TWEAK R/TNFRSF12 Antibody (ITEM-4) - Low Endotoxin

Novus Biologicals | Catalog # NBP3-09099

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # ITEM-4

Format

Low Endotoxin
View all TWEAK R/TNFRSF12 Primary Antibodies »

Product Specifications

Immunogen

human TWEAK R/TNFRSF12-transfected P815 cells

Specificity

The mouse monoclonal antibody ITEM-4 recognizes an extracellular epitope of CD266 / TWEAK R, a TNFR superfamily receptor for CD255 / TWEAK, a TNF-like weak inducer of apoptosis.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Endotoxin Level

Endotoxin level is less than 0.01 EU/ug of the protein, as determined by the LAL test.

Scientific Data Images for TWEAK R/TNFRSF12 Antibody (ITEM-4) - Low Endotoxin

Flow Cytometry: TWEAK R/TNFRSF12 Antibody (ITEM-4) - Low Endotoxin, Azide and BSA Free [NBP3-09099]

Flow Cytometry: TWEAK R/TNFRSF12 Antibody (ITEM-4) - Low Endotoxin, Azide and BSA Free [NBP3-09099]

Flow Cytometry: TWEAK R/TNFRSF12 Antibody (ITEM-4) - Low Endotoxin, Azide and BSA Free [NBP3-09099] - Separation of HUVEC cells stained using anti-human CD266 (ITEM-4) purified antibody (low endotoxin, concentration in sample 1 ug/ml, GAM APC, red-filled) from HUVEC cells unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).
Flow Cytometry: TWEAK R/TNFRSF12 Antibody (ITEM-4) - Low Endotoxin, Azide and BSA Free [NBP3-09099]

Flow Cytometry: TWEAK R/TNFRSF12 Antibody (ITEM-4) - Low Endotoxin, Azide and BSA Free [NBP3-09099]

Flow Cytometry: TWEAK R/TNFRSF12 Antibody (ITEM-4) - Low Endotoxin, Azide and BSA Free [NBP3-09099] - Surface staining pattern of HUVEC cells stained using anti-human CD266 (ITEM-4) purified antibody (low endotoxin, concentration in sample 1 ug/ml) GAM APC.

Applications for TWEAK R/TNFRSF12 Antibody (ITEM-4) - Low Endotoxin

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Phosphate buffered saline (PBS), pH 7.4

Format

Low Endotoxin

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TWEAK R/TNFRSF12

TWEAK (otherwise known as TNFRSF12A, Tumor necrosis factor receptor superfamily member 12A), is a member of the TNF family and was first described as a weak inducer of apoptosis in some cell types. It is thought to promote angiogenesis and the proliferation of endothelial cells as well as modulating cellular adhesion to matrix proteins. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library.

Long Name

TNF-like and Weak Inducer of Apoptosis Receptor

Alternate Names

CD266, Fn14, TNFRSF12, TNFRSF12A, TWEAKR

Gene Symbol

TNFRSF12A

Additional TWEAK R/TNFRSF12 Products

Product Documents for TWEAK R/TNFRSF12 Antibody (ITEM-4) - Low Endotoxin

Certificate of Analysis

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Product Specific Notices for TWEAK R/TNFRSF12 Antibody (ITEM-4) - Low Endotoxin

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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