID: 23472002
- Daly Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries. Br.J.Pharmacol. 2010 PMID: 20136833
Product Documents for Tocrifluor T1117
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Tocrifluor T1117
For research use only
Related Research Areas
Citations for Tocrifluor T1117
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