Fluorescent form of AM 251
(Cat. No. 1117). AM 251 conjugated with 5-carboxytetramethylrhodamine (5-TAMRA) that fluoresces at 543 nm excitation (590 nm emission). Displays GPR55 binding activity.
Soluble to 10 mM in DMSO
Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Beyond radio-displacement techniques for identification of CB1 ligands: the first application of a fluorescence-quenching assay.
Bruno et al.
Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries.
Daly et al.
Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses.
Sylantyev et al.
Visualisation of vascular cannabinoid receptors and their potential interaction with α1-adrenergic receptors.
Daly et al.
Vascular and Smooth Muscle Phys.Soc. Symposium, 2008;
The citations listed below are publications that use Tocris products. Selected citations for Tocrifluor T1117 include:
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