TrkC [p Tyr820] Antibody

Novus Biologicals | Catalog # NBP1-03448

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all TrkC Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide to phospho Y820 of human TrkC (Trk-C, NTRK3, NT-3 growth factor receptor, GP145-TrkC) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and mouse.

Modification

p Tyr820

Localization

subcellular location: membrane; single-pass type i membrane protein.; tissue specificity: widely expressed, mainly in the nervous tissue. the isoform b is expressed in a relatively large amount in the adult brain comparatively to fetal brain.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TrkC [p Tyr820] Antibody

Western Blot: TrkC [p Tyr820] Antibody [NBP1-03448]

Western Blot: TrkC [p Tyr820] Antibody [NBP1-03448]

Western Blot: TrkC [p Tyr820] Antibody [NBP1-03448] - Rat brain lysate using Rabbit antibody to phospho Y820 TrkC: whole serum at 1:1000 dilution incubated overnight at 4 degrees C. A single band will be detected. Pre-absorption of the antibody with the immunising peptide completely abolishes the detected band.

Applications for TrkC [p Tyr820] Antibody

Application
Recommended Usage

Immunohistochemistry

1:300-1:3000

Immunohistochemistry-Paraffin

1:300-1:3000

Western Blot

1:300-1:3000

Formulation, Preparation, and Storage

Purification

Unpurified

Reconstitution

Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the sample size is provided in reconstituted format.

Formulation

Lyophilized from whole antisera

Preservative

No Preservative

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: TrkC

Receptor for neurotrophin-3 (nt-3). this is a tyrosine-protein kinase receptor. known substrates for the trk receptors are shc1, pi-3 kinase, and plcg1. the different isoforms do not have identical signaling properties.

Long Name

Neurotrophic Tyrosine Kinase Receptor C

Alternate Names

NTRK3

Entrez Gene IDs

4916 (Human); 18213 (Mouse); 29613 (Rat)

Gene Symbol

NTRK3

UniProt

Q16288

Additional TrkC Products

Product Documents for TrkC [p Tyr820] Antibody

Certificate of Analysis

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Product Specific Notices for TrkC [p Tyr820] Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Receptor Tyrosine Kinases (RTKs)

Citations for TrkC [p Tyr820] Antibody

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Protocols

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FAQs

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