TOMM34 Antibody (Tomm34-4.1) - BSA Free

Novus Biologicals | Catalog # NBP3-11704

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # Tomm34-4.1

Format

BSA Free
View all TOMM34 Primary Antibodies »

Product Specifications

Immunogen

Recombinant human Tomm34

Specificity

The mouse monoclonal antibody Tomm34-4.1 recognizes an epitope within TPR2 domain of human TOMM34 protein.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for TOMM34 Antibody (Tomm34-4.1) - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Phosphate buffered saline (PBS), pH 7.4

Format

BSA Free

Preservative

15mM Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: TOMM34

TOMM34 (Translocase of the outer mitochondrial membrane 34) is an additional component of the cellular chaperone system involved in protein folding. As the name suggests, TOMM34 was initially identified as being involved in mitochondrial protein processing. Subsequent studies have shown that TOMM34 interacts with both Hsp70 and Hsp90 and modifies their protein folding activities. In cancer, high levels of TOMM34 have been reported in bladder, colorectal and breast cancers compared to their normal tissue counterparts. In these cancers, TOMM34 promotes colorectal cancer cell growth and is a biomarker of poor outcome in early invasive breast cancer and bladder cancer. As a tumour-associated protein, TOMM34 peptide vaccination is under investigation as a therapeutic option for colorectal cancer, with significant TOMM34 cytotoxic T-lymphocyte (CTL) response observed.

Alternate Names

hTom34, HTOM34P, mitochondrial import receptor subunit TOM34, outer mitochondrial membrane translocase (34kD), TOM34, Translocase of outer membrane 34 kDa subunit, translocase of outer mitochondrial membrane 34, URCC3

Gene Symbol

TOMM34

Additional TOMM34 Products

Product Documents for TOMM34 Antibody (Tomm34-4.1) - BSA Free

Certificate of Analysis

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Product Specific Notices for TOMM34 Antibody (Tomm34-4.1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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